3565 Protective effects of carvedilol against doxorubicin-induced apoptosis in cardiac muscle cells

2003 ◽  
Vol 24 (5) ◽  
pp. 693
Author(s):  
S GARIBALDI
Keyword(s):  
Cardiac Muscle ◽  
Muscle Cells ◽  
Protective Effects ◽  
Cardiac Muscle Cells ◽  
Induced Apoptosis

scholarly journals Mdivi-1 attenuates sodium azide-induced apoptosis in H9c2 cardiac muscle cells

2017 ◽  
Vol 16 (5) ◽  
pp. 5972-5978 ◽  
Author(s):  
Xuehua Xu ◽  
Chengliang Luo ◽  
Zhixiang Zhang ◽  
Jun Hu ◽  
Xiangting Gao ◽  
...  
Keyword(s):  
Cardiac Muscle ◽  
Sodium Azide ◽  
Muscle Cells ◽  
Cardiac Muscle Cells ◽  
Induced Apoptosis

Curcumin potentiates doxorubicin-induced apoptosis in H9c2 cardiac muscle cells through generation of reactive oxygen species

2011 ◽  
Vol 44 (13) ◽  
pp. S357
Author(s):  
Gholamreza Karimi ◽  
Javad Behravan ◽  
Fateme Mosaffa ◽  
Leila Hosseinzadeh ◽  
Bahrami Gholamreza
Keyword(s):  
Reactive Oxygen Species ◽  
Cardiac Muscle ◽  
Reactive Oxygen ◽  
Muscle Cells ◽  
Oxygen Species ◽  
Cardiac Muscle Cells ◽  
Induced Apoptosis

scholarly journals Human Relaxin-2 (Serelaxin) Attenuates Oxidative Stress in Cardiac Muscle Cells Exposed In Vitro to Hypoxia–Reoxygenation. Evidence for the Involvement of Reduced Glutathione Up-Regulation

Antioxidants ◽  
2020 ◽  
Vol 9 (9) ◽  
pp. 774
Author(s):  
Silvia Nistri ◽  
Claudia Fiorillo ◽  
Matteo Becatti ◽  
Daniele Bani
Keyword(s):  
Oxidative Stress ◽  
Cardiac Muscle ◽  
Reduced Glutathione ◽  
Cell Damage ◽  
Antioxidant Properties ◽  
Muscle Cells ◽  
Protective Effects ◽  
Cardiac Muscle Cells ◽  
Relaxin 2

Serelaxin (RLX) designates the pharmaceutical form of the human natural hormone relaxin-2 that has been shown to markedly reduce tissue and cell damage induced by hypoxia and reoxygenation (HR). The evidence that RLX exerts similar protective effects on different organs and cells at relatively low, nanomolar concentrations suggests that it specifically targets a common pathogenic mechanism of HR-induced damage, namely oxidative stress. In this study we offer experimental evidence that RLX (17 nmol L-1), added to the medium of HR-exposed H9c2 rat cardiac muscle cells, significantly reduces cell oxidative damage, mitochondrial dysfunction and apoptosis. These effects appear to rely on the up-regulation of the cellular availability of reduced glutathione (GSH), a ubiquitous endogenous antioxidant metabolite. Conversely, superoxide dismutase activity was not influenced by RLX, which, however, was not endowed with chemical antioxidant properties. Taken together, these findings verify the major pharmacological role of RLX in the protection against HR-induced oxidative stress, and shed first light on its mechanisms of action.

Curcumin potentiates doxorubicin-induced apoptosis in H9c2 cardiac muscle cells through generation of reactive oxygen species

2011 ◽  
Vol 49 (5) ◽  
pp. 1102-1109 ◽  
Author(s):  
Leila Hosseinzadeh ◽  
Javad Behravan ◽  
Fatemeh Mosaffa ◽  
Gholamreza Bahrami ◽  
Ahmadreza Bahrami ◽  
...  
Keyword(s):  
Reactive Oxygen Species ◽  
Cardiac Muscle ◽  
Reactive Oxygen ◽  
Muscle Cells ◽  
Oxygen Species ◽  
Cardiac Muscle Cells ◽  
Induced Apoptosis

Plantainoside D protects adriamycin-induced apoptosis in H9c2 cardiac muscle cells via the inhibition of ROS generation and NF-κB activation

Life Sciences ◽  
2007 ◽  
Vol 80 (4) ◽  
pp. 314-323 ◽  
Author(s):  
Do-Sung Kim ◽  
Eun-Rhan Woo ◽  
Soo-Wan Chae ◽  
Ki-Chan Ha ◽  
Geum-Hwa Lee ◽  
...  
Keyword(s):  
Cardiac Muscle ◽  
Muscle Cells ◽  
Ros Generation ◽  
Cardiac Muscle Cells ◽  
Induced Apoptosis
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