Female Partner's Perception of Premature Ejaculation and Its Impact on Relationship Breakups, Relationship Quality, and Sexual Satisfaction

Premature ejaculation (PE) is a common sexual dysfunction affecting20% to 30% of men worldwide. Definitions of PE vary, but itis typically characterized by short intravaginal ejaculatory latencytime (IELT) with concomitant sexual dissatisfaction and distress.PE may be lifelong or acquired, but its etiology remains unclear.Treatment of PE typically involves pharmacotherapy, particularlywhen lifelong. Although there are numerous reports on the offlabeluse of selective serotonin reuptake inhibitors (SSRIs) andother compounds, only 2 treatments have been evaluated in randomizedcontrolled phase 3 clinical trials: PSD502 and dapoxetine(SSRI). Both significantly improved IELT and patient-reportedoutcome domains of ejaculatory control, sexual satisfaction, anddistress as measured by the index of premature ejaculation (IPE),compared with placebo. They constitute the focus of this review.Evidence demonstrated that PSD502, dapoxetine and other SSRIsall significantly improve the symptoms of PE. Systemic use of SSRIspresents risks associated with the known pharmacology of thisclass. PSD502 allows for topical on-demand treatment appliedapplied immediately before intercourse, and is not associated withsystemic adverse events.

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The comparison of on-demand caffeine consumption with squeezing technique on treating patients with premature ejaculation; a randomized clinical trial

10.53350/pjmhs211562005 ◽

2021 ◽

Vol 15 (6) ◽

pp. 2005-2010

Author(s):

Seyyed Hassan Saadat ◽

Khodabakhsh Ahmadi

Keyword(s):

Sexual Satisfaction ◽

Premature Ejaculation ◽

Post Treatment ◽

Common Disease ◽

Latency Time ◽

Caffeine Consumption ◽

On Demand ◽

Ejaculation Latency ◽

Significant Difference ◽

Pre Treatment

Background: The present study was aimed at evaluating the effect of on-demand caffeine consumption on treating patients with premature ejaculation (PE compared to squeezing technique. Methods: In this non-blind RCT, 42 otherwise healthy individuals with PE were divided into 2 groups of caffeine and squeezing technique group. The former received 100 mg of encapsulated caffeine for 3 weeks, 2 hours prior to each intercourse. Intra-vaginal ejaculation latency time and index of sexual satisfaction were calculated before and after treatment in both groups. Results: Mean age of the participants was 39.48±7.62 years. Despite the fact that there was no significant difference between pre-treatment and post-treatment values of both IELT and ISS between our 2 groups, significant difference was seen in both groups between pre-treatment and post-treatment values. Furthermore, no strong correlation was seen in pre-treatment IELT and ISS; however, statistically significant correlation was found in post-treatment values. Conclusion: Regarding the fact that caffeine is a well-known and widely-used drug in common disease, the use of this compound is highly unlikely to bear any stigma. Our study demonstrates that 100 mg of on-demand caffeine can equally increase both IELT and ISS significantly as squeezing technique. Further investigations are needed. Keywords: caffeine, premature ejaculation, squeezing technique, intra-vaginal ejaculation latency time, index of sexual satisfaction,

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Physical Activity and Sexual Health in Men

Спортске науке и здравље - АПЕИРОН ◽

10.7251/ssh1802117l ◽

2019 ◽

Vol 16 (2) ◽

Author(s):

Luka Leško ◽

Renata Barić ◽

Anamaria Ivanko

Keyword(s):

Physical Activity ◽

Sexual Health ◽

Sexual Satisfaction ◽

Sexual Desire ◽

Erectile Function ◽

Premature Ejaculation ◽

Age Groups ◽

Activity Level ◽

Male Students ◽

Physically Active

The primary aim of the study was to examine the correlation between the physical activity level and three factors of sexual health in men (sexual desire, sexual function and sexual satisfaction). The sample consisted of 509 male students aged 18 to 30 (M=19.70; SD=1.38). The results suggest a significantly better erectile function and sexual satisfaction in sufficiently physically active compared to insufficiently physically active men, while no significance was found in sexual desire and premature ejaculation. The findings indicate that the level of physical activity is positively related to sexual health factors, regardless of whether the dominant aerobic or anaerobic type of physical activity is practiced. Men with higher number of exercise hours on weekly basis have higher sexual desire and better erectile function. Men who are more satisfied with their own body image, have better erectile function. Although previous studies point to positive correlation between physical activity and sexual health in older age groups, this study points to better sexual health of physically active men already in the student age.

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Phosphodiesterase-5 Inhibitors for Premature Ejaculation: Systematic Review and Meta-Analysis of Placebo-Controlled Trials

American Journal of Men s Health ◽

10.1177/1557988320916406 ◽

2020 ◽

Vol 14 (3) ◽

pp. 155798832091640

Author(s):

Xuebao Zhang ◽

Nan Chi ◽

Miao Sun ◽

Zhengfei Shan ◽

Yulian Zhang ◽

...

Keyword(s):

Side Effects ◽

Sexual Satisfaction ◽

Premature Ejaculation ◽

Nasal Congestion ◽

Meta Analysis ◽

Efficacy And Safety ◽

Satisfaction Scale ◽

Phosphodiesterase 5 Inhibitors ◽

Comprehensive Search ◽

Phosphodiesterase 5

The purpose of this analysis is to assess the efficacy and safety of phosphodiesterase-5 inhibitors (PDE5Is) for the treatment of premature ejaculation (PE). A comprehensive search was performed to ascertain from trials about PDE5Is for the treatment of PE and compare the results, including intravaginal ejaculatory latency time (IVELT), score of sexual satisfaction scale, and side effects, between the group treated with PDE5Is and that treated with placebo. Seven studies involving a total of 471 patients were included in this meta-analysis. This analysis showed that patients who were treated with PDE5Is had significantly increased IVELT (mean difference [MD] 2.60; 95% CI [1.85, 3.36]; p < .00001) and score of sexual satisfaction scale (MD 2.04; 95% CI [0.78, 3.30]; p = .002) compared with the group on placebo. More patients had side effects while taking PDE5Is, such as headache, dizziness, flushing, and nasal congestion. PDE5Is were significantly more effective than placebo in the treatment of PE. Side effects were more common among patients who were treated with PDE5Is.

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