Enhanced tumor cell selectivity of adriamycin-monoclonal antibody conjugate via a poly(ethylene glycol)-based cleavable linker

2002 ◽  
Vol 79 (1-3) ◽  
pp. 229-242 ◽  
Author(s):  
T Suzawa
2000 ◽  
Vol 11 (2) ◽  
pp. 258-266 ◽  
Author(s):  
Tian-Lu Cheng ◽  
Bing-Mae Chen ◽  
Ji-Wang Chern ◽  
Ming-Fang Wu ◽  
Steve R. Roffler

2010 ◽  
Vol 21 (2) ◽  
pp. 191-198 ◽  
Author(s):  
Yajun Duan ◽  
Cuihong Yang ◽  
Zhenfang Zhang ◽  
Jianfeng Liu ◽  
Junnian Zheng ◽  
...  

2005 ◽  
Vol 16 (5) ◽  
pp. 1225-1231 ◽  
Author(s):  
Tian-Lu Cheng ◽  
Chiu-Min Cheng ◽  
Bing-Mae Chen ◽  
Der-An Tsao ◽  
Kuo-Hsiang Chuang ◽  
...  

2019 ◽  
Vol 3 (2) ◽  
Author(s):  
Fen Lin

 Gelatin as one kind of nano-drug carrier is a polysaccharide which can be absorbed after releasing all nano-drugs. Poly(ethylene glycol) as a polymer material that can modify nano-drugs is able to extend circulatory time of doxorubicin and aspirin, enhance stability and reduce toxicity. At precancerous, aspirin will be released slowly to resist inflammation. When tumor cell appears at a more advance stage, doxorubicin release from Gel to achieve anti-tumor effect. After all those steps, poly (ethylene glycol) could be expelled from body. In brief, the nano-drug that has doxorubicin and aspirin is able to prevent the growth of tumor cells and kill them when they appear more precisely.


2019 ◽  
Vol 10 (10) ◽  
Author(s):  
Anton Bonartsev ◽  
Vera Voinova ◽  
Elizaveta Akoulina ◽  
Andrey Dudun ◽  
Irina Zharkova ◽  
...  

2007 ◽  
Vol 32 (5) ◽  
pp. 431-446 ◽  
Author(s):  
Tahar Bartil ◽  
Mahmoud Bounekhel ◽  
Cedric Calberg ◽  
Robert Jerome

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