Racial/Ethnic Disparities in Early-Stage Hepatocellular Carcinoma Curative Treatment Rates Within Asian and Hispanics in Los Angeles

2017 ◽  
Vol 152 (5) ◽  
pp. S1197
Author(s):  
Chiranjeevi Gadiparthi ◽  
Rosann Cholankeril ◽  
Eddie L. Copelin ◽  
Mairin Joseph-Talreja ◽  
Muhammad Ali Khan ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Los Angeles ◽  
Early Stage ◽  
Ethnic Disparities ◽  
Curative Treatment ◽  
Racial Ethnic

scholarly journals HEADS-UP: Understanding and Problem-Solving

Stroke ◽  
2020 ◽  
Vol 51 (11) ◽  
pp. 3375-3381
Author(s):  
Bruce Ovbiagele
Keyword(s):  
Problem Solving ◽  
Health Equity ◽  
Neurological Disorders ◽  
Underserved Populations ◽  
Early Stage ◽  
Ethnic Disparities ◽  
Grant Writing ◽  
Scientific Content ◽  
Stroke Incidence ◽  
Racial Ethnic

There are substantial and longstanding inequities in stroke incidence, prevalence, care, and outcomes. The Health Equity and Actionable Disparities in Stroke: Understanding and Problem-Solving (HEADS-UP) symposium is an annual multidisciplinary scientific and educational forum targeting major inequities in cerebrovascular disease, with the ultimate objective of helping to bridge major inequities in stroke, and promptly translating scientific results into routine clinical practice, for the benefit of vulnerable and underserved populations. HEADS-UP is a collaborative undertaking by the National Institute of Neurological Disorders and Stroke and the American Stroke Association and is held the day before the annual International Stroke Conference. In 2020, the HEADS-UP focused on the topic of racial/ethnic disparities in stroke and comprised invited lectures on determinants of racial/ethnic inequities in stroke as well as emerging interventions or promising strategies designed to overcome these inequities. Competitively selected travel award scholarships were given to 19 early stage investigators who presented posters at professor moderated sessions; engaged in several career development activities aimed imparting grant writing skills, knowledge about climbing the academic ladder, and striving for work-life balance; and participated in networking events. This Health Equity edition of Focused Updates will feature an overview of the HEADS-UP 2020 symposium proceedings and articles covering the key scientific content of the major lectures delivered during the symposium including the presentation by the award-winning plenary speaker. Starting in 2021, HEADS-UP will expand to include 5 major inequities in stroke (racial/ethnic, sex, geographic, socioeconomic, and global) and seeks to be a viable avenue to meet the health equity goals of the American Heart Association/American Stroke Association, National Institutes of Neurological Disorders and Stroke, and World Stroke Organization.

40 Racial/Ethnic Disparities in Hepatocellular Carcinoma Care Delivery

2016 ◽  
Vol 150 (4) ◽  
pp. S14 ◽  
Author(s):  
Olutola A. Yerokun ◽  
Adam Yopp ◽  
Neehar D. Parikh ◽  
Sahil Mittal ◽  
Steven J. Scaglione ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Care Delivery ◽  
Ethnic Disparities ◽  
Racial Ethnic

scholarly journals Investigating Racial/Ethnic Disparities in the Association Between AHEI-2010 and Change in Cystatin C in a Representative Sample of Older Americans

2021 ◽  
Vol 5 (Supplement_2) ◽  
pp. 1015-1015
Author(s):  
Nicholas Bishop ◽  
Jie Zhu
Keyword(s):  
Older Adults ◽  
Dietary Intake ◽  
Kidney Function ◽  
Cystatin C ◽  
Early Stage ◽  
Ethnic Disparities ◽  
Healthy Eating Index ◽  
Dietary Quality ◽  
Linear Modeling ◽  
Racial Ethnic

Abstract Objectives Cystatin C (Cys C) is a promising biomarker for early-stage chronic kidney disease. Dietary intake plays an essential role in the prevention of kidney function decline, which has yet to be examined in relation to changes in Cys C among older adults. Our objective was to test whether scores on the Alternative Healthy Eating Index-2010 (AHEI-2010) were associated with change in Cys C from 2012–2016 and if this varied by race/ethnicity. Methods Observations were drawn from the Health and Retirement Study. Blood spot collection and examination occurred in 2012 and 2016, participant attributes were measured in 2012, and dietary assessment was conducted by a validated dietary frequency questionnaire in 2013. The sample was restricted to respondents aged ≥65 years who were White (n = 789), Black (n = 108), or Hispanic (n = 61) and had biomarkers measured in 2012 and 2016 (n = 958). Serum Cys C (mg/L) was constructed to be equivalent to the 1999–2002 NHANES scale. Dietary quality was measured using AHEI-2010. Autoregressive linear modeling adjusting for covariates and sampling design was used to examine the associations of interest. Results Mean serum Cys C was 1.20 ± 0.44 mg/L (SD) in 2012 and 1.25 ± 0.45 mg/L in 2016, and mean AHEI-2010 score was 58.11 ± 11.0. Greater AHEI-2010 was associated with lower serum Cys C level at baseline (b = −.004, SE = .013, P = .002) and less rapid increase in the Cys C level from 2012–2016 (b = −.003, SE = .012, P = .024). The association between AHEI-2010 and change in serum Cys C was significantly different for Whites and Hispanics (b = .128, SE = .031, P < .001), but null when comparing Whites and Blacks. AHEI-2010 was negatively associated with change in Cys C for Whites, and positively associated with change in Cys C among Hispanics. Stratified analyses suggested that AHEI-2010 was not significantly different for Whites and Hispanics. Hispanics had significantly lower household income, assets, and educational attainment than Whites, and greater levels of food insecurity. Conclusions Our results indicate that dietary quality has a divergent association with change in serum Cys C for White and Hispanic older adults. These results suggest the need for examination of how disparities in socioeconomic status may influence the effect of dietary intake on kidney function for older adults from different racial/ethnic backgrounds. Funding Sources No funding.

