484: Determination of the Maximum Safe Laparoscopic Warm Renal Ischemia Time in the Porcine Solitary Kidney Model

2004 ◽  
Vol 171 (4S) ◽  
pp. 129-129
Author(s):  
Lincoln J. Maynes ◽  
Kenneth A. Berger ◽  
Premal J. Desai ◽  
Craig Zuppan ◽  
Ada Winkielman ◽  
...  
2008 ◽  
Vol 16 (1) ◽  
pp. 105-109 ◽  
Author(s):  
Mitchell R Humphreys ◽  
Erik P Castle ◽  
Christine M Lohse ◽  
Thomas J Sebo ◽  
Kevin O Leslie ◽  
...  

2020 ◽  
Vol 10 (6) ◽  
pp. 6718-6727 ◽  

Cardiac abnormalities and dysfunction are the most important complications after renal ischemia-reperfusion (IR). Thus, investigation and development of effective treatment to decrease cardiac damage induced by renal ischemia are necessary. This study examined the effects of treatment with calcitriol and erythropoietin (EPO) on cardiac injury induced by renal ischemia. Wistar albino rats were unilaterally nephrectomized and subjected to 45 min of renal pedicle occlusion, followed by 24 h reperfusion. Calcitriol and EPO were administered before ischemia. After 24 h reperfusion, blood samples were collected for the determination of biochemical parameters, and kidney and cardiac samples were taken for histological studies. Renal IR increased BUN-Cr levels, lipid profiles, and myocardial injury markers (CK-MB and LDH). Histopathological findings of the IR group confirmed that there were glomerular atrophy and acute tubular necrosis in the renal tissues and lymphocyte infiltration and intercellular edema in the cardiac samples. Treatment with calcitriol and EPO boosted cardiac and renal functions and improved the morphological changes. It seems that calcitriol or EPO administration could protect against the kidney and cardiac damage induced by IR. Also, the combination of calcitriol and EPO may exert more beneficial effects than either agent used alone.


Urology ◽  
2007 ◽  
Vol 70 (3) ◽  
pp. 106
Author(s):  
S. Tyritzis ◽  
A. Kyroudi ◽  
K. Pavlakis ◽  
T. Manousakas ◽  
M. Zachariades ◽  
...  

Urology ◽  
2007 ◽  
Vol 69 (2) ◽  
pp. 402-406 ◽  
Author(s):  
Mark B. Lyon ◽  
Marcelo A. Orvieto ◽  
Kevin C. Zorn ◽  
Stephen R. Tolhurst ◽  
David E. Rapp ◽  
...  

1988 ◽  
Vol 45 (1) ◽  
pp. 147-152 ◽  
Author(s):  
Jos G. Maessen ◽  
Ger J. van der Vusse ◽  
Michael Vork ◽  
Will A. Coumans ◽  
Gauke Kootstra
Keyword(s):  

2019 ◽  
Vol 86 (5) ◽  
pp. 68-71 ◽  
Author(s):  
D. I. Кuprin ◽  
А. I. Boyko ◽  
N. О. Saidakova ◽  
А. О. Gubar

Objective. To analyze the cases histories of urolithiasis disease and its course peculiarities in patients with a solitary kidney, unilateral urolithiasis and concomitant diabetes mellitus type II. Маterials and methods. Retrospective analysis of the cases histories was conducted in 109 patients, suffering urolithiasis disease with concomitant diabetes mellitus type II, of them in 31 patients a solitary kidney was present (Group I), in 78 - unilateral nephrolithiasis (Group II). Results. There was established, that even in adequately corrected hyperglycemia in the patients, having a solitary kidney, the risk for unfavorable course of urolithiasis disease and diabetes mellitus type II is higher, than in patients, having both functioning kidneys. The majority of patients, having a solitary kidney, owe the lowered velocity indices of glomerular filtration and glomerular hyperfiltration, proteinuria and arterial hypertension, what, even in presence of diabetes mellitus with the middle severity course, constitutes a high risk for rapid lowering of renal function. Conclusion. In the urolithiasis disease in the patients with a solitary kidney and concomitant diabetes mellitus type II there have an objectively proven risk for progressing of chronic renal disease. The necessity for the multidisciplinary approach realization of the urologists and endocrinologists activities in determination of personified schemes of treatment in these patients is substantiated.


BMC Surgery ◽  
2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Liu Zhuo ◽  
Zhu Guodong ◽  
Zhao Xun ◽  
Tang Shiying ◽  
Hong Peng ◽  
...  

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