International standards for newborn weight, length, and head circumference by gestational age and sex: the Newborn Cross-Sectional Study of the INTERGROWTH-21st Project

The Lancet ◽  
2014 ◽  
Vol 384 (9946) ◽  
pp. 857-868 ◽  
Author(s):  
José Villar ◽  
Leila Cheikh Ismail ◽  
Cesar G Victora ◽  
Eric O Ohuma ◽  
Enrico Bertino ◽  
...  
2020 ◽  
Vol 7 (8) ◽  
pp. 414-419
Author(s):  
Dr. Abhinaya Arun Raj ◽  
◽  
Dr. K. Maheswari ◽  

Introduction: This study was done to assess the utility of foot length in determining theanthropometric parameters of a newborn in a tertiary care teaching hospital. Materials andMethods: This cross-sectional study among 270 newborns were done at Sri Venkateswaraa medicalcollege hospital and research centre, from Nov 2018 to May 2020. All the healthy live newbornswere taken into the study and newborns with congenital lower limb anomalies were excluded.Results: The mean birth weight of the neonate 2.948+0.344 kg which ranged from 2.050 kg to3.750kg. The mean foot length, head circumference and chest circumference of the foot length was8.113+0.468 cm, 48.989+1.093 cm, 34.437+0.659 cm and 32.372+0.734 cm respectively. The footlength had a maximum correlation with birth weight (r-value=0.905) followed by gestational age (r-value=0.809), length (r-value=0.786), head circumference (r-value=0.719) and chest circumference(r-value=0.603). Conclusion: Foot length had a significant correlation with birth weight andgestational age of the neonates. Foot length also correlated significantly with other anthropometricvariables like length, head circumference and chest circumference.


2021 ◽  
Vol 8 (2) ◽  
pp. 109-115
Author(s):  
Dr. Vishal Shrivastava ◽  
◽  
Dr. Purnendu Shekhar Lohia ◽  
Ms. Anita Sahu ◽  
◽  
...  

Introduction: Preterm birth is the leading cause of death in children younger than 5 yearsworldwide. Although preterm survival rates have increased in high-income countries, pretermnewborns still die because of a lack of adequate newborn care in many low-income and middle-income countries. This study was aimed to find out the effectiveness of anthropometricmeasurement, a simple and inexpensive method, for identifying premature babies at birth. Method:We conducted a cross-sectional study in a tertiary care hospital with 350 consecutively live-bornnewborns. Their birth weight, mid-arm circumference, length and head circumference weremeasured and compared with gestational age assessed by New Ballard score. We summarized thevariables using descriptive statistics, and the strength of association was determined throughcorrelation analysis. The correlation was strong for head circumference. Linear regression analysiswas done to develop predictive equations. Result: Amongst 350 newborns, 76% were term and24% were preterm. Pearson's correlation coefficient between gestational age as assessed by NewBallard score and head circumference, birth weight, mid-arm circumference and length all showed asignificant positive correlation in the decreasing order [maximum with head circumference (r =0.566)]. Linear regression analysis was done to develop predictive equations. Conclusion: Headcircumference measurement can be a surrogate marker to predict prematurity as a significantcorrelation is seen between it and gestational age assessed by the New Ballard score. Furtherstudies are needed to cross-validate our result.


Author(s):  
Ananya S. L. Tenali ◽  
Ravi Kumar Tenali

Background: India is one of the countries with the highest neonatal mortality, for which preterm birth is considered as major cause (43.7%). Therefore, early identification by a simple screening tool is important for prognostication and follow-up of new-born infants, especially preterm.Methods: Cross-sectional study was conducted on 300 live newborns at Saveetha Hospital in Kanchipuram. Anthropometric measures such as birth weight, crown-heel length, head circumference, foot length were taken within 3 days of life and gestational age assessment was done by new Ballard scoring after calculation by Naegles formula. Neonates were grouped into preterm, term and post-term and also small for gestational age (SGA), appropriate for gestational age (AGA) and large for gestational age (LGA). Minimum to maximum range of variables in each gestational range was calculated. The sensitivity and specificity of each variable was found using receiver operating curve. Parameter having the highest sensitivity and good specificity was considered as potential screening tool to identify high risk babies. SPSS Software version 17 for windows was used.Results: The range of gestational age, length, foot length, birth weight and head circumference was 28-42 weeks, 35-53 cm, 5-8.8 cm, 0.8-4.7 kg and 22.8-54.3 cm respectively. Among all, maximum sensitivity at 37weeks gestational age was seen with foot length (80.57%) at a cut-off of 7.58 cm. A nomogram of foot length for each gestational age group (range of 2 weeks) was also derived.Conclusions: It can be concluded that foot length has the potential to be considered as a screening tool to identify preterm neonates especially at a concentrated community level and is particularly useful in resource constraint countries.


