Mo1547 – Impact of Transanal Irrigation (TAI) Device (Peristeen®, Coloplast) in Management of Pediatric Patients with Chronic Fecal Incontinence and Constipation

2019 ◽  
Vol 156 (6) ◽  
pp. S-776
Author(s):  
Puanani Hopson ◽  
Samit Patel ◽  
Jeffrey A. Bornstein ◽  
Shaista Safder
Keyword(s):  
Fecal Incontinence ◽  
Pediatric Patients ◽  
Transanal Irrigation

scholarly journals Effects of Transanal Irrigation on Gut Microbiota in Pediatric Patients with Spina Bifida

2021 ◽  
Vol 10 (2) ◽  
pp. 224
Author(s):  
Akira Furuta ◽  
Yasuyuki Suzuki ◽  
Ryosuke Takahashi ◽  
Birte Petersen Jakobsen ◽  
Takahiro Kimura ◽  
...  
Keyword(s):  
Spina Bifida ◽  
16S Rrna ◽  
Gut Microbiota ◽  
Pediatric Patients ◽  
Host Immune System ◽  
Healthy Controls ◽  
Transanal Irrigation ◽  
Rrna Sequencing ◽  
Before And After ◽  
Neurogenic Bowel

Recent studies using 16S rRNA-based microbiota profiling have demonstrated dysbiosis of gut microbiota in constipated patients. The aim of this study was to investigate the changes in gut microbiota after transanal irrigation (TAI) in patients with spina bifida (SB). A questionnaire on neurogenic bowel disfunction (NBD), Bristol scale, and gut microbiota using 16S rRNA sequencing were completed in 16 SB patients and 10 healthy controls aged 6–17 years. Then, 11 of 16 SB patients with moderate to severe NBD scores received TAI for 3 months. Changes in urine cultures were also examined before and after the TAI treatments. In addition, correlation of gut microbiota and Bristol scale was analyzed. Significantly decreased abundance in Faecalibacterium, Blautia and Roseburia, and significantly increased abundance in Bacteroides and Roseburia were observed in the SB patients compared with controls and after TAI, respectively. The abundance of Roseburia was significantly correlated positively with Bristol scale. Urinary tract infection tended to decrease from 82% to 55% after TAI (p = 0.082) despite persistent fecal incontinence. Butyrate-producing bacteria such as Roseburia play a regulatory role in the intestinal motility and host immune system, suggesting the effects of TAI on gut microbiota.

Transanal irrigation is effective in functional fecal incontinence

2017 ◽  
Vol 176 (6) ◽  
pp. 731-736 ◽  
Author(s):  
Cecilie Siggaard Jørgensen ◽  
Konstantinos Kamperis ◽  
Line Modin ◽  
Charlotte Siggaard Rittig ◽  
Søren Rittig
Keyword(s):  
Fecal Incontinence ◽  
Transanal Irrigation

Long-Term Outcome and Safety of Transanal Irrigation for Constipation and Fecal Incontinence

2009 ◽  
Vol 52 (2) ◽  
pp. 286-292 ◽  
Author(s):  
Peter Christensen ◽  
Klaus Krogh ◽  
Steen Buntzen ◽  
Fariborz Payandeh ◽  
Søren Laurberg
Keyword(s):  
Fecal Incontinence ◽  
Term Outcome ◽  
Long Term Outcome ◽  
Transanal Irrigation

Percutaneous Cecostomy for Management of Fecal Incontinence in Pediatric Patients

2007 ◽  
Vol 18 (8) ◽  
pp. 982-985 ◽  
Author(s):  
Sergio Sierre ◽  
Jose Lipsich ◽  
Horacio Questa ◽  
Marcela Bailez ◽  
Julieta Solana
Keyword(s):  
Fecal Incontinence ◽  
Pediatric Patients

scholarly journals Advanced Management Protocol of Transanal Irrigation in Order to Improve the Outcome of Pediatric Patients with Fecal Incontinence

Children ◽  
2021 ◽  
Vol 8 (12) ◽  
pp. 1174
Author(s):  
Anna Maria Caruso ◽  
Mario Pietro Marcello Milazzo ◽  
Denisia Bommarito ◽  
Vincenza Girgenti ◽  
Glenda Amato ◽  
...  
Keyword(s):  
Fecal Incontinence ◽  
Neurological Impairment ◽  
Transanal Irrigation ◽  
Rectal Ultrasound ◽  
Best Response ◽  
Management Protocol ◽  
Pre Treatment ◽  
Work Up ◽  
Functional Incontinence ◽  
Fecal Score

