scholarly journals Comparison of apurinic DNA-binding protein from an ataxia telangiectasia and a HeLa cell line. Evidence for an altered processing of apurinic/apyrimidinic endonuclease.

1985 ◽  
Vol 260 (28) ◽  
pp. 14918-14924
Author(s):  
U Kuhnlein
Biochemistry ◽  
1994 ◽  
Vol 33 (47) ◽  
pp. 14185-14196 ◽  
Author(s):  
Christopher E. Pearson ◽  
Marcia T. Ruiz ◽  
Gerald B. Price ◽  
Maria Zannis-Hadjopoulos

1993 ◽  
Vol 268 (30) ◽  
pp. 22450-22455
Author(s):  
B Teale ◽  
K.K. Khanna ◽  
S.P. Singh ◽  
M.F. Lavin

2009 ◽  
Vol 44 (3) ◽  
pp. 150-153
Author(s):  
Roberto Ravazzolo ◽  
Giovanna Bianchi-Scarrǎ ◽  
Valeria Capra ◽  
Paola Fiorentini ◽  
Cecilia Garrě

2007 ◽  
Vol 342-343 ◽  
pp. 457-460 ◽  
Author(s):  
You Kyoung Kim ◽  
In Kyu Park ◽  
Hu Lin Jiang ◽  
Rohidas B. Arote ◽  
Hwan Jeong Jeong ◽  
...  

Polypropylenimine (PPI) dendrimers have been used by many researchers as gene delivery carriers due to their high functionality. Glucose as a kind of carbohydrate is biocompatible and hydrophilic. In this study, we synthesized glucosylated PPI (G-PPI) dendrimers to reduce cytotoxicity. Glucose substitution of G-PPI dendrimers was determined by the sulfuric acid micromethod. The G-PPI dendrimer was complexed with plasmid DNA in various N/P ratios, and the complex was characterized. G-PPI dendrimers showed good DNA binding ability and high protection of DNA from nuclease attack. The G-PPI dendrimer had low cytotoxicity compared to PPI dendrimer by cytotoxicity assay. Also, transfection efficiency was influenced by glucosylation degree and the transfection efficiency for the G-PPI-5 was slightly higher than that of PPI dendrimer in HeLa cell line.


2010 ◽  
Vol 222 (03) ◽  
Author(s):  
S Degen ◽  
S Kuhfittig-Kulle ◽  
JH Schulte ◽  
F Westermann ◽  
A Schramm ◽  
...  

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