2020 ◽  
Vol 40 (3) ◽  
pp. 217-223
Author(s):  
Anju Kapoor ◽  
Triloki Nath Soni

Introduction: Neonatal mortality is higher in premature babies, more so when identification and intervention is delayed. This study was aimed to find out the effectiveness of foot length measurement, a simple and inexpensive method, for identifying premature babies at birth. Methods: This cross sectional study was conducted on 514 hospital born neonates. Their foot length, birth weight, length and head circumference were measured and compared with gestational age assessed by new Ballard score. Results: Amongst 514 newborns, 71.6% were term and 28.4% were preterm. Mean foot length in term and pre-term babies were 7.30 cm (SD + 0.39) and 6.81 cm (SD + 0.52) respectively (p value < 0.0001). Pearson's correlation coefficient between gestational age as assessed by new Ballard score and foot length, birth weight, length and head circumference all showed significant positive correlation in the decreasing order  [maximum with foot length (r = 0.802)]. Linear regression analysis for gestational age with foot length also had highest coefficient of determination R2 = 0.760 (P < 0.001). Foot length with cut-off < 6.83 cm has higher AUC (Area Under Curve) and is a good marker for predicting prematurity with a sensitivity of 94.57%, and a specificity of 41.99%. Conclusions: Foot length measurement can be a good surrogate marker to predict prematurity as significant correlation is seen between it and gestational age assessed by new Ballard score.


Author(s):  
Premlata Mital ◽  
Richa Ainani ◽  
Nupur Hooja ◽  
Priya Sonkhya ◽  
Vishwas Pradodh ◽  
...  

Background: Accurate knowledge of gestational age of the foetus is essential for planning a timely and uneventful outcome. Biparietal diameter, head circumference, abdominal circumference and femur length reliably predict gestational age. The humerus length is not widely used as biometric parameter for determining the GA so the present study was done to estimate foetal gestational age by measuring humerus length between 18 to 36 weeks of normal singleton pregnancies and to compare humerus length with routine parameters.Methods: This was a hospital based descriptive cross-sectional study, 200 women with viable singleton pregnancy, with known LMP, between 18 weeks to 36 weeks of gestation were included. Various foetal measurements such as biparietal diameter, head circumference, abdominal circumference, femur length and humerus length were measured using electronic calipers on ultrasound. Data were statistically analyzed.Results: The mean humerus length at 18 weeks was 25.27±1.16 mm and at 36 weeks of gestation was 57.11±1.58 mm. Simple linear regression analysis shows a strongly significant linear relationship between humerus length and gestational age. Where, gestational age (weeks) Y= 0.5213 x humerus length (X) + 4.905; with high degree of correlation coefficient (R2 =0.9785 and P≤0.0001). When Compared with BPD, HC, AC and FL, humerus length also shows a linear correlation.Conclusions: The measurement of the humerus length can be an important additional parameter for estimating gestational age along with other parameters and can be used to predict the gestational age of fetuses in special circumstances.


2020 ◽  
Vol 79 (Suppl 1) ◽  
pp. 1509.1-1510
Author(s):  
T. Klein ◽  
S. Tiosano ◽  
A. Chohen ◽  
H. Amital

Background:Systemic Lupus Erythematosus (SLE) is a chronic autoimmune disease characterized by multisystem inflammatory lesions affecting many organ systems in the body. Familial Mediterranean fever (FMF) is an autosomal recessive disease of chronic autoimmune inflammation characterized by frequently relapsing self-limiting fever and inflammation that may be localized in peritoneum, pleura, joint or skin.1Previous studies have described the similarity of clinical symptoms of FMF among SLE patients. However, the literature on this topic is inconsistent and based mostly on case reports.2-4Objectives:To examine the proportions of coexistence of FMF among SLE patients compared to the general population. We hypothesized that the proportion of FMF among SLE patients is higher than the general population.Methods:This cross-sectional study used the Clalit Health Services database, the largest Health Maintenance Organization in Israel, serving 4,400,000 members. SLE patients were compared to age- and sex-matched controls. Chi- was used for univariate analysis.Results:The study included4886 SLEpatients and 24430 age- and sex-matched controls. The SLE group had a significantly higher proportion of FMF patients compared to non-SLE controls (0.68% and 0.21% respectively; p < 0.001).Table 1. All study populationTable 1.SLE patients and matched controls basic characteristicsNo SLESLEp.overallN=24430N=4886Age51.2±16.551.2±16.51.000Gender: Female20100 (82.3%)4020 (82.3%)1.000FMF52 (0.21%)33 (0.68%)<0.001Table 2. StratificationTable 2.comparison of FMF patients with and without SLEFMF without SLEFMF with SLEp.overallN=52N=33Age44.6±13.750.5±17.70.106Gender: Female45 (86.5%)26 (78.8%)0.523Conclusion:FMF was found to be more common amongst SLE patients compared to matched controls.The current study results suggest that the occurrence of SLE turn patients with an appropriate genetic and environmental setting to develop also FMF. This cross-sectional study sheds light on the coexistence of these two diseases, autoimmune and autoinflammatory.References:[1]Kucuk A, Gezer IA, Ucar R, Karahan AY. Familial mediterranean fever.Acta Medica (Hradec Kralove). 2014;57(3):97-104.[2]Lidar M, Zandman-Goddard G, Shinar Y, Zaks N, Livneh A, Langevitz P. SLE and FMF: A possible negative association between the two disease entities–report of four cases and review of the literature.Lupus. 2008;17(7):663-669.[3]Erten S, Taskaldiran I, Yakut ZI. Are systemic lupus erythematosus patients carrying MEFV gene less prone to renal involvement? report of three cases and review of the literature.Ren Fail. 2013;35(7):1013-1016.[4]Shinar Y, Kosach E, Langevitz P, et al. Familial mediterranean Fever gene (MEFV) mutations as a modifier of systemic lupus erythematosus.Lupus. 2012;21(9):993-998.Disclosure of Interests: :None declared


