scholarly journals The steady state concentrations of coenzyme A-SH and coenzyme A thioester, citrate, and isocitrate during tricarboxylate cycle oxidations in rabbit heart mitochondria.

1975 ◽  
Vol 250 (21) ◽  
pp. 8361-8375 ◽  
Author(s):  
RG Hansford ◽  
RN Johnson
Keyword(s):  
Steady State ◽  
Coenzyme A ◽  
Rabbit Heart ◽  
Heart Mitochondria ◽  
Tricarboxylate Cycle

scholarly journals Purification and Characteristics of a Butyryl Coenzyme A Synthetase from Bovine Heart Mitochondria

1965 ◽  
Vol 240 (1) ◽  
pp. 29-33
Author(s):  
Leslie T. Webster ◽  
Lance D. Gerowin ◽  
Louis Rakita
Keyword(s):  
Coenzyme A ◽  
Heart Mitochondria ◽  
Bovine Heart

Interaction of creatine kinase with phosphorylating rabbit heart mitochondria and mitoplasts

1986 ◽  
Vol 251 (2) ◽  
pp. 558-566 ◽  
Author(s):  
Christian Vial ◽  
Olivier Marcillat ◽  
Denise Goldschmidt ◽  
Bernard Font ◽  
Denise Eichenberger
Keyword(s):  
Creatine Kinase ◽  
Rabbit Heart ◽  
Heart Mitochondria

Active transport of potassium by heart mitochondria

1960 ◽  
Vol 198 (4) ◽  
pp. 847-854 ◽  
Author(s):  
Frank Ulrich
Keyword(s):  
Methylene Blue ◽  
Active Transport ◽  
Creatine Phosphate ◽  
Rabbit Heart ◽  
Potassium Transport ◽  
Heart Mitochondria ◽  
Metabolic Inhibitors ◽  
Mitochondrial Suspension ◽  
High Concentrations ◽  
Potassium Gradient

Rabbit heart mitochondria contained potassium which could not be removed with four washings of isotonic sucrose or sodium chloride at 0–4°C. Aging, increasing concentrations of potassium, and a number of metabolic poisons either partially or completely inhibited the active transport of potassium into heart mitochondria when these particles were incubated for 15 minutes in air at 37.4° in a medium to which alpha-ketoglutarate and AMP or ATP had been added. Compounds uncoupling oxidative phosphorylation—such as arsenite, 2,4-dinitrophenol, l-thyroxine, calcium chloride, dicumarol, pentachlorophenol and methylene blue—inhibited potassium transport but usually only at relatively high concentrations (10–3 m). With the exception of p-chloromercuribenzoate, neither aging nor metabolic inhibitors prevented the extrusion of water by the mitochondria in the presence of alpha-ketoglutarate and AMP or ATP. Although addition of either ATP or substrate alone to the mitochondrial suspension resulted in a significant increase in the potassium gradient, the latter was much greater when both substrate and ATP (or ADP or AMP) were added together. ADP or AMP alone caused a very slight but probably not significant increase in the potassium gradient and creatine phosphate had no effect.

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