Racial/ethnic disparities in lung cancer stage of diagnosis and survival

2009 ◽  
Vol 27 (15_suppl) ◽  
pp. 8080-8080
Author(s):  
L. E. Raez ◽  
T. Koru-Sengul ◽  
G. Allen ◽  
J. Clarke ◽  
E. S. Santos ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Regression Model ◽  
Median Survival ◽  
Cox Regression ◽  
Early Stage ◽  
Ethnic Disparities ◽  
Female Gender ◽  
Cox Regression Model ◽  
Referent Group ◽  
Racial Ethnic

8080 Background: There are differences in the treatment outcome of non-small cell lung cancer (NSCLC) patients (pts) between non-Hispanic whites (NHW) and African Americans (AA). Little is known regarding the outcomes of Hispanics (H). Methods: Registry data on 2,696 pts with NSCLC treated during 1999–2006 was obtained. The objective of the study was to evaluate differences in NSCLC survival according to different ethnicities. Chi-square was used to compare distribution of tumor stage. Survival curves were compared using log-rank test for each of the tumor stages. Adjusted hazard ratios (AHR) and 95% confidence intervals (95% CI) were reported based on the results of a multivariate Cox regression model for overall survival (OS) with adjustment for gender, age at diagnosis, and race. Results: Most pts had stage III/IV at diagnosis; majority of the AA or HW presented in advanced stage compared with NHW. Significantly higher proportions of AA and H were diagnosed with stage IV compared to NHW ( Table ). Mean age at diagnosis was 62 yrs (AA 58, H 60, and NHW 66yrs) and it was significantly different among the 3 groups (one-way ANOVA, p<0.0001). AA and H have significantly shorter stage-specific median survival for early stage compared to that in NHW ( Table ). In pts with advanced stages the pattern was similar: AA and H have a significantly shorter median survival than that in NHW. In early-stage pts, significant predictors for OS from multivariate Cox regression model were female gender (AHR=0.65; p<0.001), AA (NHW as the referent group; AHR=2.67; p<0.0001), and H (NHW as the referent group; AHR=2.01; p<0.0001). In late-stage pts, significant predictors for OS were female gender (AHR=0.79; p=0.0002), AA (NHW as the referent group; AHR=1.53; p<0.0001, and H (NHW as the referent group; AHR=1.28; p=0.0006). Conclusions: NHW pts had better OS than H and AA; we will evaluate whether gene expression profiles or presence of EGFR overexpression have an impact on racial/ethnic disparities in the outcome of NSCLC. [Table: see text] No significant financial relationships to disclose.

Racial/ethnic disparities in hepatocellular carcinoma treatment and survival: Are we making progress?

2015 ◽  
Vol 33 (15_suppl) ◽  
pp. e17591-e17591
Author(s):  
Oxana V. Makarova-Rusher ◽  
Katerina A. Erokhina ◽  
Austin G. Duffy ◽  
Susanna Varkey Ulahannan ◽  
Tim F. Greten
Keyword(s):  
Hepatocellular Carcinoma ◽  
Ethnic Disparities ◽  
Racial Ethnic

Racial Disparities in Use of Chiropractic Services by Medicare Beneficiaries Aged 65 to 99 in Los Angeles County, California

2015 ◽  
Vol 21 (2) ◽  
pp. 131-137 ◽  
Author(s):  
James M. Whedon ◽  
Melissa N. Kimura ◽  
Reed B. Phillips
Keyword(s):  
Los Angeles ◽  
Racial Disparities ◽  
Los Angeles County ◽  
Local Level ◽  
Ethnic Disparities ◽  
State Level ◽  
Chiropractic Care ◽  
Geographic Variations ◽  
Racial Ethnic ◽  
Zip Code

Racial and ethnic disparities in utilization of chiropractic services have been described at the state level, but little is known about such local disparities. We analyzed Medicare data for the year 2008 to evaluate by ZIP code for utilization of chiropractic services among older adults in Los Angeles County, California. We evaluated for availability and use of chiropractic services by racial/ethnic category, quantified geographic variations by coefficient of variation, and mapped utilization by selected racial/ethnic categories. Among 7502 beneficiaries who used chiropractic services, 72% were white, 12% Asian, 1% black, 1% Hispanic, and 14% other/unknown. Variation in the number of beneficiaries per ZIP code who used chiropractic services was highest among Hispanics, blacks, and Asians. We found evidence of racial disparities in use of chiropractic services at the local level in Los Angeles County. Older blacks and Hispanics in Los Angeles County may be underserved with regard to chiropractic care.

Tu1491 - Early Tumor Detection and Curative Treatment Receipt Mediate Racial and Ethnic Disparities in Hepatocellular Carcinoma Prognosis

2018 ◽  
Vol 154 (6) ◽  
pp. S-1237
Author(s):  
Nicole E. Rich ◽  
Caitlin Hester ◽  
Mobolaji Odewole ◽  
Caitlin C. Murphy ◽  
Neehar D. Parikh ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Ethnic Disparities ◽  
Tumor Detection ◽  
Curative Treatment ◽  
Racial And Ethnic Disparities ◽  
Early Tumor
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