Background: Transanal irrigation (TAI) is employed for children with fecal incontinence, but it can present several problems which require a study of their outcomes among different pathologies and without a tailored work up. The aim of our study was to evaluate the effectiveness of an advanced protocol in order to tailor TAI, prevent complications, and evaluate outcomes. Methods: We included 70 patients (14 anorectal malformation, 12 Hirschsprung’s disease, 24 neurological impairment, 20 functional incontinence) submitted to a comprehensive protocol with Peristeen®: fecal score, volumetric enema, rectal ultrasound, anorectal 3D manometry, and diary for testing and parameter adjustment. Results: Among the patients, 62.9% needed adaptations to the parameters, mainly volume of irrigated water and number of puffs of balloon. These adaptations were positively correlated with pre-treatment manometric and enema data. In each group, the improvement of score was statistically significant in all cases (p 0.000); the main factor influencing the efficacy was the rate of sphincter anomalies. The ARM group had slower improvement than other groups, whereas functional patients had the best response. Conclusions: Our results showed that TAI should not be standardized for all patients, because each one has different peculiarities; evaluation of patients before TAI with rectal ultrasound, enema, and manometry allowed us to tailor the treatment, highlighting different outcomes among various pathologies, thus improving the efficacy

scholarly journals Impact of Transanal Irrigation Device in Management of Children with Fecal Incontinence and Constipation

2020 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Samit Patel ◽  
Puanani Hopson ◽  
Jeffrey Bornstein ◽  
Shaista Safder
Keyword(s):  
Fecal Incontinence ◽  
Transanal Irrigation

Infections related to intrathecal baclofen therapy in children and adults: frequency and risk factors

2009 ◽  
Vol 4 (5) ◽  
pp. 487-493 ◽  
Author(s):  
Anne-Berit Fjelstad ◽  
Jorunn Hommelstad ◽  
Angelika Sorteberg
Keyword(s):  
Risk Factors ◽  
Fecal Incontinence ◽  
Causative Agent ◽  
Surgical Procedure ◽  
Pediatric Patients ◽  
Intrathecal Baclofen ◽  
Catheter Insertion ◽  
Peg Tube ◽  
Screening Trial ◽  
Pump Implantation

Object The purpose of this study was to determine the frequency of infection and to identify risk factors for infection in connection with the implantation of an intrathecal baclofen (ITB) pump. Methods This retrospective study included all pediatric and adult patients who received ITB at Rikshospitalet during the years 1999–2005. A database was created that included the following variables: patient age, sex, weight, diagnosis, surgical procedure performed, presence of a percutaneous endoscopic gastrostomy (PEG) tube, urinary as well as fecal incontinence, anesthetist's classification of patient status (American Society of Anesthesiologists grade), timing of antibiotics administration, surgeon, assisting nurse, and surgical procedure time. Moreover, the mode of intrathecal screening trial (transcutaneous vs subcutaneous catheter insertion) and any complications were registered. The authors differentiated between deep and superficial infection, and they registered the causative agent. Results A total of 163 patients received ITB; of these, 91 were pediatric patients (median age 10 years), and 72 were adults (median age 44 years). A total of 408 surgical procedures were performed. No infections occurred in direct relation to the screening trials. When a pump was implanted subsequent to a screening trial with transcutaneous catheter insertion, the rate of infection was 9% in the pediatric patients. The corresponding infection rate for pumps implanted after a screening trial with a subcutaneous distal catheter (Albright method) was 12%. This difference was not significant. There was a significantly higher incidence of deep infections following pump implantation in the pediatric group (p = 0.028) than in the adult group. The presence of a PEG tube increased the incidence of infection (p = 0.008) and may be one of the main reasons for a higher frequency of infections in children. When the patient suffered urinary and/or fecal incontinence, there was a higher chance of infection (p = 0.021). The surgical time was significantly longer in the pediatric group than in adults; however, the length of the surgical procedure had no impact on the occurrence of infection. The most common causative agent was Staphylococcus aureus; this microbe was responsible for 69% of deep infections. Also, 69% of deep infections occurred within 1 month after surgery. Conclusions The rate of infection is significantly higher in children undergoing ITB pump implantation than it is in adults. Screening trials applying the Albright method fail to reduce the frequency of infection subsequent to pump implantation. The presence of a PEG tube has the greatest significance as a predictor of infection.

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