Appropriateness of long-term proton pump inhibitor prescribing practices in a tertiary care teaching hospital

2000 ◽  
Vol 118 (4) ◽  
pp. A1237
Author(s):  
Roger L. Gebhard ◽  
Samuel B. Ho ◽  
John P. Toscano ◽  
Kathleen J. Ellingson ◽  
Cheryl Schultz ◽  
...  
Author(s):  
Abhishek Ghosh ◽  
Shankar Dey

Background: Proton pump inhibitors are one of the most commonly used drugs worldwide. Often they are used for inappropriate indications too, imposing economic burden to patients and governments. Many studies have showed equipotent efficacy of oral and intravenous proton pump inhibitor therapy. Despite that, most of the hospitalized patients receive intravenous proton pump inhibitor without appropriate indications. This study aimed to assess use of proton pump inhibitors in government hospital.Methods: It was an observational cross-sectional study done in the general medicine department of a tertiary care teaching hospital in Eastern India, including 800 noncritical patients. Objective was to assess the use of proton pump inhibitors (indications, route of administration, dosing frequency).Results: 100% patient received intravenous proton pump inhibitor irrespective of diagnosis. 80% of them received it twice daily and 18% received it once daily. Majority of the patients received intravenous proton pump inhibitor despite taking other drugs by oral route.Conclusions: Most of the PPI administration was done without appropriate indication. All patients received Intravenous proton pump inhibitors, which may impose economic burden on a government hospital. Majority of the patients received proton pump inhibitors twice daily. These approaches are not cost effective and need to be rectified.


2018 ◽  
Vol 147 ◽  
Author(s):  
Yi-Le Wu ◽  
Xi-Yao Yang ◽  
Meng-Shu Pan ◽  
Ruo-Jie Li ◽  
Xiao-Qian Hu ◽  
...  

AbstractHealthcare-associated infections (HAIs) are a major worldwide public-health problem, but less data are available on the long-term trends of HAIs and antimicrobial use in Eastern China. This study describes the prevalence and long-term trends of HAIs and antimicrobial use in a tertiary care teaching hospital in Hefei, Anhui, China from 2010 to 2017 based on annual point-prevalence surveys. A total of 12 505 inpatients were included; 600 HAIs were recorded in 533 patients, with an overall prevalence of 4.26% and a frequency of 4.80%. No evidence was found for an increasing or decreasing trend in prevalence of HAI over 8 years (trend χ2 = 2.15, P = 0.143). However, significant differences in prevalence of HAI were evident between the surveys (χ2 = 21.14, P < 0.001). The intensive care unit had the highest frequency of HAIs (24.36%) and respiratory tract infections accounted for 62.50% of all cases; Escherichia coli was the most common pathogen (16.67%). A 44.13% prevalence of antimicrobial use with a gradually decreasing trend over time was recorded. More attention should be paid to potential high-risk clinical departments and HAI types with further enhancement of rational antimicrobial use.


2013 ◽  
Vol 58 (5) ◽  
pp. 342 ◽  
Author(s):  
VinodS Deshmukh ◽  
ChetanrajG Bhamare ◽  
SuvarnaS Rathod ◽  
VijayM Motghare ◽  
RushikeshP Deshpande ◽  
...  

2013 ◽  
Vol 2013 ◽  
pp. 1-5 ◽  
Author(s):  
Pradeep R. Jadhav ◽  
Vijay V. Moghe ◽  
Yeshwant A. Deshmukh

In view of the advancement in drug development and availability of new ocular therapeutics in the discipline of ophthalmology, we attempted to study the drug utilization and describe the prescribing practices of ophthalmologists in a tertiary care teaching hospital. Method. A prospective, cross-sectional, observational study was conducted on patients attending Outpatient Department of Ophthalmology for curative complaints. Prescriptions of 600 patients treated were analyzed by the WHO prescribing indicators and additional indices. Results. Analysis showed that the average number of drugs per prescription was 1.49. Percentage of drugs prescribed by generic name was 2.35%. Percentage of encounters with antibiotics was 44.83%. Percentage of drugs prescribed from National Essential drug list (NEDL)/National Formulary of India (NFI) was 19.48%. Patient's knowledge of correct dosage was 93.83%. Antimicrobial agents were the most commonly prescribed drugs followed by antiallergy drugs and ocular lubricants. Fluoroquinolones accounted for 60% of the total antimicrobial drugs, of which gatifloxacin was the most frequently prescribed fluoroquinolone. Conclusion. The study indicated an awareness of polypharmacy, but showed ample scope for improvement in encouraging the ophthalmologists to prescribe by generic name and selection of essential drugs from NEDL/NFI.


2019 ◽  
Vol 10 (4) ◽  
pp. 55-60
Author(s):  
Saborni Dey ◽  
Vivek Sinha ◽  
Poonam Kachhawa

Background: The drug utilization research is a significant constituent of medical audit which helps in monitoring, evaluating and building required modifications in the prescribing practices to attain a rational and cost effective medical care. Aims and Objective: The objective of this study was to evaluate drug utilization design of Nonsteroidal anti-inflammatory drugs (NSAIDs) in a tertiary care teaching hospital, SIMS, Hapur. Material and Methods: This prospective, observational study was conducted in the outpatients of the Pain clinic during six months period to evaluate the prescribing pattern of analgesics in a tertiary care teaching hospital. After getting approval by Institutional Ethical committee, random prescriptions were collected from the OPD and scanned for the record purpose. The demographic data and the prescription were taken from 340 prescriptions. Data was analyzed as per WHO prescribing indicators. Results: A total 340 prescriptions were analyzed. The result revealed that NSAIDs as Diclofenac (75.21%) and Paracetamol (14.88%) were the most commonly prescribed analgesics. Average number of drugs in the present study was found to be 2.29. Percentage of drugs prescribed generic name was (21.02%). Percentage of encounters with an antibiotic was 12.95%, The use of injectable preparation was around 7.20%. Out of all the medicines, 85.90% were found written from Essential Drug List. Conclusion: The prescribing trend of NSAIDs indicate some deviation from the WHO recommendations. This touchstone data will be useful to plan more targeted research and to improve prescribing practices. These types of studies help to design policy for rational use of drugs and perioding training programs of physicians, establishing drug and therapeutic committee, drug information centres and regular educational interventions that can be beneficial for improving prescribing practice with rational drug usage.


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