Direct Action of Atropine on the Cerebral Cortex of the Rabbit

1965 ◽  
pp. 229-244 ◽  
Author(s):  
F. Rinaldi
Keyword(s):  
Cerebral Cortex ◽  
Direct Action

On Certain Acute Secondary Visceral Lesions in the Insane

1882 ◽  
Vol 27 (120) ◽  
pp. 600-601
Author(s):  
E. Dufour
Keyword(s):  
Cerebral Cortex ◽  
Foreign Bodies ◽  
Direct Action ◽  
Central Nuclei ◽  
The Brain ◽  
Mechanical Irritation ◽  
At Will

In a paper in the “Annales Médico-Psychologiques,” for July, 1876, Dr. Dufour showed the existence of numerous secondary visceral lesions in certain cases. Now experiments by various physiologists have proved that these lesions can be produced at will in animals by pricking or tearing certain regions of the brain, such as the peduncles, &c., in which irritation by foreign bodies causes various disorders of the pleurae, lungs, liver, kidneys, stomach, intestines, &c. Further, some facts seem to prove that the same changes may follow mechanical irritation of the periphery of the cerebral organs. Are these results due to a direct action, or to transmission to the central nuclei ? The question is difficult of solution, but the fact remains. Do not the phenomena of émotivité, which have their seat in the cerebral cortex, react in the same manner upon the splanchnic organs.

Role of local neurons in cerebrocortical vasodilation elicited from cerebellum

1987 ◽  
Vol 252 (6) ◽  
pp. R1082-R1091 ◽  
Author(s):  
C. Iadecola ◽  
S. P. Arneric ◽  
H. D. Baker ◽  
L. W. Tucker ◽  
D. J. Reis
Keyword(s):  
Cerebral Cortex ◽  
Direct Action ◽  
Neuronal Loss ◽  
Blood Gases ◽  
Ibotenic Acid ◽  
Co2 Partial Pressure ◽  
Primary Sensory Cortex ◽  
Afferent Fibers ◽  
Alpha Chloralose

The vasodilation elicited in cerebral cortex by stimulation of the cerebellar fastigial nucleus (FN) is mediated by input pathways coming from the basal forebrain. We studied whether these pathways mediate the cortical vasodilation via a direct action on local blood vessels or via interposed local neurons. Neurons were destroyed in the primary sensory cortex by local microinjection of the excitotoxin ibotenic acid (IBO) (10 micrograms/l microliter). Five days later rats were anesthetized (alpha-chloralose), paralyzed, and ventilated. Arterial pressure and blood gases were controlled, and FN was stimulated electrically. Local cerebral blood flow (LCBF) was measured using the [14C]iodoantipyrine technique with autoradiography. Five days after IBO, neurons were destroyed in a restricted cortical area, and afferent fibers and terminals were preserved. The selectivity of the neuronal loss was established by histological and biochemical criteria and by transport of horseradish peroxidase from or into the lesion. Within the lesion, resting LCBF (n = 7) was unaffected, but the increase in LCBF evoked from the FN was abolished (P greater than 0.05); n = 6). In contrast the vasodilation elicited by hypercapnia (arterial CO2 partial pressure = 62.7 +/- 3; n = 5) was preserved. In the rest of the brain the vasodilation elicited from FN was largely unaffected. We conclude that the vasodilation evoked from FN in cerebral cortex depends on the integrity of a restricted population of local neurons that interact with the local microvasculature.

Author response for "Microchiropterans have a diminutive cerebral cortex, not an enlarged cerebellum, compared to megachiropterans and other mammals"

2020 ◽  
Author(s):  
Suzana Herculano‐Houzel ◽  
Felipe Barros Cunha ◽  
Jamie L. Reed ◽  
Consolate Kaswera‐Kyamakya ◽  
Emmanuel Gillissen ◽  
...  
Keyword(s):  
Cerebral Cortex ◽  
Author Response

Oligodendrocytes in Developing Hameter Cerebral Cortex

1976 ◽  
Vol 34 ◽  
pp. 126-127
Author(s):  
MB. Tank Buschmann
Keyword(s):  
Cerebral Cortex ◽  
Optic Nerve ◽  
Frontal Cortex ◽  
Osmium Tetroxide ◽  
Sodium Cacodylate Buffer ◽  
Sodium Cacodylate ◽  
Tissue Samples ◽  
Cacodylate Buffer ◽  
Layer V ◽  
Adult Hamster

