Evaluation of the total content of lipid-soluble antioxidants in blood plasma samples employing a simple chemiluminescence quenching procedure

RNA analytical platforms gained extensive attention recently for RNA-based molecular analysis. However, the major challenge for analyzing RNAs is their low concentration in blood plasma samples, hindering the use of RNAs for diagnostics. Platforms that can enrich RNAs are essential to enhance molecular detection. Here, we developed the annealed ZnO/Al2O3 core-shell nanowire device as a platform to capture RNAs. We showed that the annealed ZnO/Al2O3 core-shell nanowire could capture RNAs with high efficiency compared to that of other circulating nucleic acids, including genomic DNA (gDNA) and cell-free DNA (cfDNA). Moreover, the nanowire was considered to be biocompatible with blood plasma samples due to the crystalline structure of the Al2O3 shell which serves as a protective layer to prevent nanowire degradation. Our developed device has the potential to be a platform for RNA-based extraction and detection.

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Disposable Carbon Electrodes for Liquid Chromatographic Detection of Catecholamines in Blood Plasma Samples

Electroanalysis ◽

10.1002/elan.200900334 ◽

2010 ◽

Vol 22 (3) ◽

pp. 325-332 ◽

Cited By ~ 11

Author(s):

Pranathi R. Perati ◽

Jun Cheng ◽

Petr Jandik ◽

Valoran P. Hanko

Keyword(s):

Blood Plasma ◽

Carbon Electrodes ◽

Plasma Samples ◽

Chromatographic Detection ◽

Liquid Chromatographic ◽

In Blood Plasma

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Detection of HIV-1 RNA in seminal plasma samples from treated patients with undetectable HIV-1 RNA in blood plasma

AIDS ◽

10.1097/qad.0b013e32830abdc8 ◽

2008 ◽

Vol 22 (13) ◽

pp. 1677-1679 ◽

Cited By ~ 76

Author(s):

Anne-Geneviève Marcelin ◽

Roland Tubiana ◽

Sidonie Lambert-Niclot ◽

Gilles Lefebvre ◽

Stéphanie Dominguez ◽

...

Keyword(s):

Blood Plasma ◽

Seminal Plasma ◽

Plasma Samples ◽

Hiv 1 ◽

In Blood Plasma

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Lipid Peroxide–Mediated Oxidative Rearrangement of the Pyrazinone Carboxamide Core of Neutrophil Elastase Inhibitor AZD9819 in Blood Plasma Samples

Drug Metabolism and Disposition ◽

10.1124/dmd.115.065136 ◽

2015 ◽

Vol 43 (10) ◽

pp. 1441-1449 ◽

Cited By ~ 2

Author(s):

Chungang Gu ◽

Richard J. Lewis ◽

Andrew S. Wells ◽

Per H. Svensson ◽

Vinayak P. Hosagrahara ◽

...

Keyword(s):

Blood Plasma ◽

Neutrophil Elastase ◽

Lipid Peroxide ◽

Plasma Samples ◽

Neutrophil Elastase Inhibitor ◽

Elastase Inhibitor ◽

Oxidative Rearrangement ◽

In Blood Plasma

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THE IMMEDIATE RESPONSE OF THE PLASMA PROLACTIN LEVEL TO OESTROGEN INFUSIONS IN DAIRY COWS

Acta Endocrinologica ◽

10.1530/acta.0.0690047 ◽

1972 ◽

Vol 69 (1) ◽

pp. 47-52 ◽

Cited By ~ 16

Author(s):

D. Schams ◽

H. Karg

Keyword(s):

Blood Plasma ◽

Dairy Cows ◽

Prolactin Level ◽

Fold Increase ◽

Plasma Prolactin ◽

Plasma Samples ◽

Subsequent Increase ◽

Plasma Prolactin Level ◽

Immediate Response ◽

In Blood Plasma

ABSTRACT Prolactin in blood plasma samples obtained from cows was determined by radioimmunoassay. During infusion of 2 mg or 4 mg 17β-oestradiol/hour there was a depression of the prolactin level, which seemed to be pronounced during infusions of 6 or 12 mg 17β-oestradiol/3 hours. In the experiments in which 2-6 mg 17β-oestradiol were administered a 2-5 fold increase in the plasma prolactin concentrations occurred after the infusions were completed. In the experiment with 12 mg 17β-oestradiol the depression was sustained for 3 hours after infusion; the subsequent increase the next few hours was comparatively small.

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