Re-emergence of Chlamydia trachomatis Infection After Mass Antibiotic Treatment of a Trachoma-Endemic Gambian Community: A Longitudinal Study

2006 ◽  
Vol 2006 ◽  
pp. 117
Author(s):  
B.H. Thiers
The Lancet ◽  
2005 ◽  
Vol 365 (9467) ◽  
pp. 1321-1328 ◽  
Author(s):  
Matthew J Burton ◽  
Martin J Holland ◽  
Pateh Makalo ◽  
Esther AN Aryee ◽  
Neal DE Alexander ◽  
...  

2020 ◽  
Vol 80 (4) ◽  
pp. 454-461
Author(s):  
Robert Butcher ◽  
Becca Handley ◽  
Mackline Garae ◽  
Raebwebwe Taoaba ◽  
Harry Pickering ◽  
...  

2019 ◽  
Vol 221 (4) ◽  
pp. 627-635 ◽  
Author(s):  
Jeanne Tamarelle ◽  
Bing Ma ◽  
Pawel Gajer ◽  
Mike S Humphrys ◽  
Mishka Terplan ◽  
...  

Abstract We characterized the composition and structure of the vaginal microbiota in a cohort of 149 women with genital Chlamydia trachomatis infection at baseline who were followed quarterly for 9 months after antibiotic treatment. At time of diagnosis, the vaginal microbiota was dominated by Lactobacillus iners or a diverse array of bacterial vaginosis–associated bacteria including Gardnerella vaginalis. Interestingly, L. iners–dominated communities were most common after azithromycin treatment (1 g monodose), consistent with the observed relative resistance of L. iners to azithromycin. Lactobacillus iners–dominated communities have been associated with increased risk of C. trachomatis infection, suggesting that the impact of antibiotic treatment on the vaginal microbiota could favor reinfections. These results provide support for the dual need to account for the potential perturbing effect(s) of antibiotic treatment on the vaginal microbiota, and to develop strategies to protect and restore optimal vaginal microbiota.


2016 ◽  
Vol 10 (10) ◽  
pp. e0005080 ◽  
Author(s):  
Athumani M. Ramadhani ◽  
Tamsyn Derrick ◽  
David Macleod ◽  
Martin J. Holland ◽  
Matthew J. Burton

2013 ◽  
Vol 89 (Suppl 1) ◽  
pp. A156.1-A156
Author(s):  
T Bharara ◽  
D Rawat ◽  
P Bhalla ◽  
V K Garg ◽  
K Sardana ◽  
...  

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