Development of oligodendrocytes in rat corpus callosum was described as a sequential change in cytoplasmic density which progressed from light to medium to dark (1). In rat optic nerve, changes in cytoplasmic density were not observed, but significant changes in morphology occurred just prior to and during myelination (2). In our study, the ultrastructural development of oligodendrocytes was studied in newborn, 5-, 10-, 15-, 20-day and adult frontal cortex of the golden hamster (Mesocricetus auratus).Young and adult hamster brains were perfused with paraformaldehyde-glutaraldehyde in sodium cacodylate buffer at pH 7.3 according to the method of Peters (3). Tissue samples of layer V of the frontal cortex were post-fixed in 2% osmium tetroxide, dehydrated in acetone and embedded in Epon-Araldite resin.

Glucuronyl 3-sulfate occurs exclusively on distal unmyelinated terminals of selected sensory neurons in the peripheral nervous system

1995 ◽  
Vol 53 ◽  
pp. 958-959
Author(s):  
S.S. Spicer ◽  
B.A. Schulte
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Cerebral Cortex ◽  
Peripheral Nervous System ◽  
Sensory Neurons ◽  
Sensory Nerves ◽  
Tissue Antigens ◽  
The Central Nervous System ◽  
The Brain ◽  
Leu 7

Generation of monoclonal antibodies (MAbs) against tissue antigens has yielded several (VC1.1, HNK- 1, L2, 4F4 and anti-leu 7) which recognize the unique sugar epitope, glucuronyl 3-sulfate (Glc A3- SO4). In the central nervous system, these MAbs have demonstrated Glc A3-SO4 at the surface of neurons in the cerebral cortex, the cerebellum, the retina and other widespread regions of the brain.Here we describe the distribution of Glc A3-SO4 in the peripheral nervous system as determined by immunostaining with a MAb (VC 1.1) developed against antigen in the cat visual cortex. Outside the central nervous system, immunoreactivity was observed only in peripheral terminals of selected sensory nerves conducting transduction signals for touch, hearing, balance and taste. On the glassy membrane of the sinus hair in murine nasal skin, just deep to the ringwurt, VC 1.1 delineated an intensely stained, plaque-like area (Fig. 1). This previously unrecognized structure of the nasal vibrissae presumably serves as a tactile end organ and to our knowledge is not demonstrable by means other than its selective immunopositivity with VC1.1 and its appearance as a densely fibrillar area in H&E stained sections.

Visual Spatial Attention in Migraine Sufferers in Postictal and Interictal Phases: An Event-Related Potential Study

2001 ◽  
Vol 15 (1) ◽  
pp. 22-34 ◽  
Author(s):  
D.H. de Koning ◽  
J.C. Woestenburg ◽  
M. Elton
Keyword(s):  
Cerebral Cortex ◽  
Visual Attention ◽  
Migraine Attack ◽  
Spatial Attention ◽  
Event Related Potential ◽  
Significant Enhancement ◽  
Pathophysiological Mechanism ◽  
Attention Task ◽  
Visual Spatial Attention ◽  
Visual Spatial

Migraineurs with and without aura (MWAs and MWOAs) as well as controls were measured twice with an interval of 7 days. The first session of recordings and tests for migraineurs was held about 7 hours after a migraine attack. We hypothesized that electrophysiological changes in the posterior cerebral cortex related to visual spatial attention are influenced by the level of arousal in migraineurs with aura, and that this varies over the course of time. ERPs related to the active visual attention task manifested significant differences between controls and both types of migraine sufferers for the N200, suggesting a common pathophysiological mechanism for migraineurs. Furthermore, migraineurs without aura (MWOAs) showed a significant enhancement for the N200 at the second session, indicating the relevance of time of measurement within migraine studies. Finally, migraineurs with aura (MWAs) showed significantly enhanced P240 and P300 components at central and parietal cortical sites compared to MWOAs and controls, which seemed to be maintained over both sessions and could be indicative of increased noradrenergic activity in MWAs.

The Cerebral Cortex in English

1960 ◽  
Vol 5 (11) ◽  
pp. 374, 376
Author(s):  
A. EARL WALKER
Keyword(s):  
Cerebral Cortex
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