Isolation and N-terminal sequence determination of a novel γ/δ T cell surface antigen

1997 ◽  
Vol 34 (8-9) ◽  
pp. 583-591
Author(s):  
Naushaba Nayeem ◽  
Patrick J. Barker ◽  
Richard M. Binns ◽  
J. Kanan ◽  
Benjamin Chain
1987 ◽  
Vol 165 (6) ◽  
pp. 1743-1748 ◽  
Author(s):  
M F Heyworth ◽  
J R Carlson ◽  
T H Ermak

The aim of this work was to identify the T cell subset (helper/inducer or cytotoxic/suppressor) that plays a major part in the clearance of Giardia muris infection. BALB/c mice were selectively depleted of helper/inducer (Th/i) or cytotoxic/suppressor (Tc/s) T cells, by treatment with rat IgG monoclonal antibodies directed against the Th/i cell surface antigen L3T4, or against the Tc/s cell surface antigen Ly-2, and were infected with G. muris cysts. While mice depleted of Tc/s cells cleared G. muris infection at a normal rate, mice depleted of Th/i cells did not clear the infection. Depletion of the relevant T cell subset was confirmed by flow cytometry and by immunohistochemistry. The data indicate that helper/inducer T cells, but not cytotoxic T cells, are of major importance for elimination of G. muris from the mouse intestine.


1987 ◽  
Vol 105 (1) ◽  
pp. 161-173 ◽  
Author(s):  
Hans Yssel ◽  
Jan E. De Vries ◽  
Jannie Borst ◽  
Hergen Spits

1990 ◽  
Vol 37 (1-10) ◽  
pp. 9-18 ◽  
Author(s):  
Hiroyuki Koyama ◽  
Masato Kozakai ◽  
Satosi Kunita ◽  
Tsutomu Hohdatsu ◽  
Tomohide Nasu ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document