Caffeine and sperm motility**Supported by World Health Organization grant M8-181-4-M191. This work was done at the University of California, Davis, School of Medicine, Davis, California.

1983 ◽  
Vol 39 (6) ◽  
pp. 845-848 ◽  
Author(s):  
Mohammed Mohsen Moussa
2021 ◽  
Vol 27 (2) ◽  
pp. 118-124
Author(s):  
Lilian J. Canamo ◽  
Jessica P. Bejar ◽  
Judy E. Davidson

University of California San Diego Health was set to launch its 13th annual Nursing and Inquiry Innovation Conference event in June 2020. However, the Coronavirus Disease 2019 (COVID-19) pandemic placed a barrier to large gatherings throughout the world. Because the World Health Organization designated 2020 as the Year of the Nurse and Midwife, the University committed to continuing the large-scale conference, converting to a virtual event. This article reviews the methodologies behind the delivery of the virtual event and implications for user engagement and learning on the blended electronic platform.


Author(s):  
Farwa Kazmi ◽  
Priyadarshini Ray ◽  
Muskaan Bhagchandani ◽  
Mohammed Khalil Mogharbel ◽  
Zubin Hassan Mubin ◽  
...  

Background: Researchers have become concerned with caffeine because of risks of addiction, as shown by latest studies. World Health Organization identify caffeine dependence as a clinical disorder. The objective of the study was to determine the prevalence of Caffeine Use Disorder among participants and identify determinants of Caffeine Use Disorder among participants.Methods: Questionnaires were distributed among university students who consumed caffeinated products and were older than 18 years of age. The research was carried out in 3 universities in Ajman, UAE. The data collected was analyzed using SPSS software.Results: It was found that the prevalence of Caffeine Use Disorder among caffeine consumers was 69%. The prevalence of Caffeine Use Disorder was significantly higher among students: who believed that their consumption had increased since joining the university (p<0.001) compared to other categories. The risk of Caffeine Use Disorder was higher among participants who consumed caffeine to: feel awake (OR=1.567, 95% CI:1.05-2.34), be more productive (OR=2.06, 95% CI:1.28-3.22), and because of peer pressure (OR=2.4, 95% CI:1.03-5.62) and who believed that their caffeine consumption had increased since joining the university (OR=3.68, 95%CI:2.49-5.44).Conclusion: The prevalence and risk of having Caffeine Use Disorder was high among university students, hence more research should be conducted and actions should be taken to reduce the prevalence of Caffeine Use Disorder.


Author(s):  
Prahlad Kadambi

Severe acute respiratory syndrome coronavirus 2 is currently spreading globally rapidly. The World Health Organization (WHO) named the virus as the 2019 novel corona virus (2019-nCoV) on January 7, 2020. On February 11th 2020, the illness associated was named as 2019 coronavirus disease (COVID-19). Subsequently, the WHO declared COVID-19 as a pandemic on 11 March 2020. The first case of COVID-19 was reported in India on 30 January 2020 in Thrissur, Kerala. This was the index case in India who tested positive after coming for a vacation. This individual was a student of the University of Wuhan. Subsequent cases were reported in Kerala. Subsequently, the number of cases in India increased to 519 as on 24th March 2020 with mortality in 7 patients as on 22nd March 2020 and 10 patients on 24th March 2020.


Biologics ◽  
2021 ◽  
Vol 1 (1) ◽  
pp. 2-40
Author(s):  
Iman Salahshoori ◽  
Noushin Mobaraki-Asl ◽  
Ahmad Seyfaee ◽  
Nasrin Mirzaei Nasirabad ◽  
Zahra Dehghan ◽  
...  

Coronaviruses belong to the “Coronaviridae family”, which causes various diseases, from the common cold to SARS and MERS. The coronavirus is naturally prevalent in mammals and birds. So far, six human-transmitted coronaviruses have been discovered. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was first reported in December 2019 in Wuhan, China. Common symptoms include fever, dry cough, and fatigue, but in acute cases, the disease can lead to severe shortness of breath, hypoxia, and death. According to the World Health Organization (WHO), the three main transmission routes, such as droplet and contact routes, airborne transmission and fecal and oral for COVID-19, have been identified. So far, no definitive curative treatment has been discovered for COVID-19, and the available treatments are only to reduce the complications of the disease. According to the World Health Organization, preventive measures at the public health level such as quarantine of the infected person, identification and monitoring of contacts, disinfection of the environment, and personal protective equipment can significantly prevent the outbreak COVID-19. Currently, based on the urgent needs of the community to control this pandemic, the BNT162b2 (Pfizer), mRNA-1273 (Moderna), CoronaVac (Sinovac), Sputnik V (Gamaleya Research Institute, Acellena Contract Drug Research, and Development), BBIBP-CorV (Sinofarm), and AZD1222 (The University of Oxford; AstraZeneca) vaccines have received emergency vaccination licenses from health organizations in vaccine-producing countries. Vasso Apostolopoulos, Majid Hassanzadeganroudsari


2021 ◽  
Vol 8 (Supplement_1) ◽  
pp. S460-S461
Author(s):  
Andrew Grose ◽  
Rima McLeod