2021 ◽  
Vol 8 ◽  
pp. 2333794X2110196
Author(s):  
Sitotaw Molla Mekonnen ◽  
Daniel Mengistu Bekele ◽  
Fikrtemariam Abebe Fenta ◽  
Addisu Dabi Wake

Necrotizing enterocolitis (NEC) remains to be the most critical and frequent gastrointestinal disorder understood in neonatal intensive care units (NICU). The presented study was intended to assess the prevalence of NEC and associated factors among enteral Fed preterm and low birth weight neonates. Institution based retrospective cross-sectional study was conducted on 350 enteral Fed preterm and low birth weight neonates who were admitted at selected public hospitals of Addis Ababa from March 25/2020 to May 10/2020. The data were collected through neonates’ medical record chart review. A total of 350 participants were enrolled in to the study with the response rate of 99.43%. One hundred eighty-four (52.6%) of them were male. The majority 123 (35.1%) of them were (32 + 1 to 34) weeks gestational age. The prevalence of NEC was (25.4%) (n = 89, [95% CI; 21.1, 30.0]). Being ≤28 weeks gestational age (AOR = 3.94, 95% CI [2.67, 9.97]), being (28 + 1 to 32 weeks) gestational age (AOR = 3.65, 95% CI [2.21, 8.31]), birth weight of 1000 to 1499 g (AOR = 2.29, 95% CI [1.22, 4.33]), APGAR score ≤3 (AOR = 2.34, 95% CI [1.32, 4.16]), prolonged labor (AOR = 2.21, 95% CI [1.35, 6.38]), maternal chronic disease particularly hypertension (AOR = 3.2, 95% CI [1.70, 5.90]), chorioamnionitis (AOR = 4.8, 95% CI [3.9, 13]), failure to breath/resuscitated (AOR = 2.1, 95% CI [1.7, 4.4]), CPAP ventilation (AOR = 3.7, 95% CI [1.50, 12.70]), mixed milk (AOR = 3.58, 95% CI [2.16, 9.32]) were factors significantly associated with NEC. Finally, the prevalence of NEC in the study area was high. So that, initiating the programs that could minimize this problem is required to avoid the substantial morbidity and mortality associated with NEC.


Author(s):  
Margit Steinholt ◽  
Shanshan Xu ◽  
Sam Ol Ha ◽  
Duong Trong Phi ◽  
Maria Lisa Odland ◽  
...  

We conducted a cross-sectional study among 194 pregnant women from two low-income settings in Cambodia. The inclusion period lasted from October 2015 through December 2017. Maternal serum samples were analyzed for persistent organic pollutants (POPs). The aim was to study potential effects on birth outcomes. We found low levels of polychlorinated biphenyls (PCBs) and organochlorine pesticides (OCP), except for heptachlors, β-hexachlorocyclohexane (HCH), heptachlor epoxide, and p,p’-DDE. There were few differences between the two study locations. However, the women from the poorest areas had significantly higher concentrations of p,p’-DDE (p < 0.001) and hexachlorobenzene (HCB) (p = 0.002). The maternal factors associated with exposure were parity, age, residential area, and educational level. Despite low maternal levels of polychlorinated biphenyls, we found significant negative associations between the PCB congeners 99 (95% CI: −2.51 to −0.07), 138 (95% CI: −1.28 to −0.32), and 153 (95% CI: −1.06 to −0.05) and gestational age. Further, there were significant negative associations between gestational age, birth length, and maternal levels of o,p’-DDE. Moreover, o,p’-DDD had positive associations with birth weight, and both p,p’-DDD and o,p’-DDE were positively associated with the baby’s ponderal index. The poorest population had higher exposure and less favorable outcomes.


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