OC-0096 Does inter-observer variation affect functional imaging quantification in DW-MRI for HNSCC?

Abstract. Coronary artery disease (CAD) is the leading cause of morbidity and mortality in the industrialized countries. Assessment of symptomatic patients with suspected obstructive CAD is a common reason for a clinical visit. Noninvasive anatomical and functional imaging are established tools to rule-in and rule-out CAD, to assess the severity of disease and to determine the potential risk of future cardiovascular events. In this review, we discuss the updated Guidelines from the European Society of Cardiology on Chronic Coronary Syndromes and explore the different imaging modalities used in current clinical practice for the noninvasive assessment of CAD. The pros and cons of each method, especially comparing anatomical and functional testing, are presented. Furthermore we we address the practical clinical aspects in the selection of the optimal noninvasive tests according to clinical need.

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Advanced Imaging in Musculoskeletal Oncology: Moving Away From RECIST and Embracing Advanced Bone and Soft Tissue Tumor Imaging (ABASTI)—Part II—Novel Functional Imaging Techniques

Seminars in Ultrasound CT and MRI ◽

10.1053/j.sult.2020.08.013 ◽

2020 ◽

Author(s):

Raul Fernando Valenzuela ◽

John E. Madewell ◽

Vikas Kundra ◽

Colleen M. Costelloe

Keyword(s):

Soft Tissue ◽

Functional Imaging ◽

Soft Tissue Tumor ◽

Tumor Imaging ◽

Imaging Techniques ◽

Advanced Imaging ◽

Tissue Tumor ◽

Musculoskeletal Oncology

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PET functional imaging of deep brain stimulation in the healthy rat brain

Klinische Neurophysiologie ◽

10.1055/s-0034-1371301 ◽

2014 ◽

Vol 45 (01) ◽

Author(s):

N Van Den Berge ◽

V Keereman ◽

C Vanhove ◽

P van Mierlo ◽

B Van Nieuwenhuyse ◽

...

Keyword(s):

Deep Brain Stimulation ◽

Rat Brain ◽

Functional Imaging ◽

Brain Stimulation ◽

Deep Brain

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Radiation oncology and functional imaging

Nuklearmedizin ◽

10.1055/s-0038-1625213 ◽

2005 ◽

Vol 44 (S 01) ◽

pp. S38-S40

Author(s):

Th. Herrmann

Keyword(s):

Functional Imaging ◽

Radiation Oncology ◽

Bronchogenic Carcinoma ◽

Brain Tumours ◽

Tumour Volume ◽

Target Volume ◽

Head And Neck Tumours ◽

Pet Ct ◽

Surrounding Healthy Tissue ◽

Prostate Carcinomas

Summary:PET/CT imaging is most likely to be of use in radiation oncology with patients who have poorly defined target volume areas, e.g. brain tumours, bronchogenic carcinoma, and cases of miscellaneous geographical miss. Other tumours that call for dose escalated radiotherapy, such as head and neck tumours, bronchogenic carcinoma, and prostate carcinomas may further benefit from an accurate delineation of the metabolically active tumour volume and its differentiation from surrounding healthy tissue, or tumour atelectasis.

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Effects of Observer Variation on Performance in Probabilistic Diagnosis of Jaundice

Methods of Information in Medicine ◽

10.1055/s-0038-1635304 ◽

1981 ◽

Vol 20 (03) ◽

pp. 163-168 ◽

Cited By ~ 3

Author(s):

G. Llndberg

Keyword(s):

Physical Examination ◽

System Performance ◽

Transition Matrix ◽

Bayes Theorem ◽

Observer Variation ◽

Kappa Statistics ◽

Diagnostic Categories ◽

Number Of Patients ◽

Probability Transition Matrix ◽

Probabilistic Diagnosis

A system for probabilistic diagnosis of jaundice has been used for studying the effects of taking into account the unreliability of diagnostic data caused by observer variation. Fourteen features from history and physical examination were studied. Bayes’ theorem was used for calculating the probabilities of a patient’s belonging to each of four diagnostic categories.The construction sample consisted of 61 patients. An equal number of patients were tested in the evaluation sample. Observer variation on the fourteen features had been assessed in two previous studies. The use of kappa-statistics for measuring observer variation allowed the construction of a probability transition matrix for each feature. Diagnostic probabilities could then be calculated with and without the inclusion of weights for observer variation. Tests of system performance revealed that discriminatory power remained unchanged. However, the predictions rendered by the variation-weighted system were diffident. It is concluded that taking observer variation into account may weaken the sharpness of probabilistic diagnosis but it may also help to explain the value of probabilistic diagnosis in future applications.

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Observer Variation in Clinical Diagnosis - A Computer-Aided Assessment of its Magnitude and Importance in 552 Patients with Abdominal Pain

Methods of Information in Medicine ◽

10.1055/s-0038-1636102 ◽

1973 ◽

Vol 12 (02) ◽

pp. 108-113 ◽

Cited By ~ 20

Author(s):

P. W. Gill ◽

D. J. Leaper ◽

P. J. Guillou ◽

J. R. Staniland ◽

J. C. Horhocks ◽

...

Keyword(s):

Abdominal Pain ◽

Clinical Diagnosis ◽

Error Rate ◽

Diagnostic System ◽

Diagnostic Error ◽

Observer Variation ◽

History Taking ◽

Computer Aided ◽

Computer Based ◽

Initial Survey

This report describes an evaluation of »observer variation« in history taking and examination of patients with abdominal pain. After an initial survey in which the degree of observer variation amongst the present authors fully confirmed previous rather gloomy forecasts, a system of »agreed definitions« was produced, and further studies showed a rapid and considerable fall in the degree of observer variation between the data recorded by the same authors. Finally, experience with a computer-based diagnostic system using the same system of agreed definitions showed the maximum diagnostic error rate due to faulty acquisition of data to be low (4.7°/o in a series of 552 cases). It is suggested as a result of these studies that — at least in respect of abdominal pain — errors in data acquisition by the clinician need not be the prime cause of faulty diagnoses.

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