Abstract Background Part of an essential “toolbox” to eliminate Toxoplasma gondii infection is prompt recognition of acute infection acquired during gestation, in order to initiate treatment for congenital toxoplasmosis (CT). From conception to one month post-partum, screening seronegative pregnant women monthly for antibody to the parasite enables treatment that prevents trans-placental transmission of newly acquired maternal Toxoplasma, or that attenuates signs and symptoms of CT. Tests that are highly sensitive and specific—and that meet the other World Health Organization ASSURED criteria for diagnostics—are very useful for this kind of screening. Herein, we evaluated the accuracy of a test that meets these criteria—the LDBIO Toxoplasma ICT IgG-IgM device (LDBIO)—and whether it eliminated difficulties of other tests with false positive IgM results. World Health Organization A.S.S.U.R.E.D. criteria These are criteria for ideal screening or diagnostic tests, as described in a September 2017 paper in the Bulletin of the World Health Organization. Our study focused mostly on sensitivity and specificity for the LDBIO immunochromatography test for IgG and IgM specific to Toxoplasma gondii. Methods Both parts of this study examined results generated by the LDBIO device—a point-of-care immunochromatography test for Toxoplasma IgG and IgM—using serum and whole blood samples. With whole blood, thirty microliters were collected using a glass micro hematocrit tube. With both sera and whole blood, samples were loaded into the well of the LDBIO device, which took 20 minutes to generate results. In the first part of this study, we summarized results from three published U.S. studies and added new data from an ongoing clinical trial at the University of Chicago Medical Center (UCMC). In the second part of this study, we compiled data on how the LDBIO device performed on a total of 69 samples from U.S. and French studies that had led to false positive results when tested with commercially available comparator tests. Four of these false positives came from the UCMC trial. UCMC Feasiblity Study Flowchart Flowchart for ongoing feasibility study on the LDBIO device at the University of Chicago Medical Center. Data from this study may inform whether the LDBIO test—which already has the CE Mark for use in Europe—will receive 510(k) approval from the Food and Drug Administration in the U.S. Steps for Using LDBIO Device (A,B) Clean fingertip; prick with lancet (if collecting whole blood only) (C,D) Collect 30 uL in capillary tube (WB only) (E,F) Apply serum or blood sample to well; add four drops buffer and wait about 20 minutes (G) How to interpret results: black line under “T” corresponds to IgG and/or IgM to T. gondii Results LDBIO had only one false negative for a total of 664 samples from three earlier U.S. studies and the UCMC feasibility study. Meanwhile, out of 69 total false positives from various non-reference laboratory comparator tests, such as the Bio-Rad Platelia and Siemens kits, the LDBIO generated zero false positives. LDBIO's Performance on U.S. Samples Since 2014 In all four U.S. studies (total 664 patients), the LDBIO device generated one false negative result and zero false positive results. LDBIO vs. Comparator Tests Since 2017 In these three clinical settings (69 total samples), LDBIO correctly avoided generating the same false positive that had been generated by a test already cleared for widespread use in the U.S. or France. Conclusion As LDBIO shows high sensitivity and specificity and can avoid confounding false positive results, this device merits consideration as a high-quality screening test that can assist public health efforts to improve CT care worldwide. Countries Working to Implement Regular Prenatal Screening for CT Prevention The countries in green represent countries currently working with the University of Chicago to implement regular prenatal screening programs for Toxoplasma gondii: U.S., Panama, Colombia, Brazil, Morocco, and France. Screening programs in all six countries rely on low-cost, highly-accurate screening technology that meets the WHO's ASSURED criteria. The LDBIO test -- which is already in use in France -- may become a usable resource in the other five countries if it gains FDA approval. Disclosures All Authors: No reported disclosures


2015 ◽  
Vol 25 (44) ◽  
pp. 165-175
Author(s):  
Jéssica Martielly Nunes Pereira ◽  
Fernando Verassani Laureano

O presente trabalho discute os resultados do monitoramento de ruído ambiental para os anos de 2010, 2011, 2012 e 2013 realizado pela PUC Minas em Betim no interior e no entorno do campus. O objetivo é testar a hipótese de que o ruído emitido no desempenho das atividades acadêmicas no interior do campus está em conformidade com a legislação e que, portanto, o cenário de poluição sonora do entorno não está diretamente associada às atividades da instituição. Das 244 aferições realizadas nos pontos externos 144 (59%) superaram os valores de referência. Dessas 21% apresentaram níveis sonoros superiores a 65 dB(A), ou seja, acima do limite recomendado pela Organização Mundial de Saúde (OMS) como limiar ao dano à saúde. Em contra partida, todas as 162 aferições realizadas nos pontos internos apresentaram valores abaixo do valor recomendado. Durante o período letivo a quantidade de medições em desconformidade apresentou um incremento em relação ao período de férias. Os dados também mostram que os níveis de ruído apresentaram maior amplitude durante o período letivo, aumentando assim a probabilidade de ocorrências de valores acima dos 65 dB(A). O incremento no quadro de poluição sonora no entorno da universidade está associado ao inerente aumento no fluxo de veículos e pessoas durante o período letivo.Palavra-chave: Monitoramento; Poluição sonora; Universidade; Betim.AbstractNoise monitoring had been performed inside and around PUC Minas Betim in order to test the hypothesys that surrounding noise pollution is not associated with academic activities. 144 (59%) of 244 external measurements exceeded legal benchmark values, in which 21% also exceeded World Health Organization 65 dB(A) threshold for health damage. On the other hand, 162 internal measurements showed results below the recommended limit. Although this pollution scenario is recurrent, the amount of non-conform measurements and noise amplitude rise during class times when compared to vacation periods. This rising is not however due the activities performed inside the campus but the associated increment on people and vehicles traffic around the university during class time.Keyword: Monitoring; Noise pollution; University; Betim.


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