43 Poor Sleep Quality Predicts Disease Relapse in Patients With Inflammatory Bowel Disease

2013 ◽  
Vol 144 (5) ◽  
pp. S-12 ◽  
Author(s):  
Tauseef Ali ◽  
Mohammad F. Madhoun ◽  
Amber Crosby ◽  
William C. Orr ◽  
David T. Rubin
Keyword(s):  
Inflammatory Bowel Disease ◽  
Sleep Quality ◽  
Bowel Disease ◽  
Poor Sleep ◽  
Disease Relapse ◽  
Poor Sleep Quality ◽  
Inflammatory Bowel

scholarly journals High C-Reactive Protein Is Associated with Poor Sleep Quality Independent of Nocturnal Symptoms in Patients with Inflammatory Bowel Disease

2015 ◽  
Vol 60 (7) ◽  
pp. 2136-2143 ◽  
Author(s):  
Robin G. Wilson ◽  
Betsy W. Stevens ◽  
Abra Y. Guo ◽  
Caitlin N. Russell ◽  
Anna Thornton ◽  
...  
Keyword(s):  
Inflammatory Bowel Disease ◽  
Sleep Quality ◽  
Bowel Disease ◽  
Poor Sleep ◽  
C Reactive Protein ◽  
Poor Sleep Quality ◽  
Reactive Protein ◽  
Inflammatory Bowel

scholarly journals P008 A systematic review and meta-analysis of inflammatory bowel disease activity and sleep quality

2021 ◽  
Vol 2 (Supplement_1) ◽  
pp. A24-A24
Author(s):  
A Barnes ◽  
P Spizzo ◽  
R Mountifield ◽  
P Bampton ◽  
J Andrews ◽  
...  
Keyword(s):  
Inflammatory Bowel Disease ◽  
Sleep Quality ◽  
Bowel Disease ◽  
Sleep Onset ◽  
Sleep Efficiency ◽  
Poor Sleep ◽  
Subjective Sleep Quality ◽  
Subjective Sleep ◽  
Inflammatory Bowel ◽  
Meta Analyses

Abstract Background Poor sleep quality has been associated with active inflammatory bowel disease (IBD) in several studies. This review examines sleep quality in people with active IBD and in those in remission, with meta-analyses performed, considering subjective and objective sleep quality and IBD activity. Methods Electronic databases were searched from inception to December 1st 2020. A random effects model was used with separate meta-analyses performed for objective and subjective sleep and IBD activity, considering sleep quality in active and inactive IBD. Results 19 studies were included in the qualitative review representing 4972 IBD patients. Subjective IBD activity (11 studies) was associated with subjective sleep quality with pooled odds ratio (OR) for subjective poor sleep in active IBD compared to remission of 3.04 (95% CI 2.41–3.83). Including only studies with objective sleep measures (5 studies), sleep efficiency was lower in those self-reporting active IBD and time awake post sleep onset was higher in those with active IBD. Objective IBD activity was associated with subjective poor sleep (4 studies), with pooled OR of 6.64 95% CI (3.02 – 14.59). Insufficient data was available to consider objective IBD activity and objective sleep quality. Conclusion IBD activity is associated with poor sleep using subjective and objective measures of sleep quality. This poor sleep manifests as decreased sleep efficiency and increased number of waking episodes post sleep onset. The relationship between objective IBD activity and sleep requires further investigation.

scholarly journals P061 Impact of Inflammatory Bowel Disease on sleep quality in a Mexican population attended in a referral center

2021 ◽  
Vol 116 (1) ◽  
pp. S16-S16
Author(s):  
Trujillo de la Fuente Korely ◽  
López Goméz Jesús ◽  
Cortes Espinosa Tomas ◽  
Perez-CabezadeVaca Rebeca ◽  
Paredes Amenabar Carlos ◽  
...  
Keyword(s):  
Inflammatory Bowel Disease ◽  
Sleep Quality ◽  
Bowel Disease ◽  
Mexican Population ◽  
Referral Center ◽  
Inflammatory Bowel

Inflammatory Bowel Disease Patients’ Willingness to Accept Medication Risk to Avoid Future Disease Relapse

2015 ◽  
Vol 110 (12) ◽  
pp. 1675-1681 ◽  
Author(s):  
Meenakshi Bewtra ◽  
Angelyn O Fairchild ◽  
Erin Gilroy ◽  
David A Leiman ◽  
Caroline Kerner ◽  
...  
Keyword(s):  
Inflammatory Bowel Disease ◽  
Bowel Disease ◽  
Willingness To Accept ◽  
Disease Relapse ◽  
Inflammatory Bowel ◽  
Medication Risk

Disparities in Objective Sleep Quality as Assessed Through Wrist Actigraphy in Minority Patients With Inflammatory Bowel Disease

2020 ◽  
Author(s):  
Taha Qazi ◽  
Alexander Smith ◽  
Megan Alexander ◽  
David Hammer ◽  
Ting Wu ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Inflammatory Bowel Disease ◽  
Sleep Quality ◽  
Odds Ratio ◽  
Poor Sleep ◽  
Psychosocial Issues ◽  
Wrist Actigraphy ◽  
Sleep Parameters ◽  
Inflammatory Bowel

