Sa574 RISK FACTORS FOR DISORDERED EATING AMONG PATIENTS WITH INFLAMMATORY BOWEL DISEASES

2021 ◽  
Vol 160 (6) ◽  
pp. S-557-S-558
Author(s):  
Gianna Stoleru ◽  
Andrew R. Leopold ◽  
Amanda Auerbach ◽  
Shelley Nehman ◽  
Uni Wong
Keyword(s):  
Risk Factors ◽  
Disordered Eating ◽  
Inflammatory Bowel Diseases ◽  
Bowel Diseases ◽  
Inflammatory Bowel

scholarly journals 1119 Genetic Risk Factors for Serious Infections in Inflammatory Bowel Diseases

2016 ◽  
Vol 150 (4) ◽  
pp. S224-S225
Author(s):  
Saranya Sasidharan ◽  
Vijay Yajnik ◽  
Hamed Khalili ◽  
John Garber ◽  
Comas Giallourakis ◽  
...  
Keyword(s):  
Risk Factors ◽  
Inflammatory Bowel Diseases ◽  
Genetic Risk ◽  
Genetic Risk Factors ◽  
Serious Infections ◽  
Bowel Diseases ◽  
Inflammatory Bowel

scholarly journals Articular manifestations in patients with inflammatory bowel disease treated with vedolizumab

Rheumatology ◽  
2020 ◽  
Vol 59 (11) ◽  
pp. 3275-3283 ◽  
Author(s):  
Anastasia Dupré ◽  
Michael Collins ◽  
Gaétane Nocturne ◽  
Franck Carbonnel ◽  
Xavier Mariette ◽  
...  
Keyword(s):  
Risk Factors ◽  
Ulcerative Colitis ◽  
Inflammatory Bowel Disease ◽  
Inflammatory Bowel Diseases ◽  
Bowel Disease ◽  
Bowel Diseases ◽  
History Of ◽  
Musculoskeletal Manifestations ◽  
Inflammatory Bowel

Abstract Objective Vedolizumab (VDZ) has been incriminated in the occurrence of articular manifestations in patients with inflammatory bowel diseases (IBDs). The aim of this study was to describe musculoskeletal manifestations occurring in IBD patients treated by VDZ and to identify risk factors. Methods In this retrospective monocentric study, we included all consecutive patients treated by VDZ for IBD in our hospital. Incident musculoskeletal manifestations occurring during VDZ treatment were analysed and characteristics of patients with and without articular inflammatory manifestations were compared. Results Between 2013 and 2017, 112 patients were treated with VDZ for IBD: ulcerative colitis (n = 59), Crohn’s disease (n = 49) and undetermined colitis (n = 4). Four patients (3.6%) had a history of SpA, whereas 13 (11.6%) had a history of peripheral arthralgia. Some 102 (91.1%) patients had previously received anti-TNF. After a mean (S.d.) follow-up of 11.4 (8.6) months, 32 (28.6%) patients presented 35 musculoskeletal manifestations, of which 18 were mechanical and 17 inflammatory. Among the latter, 11 had axial or peripheral SpA, 5 had early reversible arthralgia and 1 had chondrocalcinosis (n = 1). Among the 11 SpA patients, only 3 (2.6%) had inactive IBD and may be considered as paradoxical SpA. The only factor associated with occurrence of inflammatory manifestations was history of inflammatory articular manifestation [7/16 (43.8%) vs 10/80 (12.5%), P = 0.007]. Conclusion Musculoskeletal manifestations occurred in almost 30% of IBD patients treated with VDZ, but only half of them were inflammatory. Since most of the patients previously received anti-TNF, occurrence of inflammatory articular manifestations might rather be linked to anti-TNF discontinuation than to VDZ itself.

scholarly journals Environment and the Inflammatory Bowel Diseases

2013 ◽  
Vol 27 (3) ◽  
pp. e18-e24 ◽  
Author(s):  
Alexandra Frolkis ◽  
Levinus A Dieleman ◽  
Herman W Barkema ◽  
Remo Panaccione ◽  
Subrata Ghosh ◽  
...  
Keyword(s):  
Risk Factors ◽  
Environmental Factors ◽  
Environmental Risk ◽  
Inflammatory Bowel Diseases ◽  
Current Knowledge ◽  
Environmental Risk Factors ◽  
Past Century ◽  
Commensal Flora ◽  
Bowel Diseases ◽  
Inflammatory Bowel

Inflammatory bowel diseases (IBD), which consists of Crohn disease and ulcerative colitis, are chronic inflammatory conditions of the gas-trointestinal tract. In genetically susceptible individuals, the interaction between environmental factors and normal intestinal commensal flora is believed to lead to an inappropriate immune response that results in chronic inflammation. The incidence of IBD have increased in the past century in developed and developing countries. The purpose of the present review is to summarize the current knowledge of the association between environmental risk factors and IBD. A number of environmental risk factors were investigated including smoking, hygiene, microorganisms, oral contraceptives, antibiotics, diet, breast-feeding, geographical factors, pollution and stress. Inconsistent findings among the studies highlight the complex pathogenesis of IBD. Additional studies are necessary to identify and elucidate the role of environmental factors in IBD etiology.

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