scholarly journals THE EFFECT OF ORANGE JUICE ON THE CALCIUM, PHOSPHORUS, MAGNESIUM, AND NITROGEN RETENTION AND URINARY ORGANIC ACIDS OF GROWING CHILDREN

1925 ◽  
Vol 66 (2) ◽  
pp. 829-845
Author(s):  
Margaret S. Chaney ◽  
Katharine Blunt
Keyword(s):  
Organic Acids ◽  
Orange Juice ◽  
Nitrogen Retention ◽  
Urinary Organic Acids ◽  
Calcium Phosphorus

scholarly journals GC-MS profiling of urinary organic acids evaluated as a quantitative method

1996 ◽  
Vol 42 (10) ◽  
pp. 1609-1615 ◽  
Author(s):  
P Duez ◽  
A Kumps ◽  
Y Mardens
Keyword(s):  
Organic Acids ◽  
Classical Method ◽  
Internal Standard ◽  
Selected Ion Monitoring ◽  
Practical Procedure ◽  
Urinary Organic Acids ◽  
Relative Standard ◽  
Analytical Response ◽  
Quantitative Results ◽  
Curvilinear Relationships

Abstract We assessed the quantitative performances of a classical method for profiling urinary organic acids: ethyl acetate extraction/oxime-trimethylsilyl derivatization/GC-MS. Twenty-seven acids were quantified on the basis of specific ions in both scan and selected-ion monitoring modes. We found that the tuning of the mass detector severely affects the calibration factors, being critical to achieve quantitative results, and we propose a practical procedure for reproducible tuning. Of seven compounds tested, tropic acid was retained as the internal standard suitable for most of the acids of clinical interest; a second internal standard, 2-ketocaproic acid, was used in quantifying keto-acids. The within-day and total relative standard deviations (CVs), estimated from scan-mode analyses of urine, ranged from 2.6% to 12.7% and from 4.2% to 11.8%, respectively. Curvilinear relationships between analytical response and concentration were observed for most of the acids investigated.

Gas-chromatographic method of analysis for urinary organic acids. II. Description of the procedure, and its application to diagnosis of patients with organic acidurias.

1980 ◽  
Vol 26 (13) ◽  
pp. 1847-1853 ◽  
Author(s):  
K Tanaka ◽  
A West-Dull ◽  
D G Hine ◽  
T B Lynn ◽  
T Lowe
Keyword(s):  
Organic Acids ◽  
Chromatographic Method ◽  
Normal Subjects ◽  
Retention Indices ◽  
Organic Aciduria ◽  
Organic Acidurias ◽  
Urinary Organic Acids ◽  
Urinary Organic Acid Analysis ◽  
Gas Chromatographic Method ◽  
Extensive List

Abstract A gas-chromatographic method for urinary organic acid analysis is described, designed to be used routinely for the diagnosis of organic aciduria. It involves extraction of urine with ethyl acetate, dehydration of extract residues, and trimethylsilylation. Organic acids are identified by using an extensive list of retention indices published in the accompanying paper (this issue). Quantitative values are given for organic acids in urines from 50 ostensibly normal subjects. Typical chromatograms of urinary organic acids from patients with eight well-established organic acidurias are also shown.

Metabolic profiles of urinary organic acids recovered from absorbent filter paper.

1987 ◽  
Vol 33 (4) ◽  
pp. 572-576 ◽  
Author(s):  
B A Chamberlin ◽  
C C Sweeley
Keyword(s):  
Young Children ◽  
Organic Acids ◽  
Filter Paper ◽  
Metabolic Profiles ◽  
Sample Storage ◽  
Organic Acidurias ◽  
Urinary Organic Acids ◽  
Specimen Collection ◽  
Normal Urine

Abstract We evaluated for reliability and reproducibility a semiquantitative gas-chromatographic assay of organic acids in samples of normal urine recovered from absorbent filter paper. We also evaluated this method for use in diagnosis of some of the more common organic acidurias. Transfer of urine from diapers to absorbent filter paper eases the usual trauma of specimen collection from young children; it also simplifies sample storage and shipment.

Recommendations for urinary organic acids analysis

2020 ◽  
Vol 78 (5) ◽  
pp. 547-554
Author(s):  
Laetitia Van Noolen ◽  
Cécile Acquaviva-Bourdain ◽  
Anne-Frédérique Dessein ◽  
Régine Minet-Quinard ◽  
Marie Nowoczyn ◽  
...  
Keyword(s):  
Organic Acids ◽  
Urinary Organic Acids

METABOLIC EFFECTS OF THREE TESTOSTERONE DERIVATIVES INCLUDING 17α-ETHYL-19-NORTESTOSTERONE

1957 ◽  
Vol 16 (1) ◽  
pp. 28-40 ◽  
Author(s):  
R. R. McSWINEY ◽  
F. T. G. PRUNTY
Keyword(s):  
Nitrogen Retention ◽  
Urinary Calcium ◽  
Plasma Calcium ◽  
Metabolic Effects ◽  
Calcium Balance ◽  
Sodium Potassium ◽  
The Third ◽  
Calcium Phosphorus ◽  
Derivatives Of ◽  
Plasma Phosphorus

SUMMARY 1. The protein anabolic properties of three derivatives of testosterone have been investigated. 2. 17α-methyl-Δ5-androstene-3β: 17β-diol and 17α-methyl androstane-3α: 17β-diol produced nitrogen retention in doses approaching those reported as androgenic by other investigators. 3. The third compound, 17α-ethyl-19-nortestosterone (17-ENT), which was studied in greatest detail, produced nitrogen retention in moderate dosage. Other metabolic effects were a fall in urinary calcium and, usually, a fall in faecal calcium. Phosphorus balance agreed with that calculated from nitrogen and calcium balance. Plasma calcium showed no consistent variation, while plasma phosphorus fell. 17-ENT also brought about marked changes in weight, and in fluid, sodium, potassium and chloride balances which are probably due partly to the retention of nitrogen and corresponding intracellular fluid, and partly to increased sweating. When given to two patients with osteoporosis due to prolonged steroid therapy, and receiving prednisone, the compound appeared to aid the restoration of a positive calcium balance. 17-ENT was found to have definite androgenic effects, but their intensity requires further study.

Urinary organic acids in peroxisomal disorders: a simple screening method

2001 ◽  
Vol 758 (1) ◽  
pp. 81-86 ◽  
Author(s):  
Seiji Yamaguchi ◽  
Misako Iga ◽  
Masahiko Kimura ◽  
Yasuyuki Suzuki ◽  
Nobuyuki Shimozawa ◽  
...  
Keyword(s):  
Organic Acids ◽  
Screening Method ◽  
Peroxisomal Disorders ◽  
Urinary Organic Acids ◽  
Simple Screening
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