Abstract Background Inflammatory bowel disease (IBD) is associated with a reduced quality of life. Minority patients with IBD specifically report more impairing symptoms compared with nonminority patients. Sleep quality, a key component of quality of life, is significantly compromised in minority patients compared with nonminority patients. Nevertheless, subjective and objective sleep assessments in minority patients with IBD have not explicitly been assessed. The purpose of this prospective cohort study is to assess and compare objective sleep parameters utilizing wrist actigraphy between minority and nonminority IBD patients. Methods In this institutional review board approved study, 74 patients with IBD were recruited and stratified into 2 cohorts by self-identification: white nonminority patients and minority patients. Patients in the minority cohort included black and Hispanic individuals (black and nonblack). Exclusion criteria included significant comorbidity, a history of an underlying sleep disorder, or patients who did not self-identify into categorized cohorts. Sleep was measured not only through wrist-based actigraphy but also with sleep surveys. Sleep parameters were compared between minority and nonminority cohorts. Regression analyses were performed to assess for factors independently associated with parameters of poor sleep quality. Results Sixty-four patients (86.4%) were included in the final analysis. Thirty-one individuals (48.4%) were categorized into the nonminority cohort, and 33 (51.6%) patients were in the minority cohort. A significantly higher number of minority patients had poorer sleep efficiency and fragmented sleep compared with nonminority patients (90.9% vs 67.7%; P = 0.03 and 87.8% vs 61.3%; P = 0.02). In the adjusted analysis, minority status was independently associated with poor sleep efficiency (odds ratio = 6.41; 95% confidence interval, 1.48-28.17; P = 0.0139) and fragmented sleep (odds ratio = 4.98; 95% confidence interval, 1.09-22.89; P = 0.0389). Conclusions Minority patients with IBD were shown to have poorer objective measures of sleep as assessed through wrist actigraphy compared to nonminority patients. Cultural competency in the care of minority patients with IBD, specifically focusing on the management of psychosocial issues, is needed to address these disparities in sleep. The inclusion of minority patients with IBD in studies investigating sleep and other psychosocial issues are warranted not only to assess potential disparities in disease course but also to determine the etiologies of poor sleep in minority patients with IBD.

scholarly journals Integrating omics for a better understanding of Inflammatory Bowel Disease: a step towards personalized medicine

2019 ◽  
Vol 17 (1) ◽  
Author(s):  
Manoj Kumar ◽  
Mathieu Garand ◽  
Souhaila Al Khodor
Keyword(s):  
Inflammatory Bowel Disease ◽  
Bowel Disease ◽  
Current Knowledge ◽  
Clinical Decision ◽  
Complex Nature ◽  
Knowledge Gap ◽  
Disease Relapse ◽  
Microbial Dysbiosis ◽  
Metabolic Dysregulation ◽  
Inflammatory Bowel

Abstract Background Inflammatory Bowel Disease (IBD) is a multifactorial chronic disease. Understanding only one aspect of IBD pathogenesis does not reflect the complex nature of IBD nor will it improve its clinical management. Therefore, it is vital to dissect the interactions between the different players in IBD pathogenesis in order to understand the biology of the disease and enhance its clinical outcomes. Aims To provide an overview of the available omics data used to assess the potential mechanisms through which various players are contributing to IBD pathogenesis and propose a precision medicine model to fill the current knowledge gap in IBD. Results Several studies have reported microbial dysbiosis, immune and metabolic dysregulation in IBD patients, however, this data is not sufficient to create signatures that can differentiate between the disease subtypes or between disease relapse and remission. Conclusions We summarized the current knowledge in the application of omics in IBD patients, and we showed that the current knowledge gap in IBD hinders the improvements of clinical decision for treatment as well as the prediction of disease relapse. We propose one way to fill this gap by implementing integrative analysis of various omics datasets generated from one patient at a single time point.

Adherence in inflammatory bowel disease (IBD): a clinical review

2019 ◽  
Vol 17 (6) ◽  
pp. 24-27
Author(s):  
Palle Bager ◽  
Susanna Jäghult
Keyword(s):  
Inflammatory Bowel Disease ◽  
Maintenance Therapy ◽  
Clinical Review ◽  
Bowel Disease ◽  
Topical Treatment ◽  
Disease Relapse ◽  
Adherence To Treatment ◽  
Different Types ◽  
Inflammatory Bowel ◽  
Stool Samples

Adherence to treatment can be challenging, especially in chronic diseases. In inflammatory bowel disease (IBD), maintenance therapy is common to prevent a disease relapse, and adherence becomes even more of a challenge during remission. Furthermore, practical problems with taking topical treatment can increase the likelihood of non-adherence. In IBD, the definition adherence can be expanded beyond taking medication to factors like leaving blood or stool samples, keeping appointments or adjusting behaviour regarding smoking or diet. This review provides a taxonomy of different types of non-adherence and indicates how these types call for different interventions. Furthermore, the article describes how IBD nurses can open up conversations with patients that will hopefully lead to improvements in their adherence.

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