Kinetic study of microwave-assisted Wittig reaction of stabilised ylides with aromatic aldehydes

2001 ◽  
Vol 42 (39) ◽  
pp. 6827-6829 ◽  
Author(s):  
Sara Frattini ◽  
Monica Quai ◽  
Enzo Cereda
Author(s):  
Hadis Khodadad ◽  
Farhad Hatamjafari ◽  
Khalil Pourshamsian ◽  
Babak Sadeghi

Aim and Objective: Microwave-assisted condensation of acetophenone 1 and aromatic aldehydes 2 gave chalcone analogs 3, which were cyclized to pyrazole derivatives 6a-f via the reaction with hydrazine hydrate and oxalic acid in the presence of the catalytic amount of acetic acid in ethanol. Materials and Methods: The structural features of the synthesized compounds were characterized by melting point, FT-IR, 1H, 13C NMR and elemental analysis. Results: The antibacterial activities of the synthesized pyrazoles was evaluated against three gram-positive bacteria such as Enterococcus durans, Staphylococcus aureus, Bacillus subtilis and two gram-negative bacteria such as Escherichia coli and Salmonella typhimurium. Conclusion: All the synthesized pyrazoles showed relatively high antibacterial activity against S. aureus strain and none of them demonstrated antibacterial activity against E. coli.


ACS Omega ◽  
2017 ◽  
Vol 2 (8) ◽  
pp. 5196-5208 ◽  
Author(s):  
Regina C. So ◽  
Jemimah E. Sanggo ◽  
Lei Jin ◽  
Jose Mario A. Diaz ◽  
Raphael A. Guerrero ◽  
...  

2013 ◽  
Vol 50 (S1) ◽  
pp. E189-E192 ◽  
Author(s):  
Eugene S. Gladkov ◽  
Sergey M. Desenko ◽  
Irina S. Konovalova ◽  
Ulrich Groth ◽  
Oleg V. Shishkin ◽  
...  

2016 ◽  
Author(s):  
Nur’aini Raman Yusuf ◽  
Ruzaimah Nik Mohamad Kamil ◽  
Suzana Yusup

Sign in / Sign up

Export Citation Format

Share Document