Aberrantly expressed recoverin is functionally associated with G-protein-coupled receptor kinases in cancer cell lines

2003 ◽  
Vol 300 (3) ◽  
pp. 669-673 ◽  
Author(s):  
Yasuhiro Miyagawa ◽  
Hiroshi Ohguro ◽  
Hiroki Odagiri ◽  
Ikuyo Maruyama ◽  
Tadao Maeda ◽  
...  
Keyword(s):  
G Protein ◽  
Cell Lines ◽  
Cancer Cell ◽  
Cancer Cell Lines ◽  
G Protein Coupled Receptor ◽  
Receptor Kinases ◽  
G Protein Coupled

The obestatin/G-protein coupled receptor 39 (GPR39) system in pancreatic cancer: proliferation studies in pancreatic cancer cell lines

Pancreatology ◽  
2019 ◽  
Vol 19 ◽  
pp. S162
Author(s):  
Lara Estevez-Perez ◽  
Saul Leal-Lopez ◽  
Vanesa Veloso-Noya ◽  
Begoña Otero-Alen ◽  
Carlos Seoane-Mosteiro ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
G Protein ◽  
Cell Lines ◽  
Cancer Cell ◽  
Pancreatic Cancer Cell ◽  
Cancer Cell Lines ◽  
G Protein Coupled Receptor ◽  
Cancer Proliferation ◽  
G Protein Coupled

scholarly journals The G Protein-Coupled Receptor Kinases (GRKs) in Chemokine Receptor-Mediated Immune Cell Migration: From Molecular Cues to Physiopathology

Cells ◽  
2021 ◽  
Vol 10 (1) ◽  
pp. 75
Author(s):  
Marta Laganà ◽  
Géraldine Schlecht-Louf ◽  
Françoise Bachelerie
Keyword(s):  
G Protein ◽  
Chemokine Receptor ◽  
Immune Cell ◽  
Neutrophil Migration ◽  
G Protein Coupled Receptor ◽  
Receptor Kinases ◽  
Immune Cell Migration ◽  
And Migration ◽  
G Protein Coupled ◽  
Gpcr Desensitization

Although G protein-coupled receptor kinases (GRKs) have long been known to regulate G protein-coupled receptor (GPCR) desensitization, their more recently characterized functions as scaffolds and signalling adapters underscore that this small family of proteins governs a larger array of physiological functions than originally suspected. This review explores how GRKs contribute to the complex signalling networks involved in the migration of immune cells along chemokine gradients sensed by cell surface GPCRs. We outline emerging evidence indicating that the coordinated docking of several GRKs on an active chemokine receptor determines a specific receptor phosphorylation barcode that will translate into distinct signalling and migration outcomes. The guidance cues for neutrophil migration are emphasized based on several alterations affecting GRKs or GPCRs reported to be involved in pathological conditions.

Correlation Between Beta-Adrenoceptors and G-Protein-Coupled Receptor Kinases in Pretransplantation Heart Failure

2008 ◽  
Vol 40 (9) ◽  
pp. 3014-3016 ◽  
Author(s):  
J. Agüero ◽  
L. Almenar ◽  
P. D'Ocon ◽  
E. Oliver ◽  
F. Montó ◽  
...  
Keyword(s):  
Heart Failure ◽  
G Protein ◽  
G Protein Coupled Receptor ◽  
Beta Adrenoceptors ◽  
Receptor Kinases ◽  
G Protein Coupled
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