Sa1684 Common Food Additive Carrageenan Stimulates Wnt/β-Catenin Signaling Pathway in Colonic Epithelium by Inhibition of Nucleoredoxin Reduction

2013 ◽  
Vol 144 (5) ◽  
pp. S-282
Author(s):  
Joanne K. Tobacman ◽  
Sumit Bhattacharyya
2013 ◽  
Vol 66 (1) ◽  
pp. 117-127 ◽  
Author(s):  
Sumit Bhattacharyya ◽  
Leonid Feferman ◽  
Sujata Borthakur ◽  
Joanne K. Tobacman

2019 ◽  
Vol 12 (11) ◽  
pp. 5433
Author(s):  
K. Mythili ◽  
C. Vichitra ◽  
S. Gayatri ◽  
K. Chitra
Keyword(s):  

2015 ◽  
Vol 7 (3) ◽  
pp. 234-242 ◽  
Author(s):  
Awad Abdel Twab Mahmoud ◽  
Gamal Mohamedin Hassan ◽  
Abdel Moneim Sadek Hassan ◽  
Abdel Krem Mohammed Abdel Latif ◽  
Mohamed Fawzy Ramadan

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Anton Tkachenko ◽  
Anatolii Onishchenko ◽  
Yevgen Posokhov ◽  
Alexander Roshal ◽  
Valeriy Myasoedov ◽  
...  

Abstract Objectives To estimate the state of phospholipid bilayer of rats WBCs exposed to a common food additive E407a, which is used as a thickener and emulsifier, during 4 h using a fluorescent probe − ortho-hydroxy derivative of 2,5-diaryl-1,3-oxazole. Materials and methods Steady-state fluorescence spectroscopy: a study by the environment-sensitive fluores-cent probe − 2-(2′-hydroxy-phenyl)-5-phenyl-1,3-oxazole (probe O1O). Results Changes are detected in the spectra of the fluorescent probe bound to rat WBCs treated with the solutions of E407a of various concentrations in comparison with the corresponding spectra of the probe incubated with the untreated leukocytes. The decrease in polarity and proton-donor ability is observed in the lipid membranes of leukocytes in the region, where the probe locates. Conclusions Our findings suggest a higher dehydration of leukocyte membranes of rats treated with a common food additive E407a at high concentrations and, thus, indicate that exposure to high doses of E407a leads to the increase in the lipid order (i.e. to decrease in fluidity) of the membranes of rat WBCs.


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