100-g Glucose Test Finds More Gestational Diabetes

2007 ◽  
Vol 37 (15) ◽  
pp. 16
Author(s):  
MITCHEL L. ZOLER
Keyword(s):  
Gestational Diabetes ◽  
Glucose Test

scholarly journals Incretin Effect in Women with Former Gestational Diabetes within a Short Period after Delivery

2012 ◽  
Vol 2012 ◽  
pp. 1-4 ◽  
Author(s):  
G. Pacini ◽  
A. Tura ◽  
Y. Winhofer ◽  
A. Kautzky-Willer
Keyword(s):  
Gestational Diabetes ◽  
Beta Cell ◽  
Cell Function ◽  
Normal Pregnancy ◽  
Incretin Effect ◽  
Cell Dysfunction ◽  
Short Period ◽  
Glucose Test

Background and Aims. Women with former gestational diabetes (fGDM) are characterized by impaired beta-cell function (BC). Incretin hormones contribute to insulin secretion after oral administration of glucose. We aimed to assess the possible role of incretins on altered insulin release in fGDM.Materials and Methods. We studied 104 fGDM women within 6 months after delivery and 35 healthy women after normal pregnancy (CNT) with a 75 g oral (OGTT) and a 0.33 g/kg intravenous (IVGTT) glucose test, both lasting 3 h. The ratio of suprabasal areas under the concentration curves for glucose (dAUCGL) and C-peptide (dAUCCP) evaluated BC during OGTT (BCOG) and IVGTT (BCIV). Incretin effect was computed in all fGDM and in fGDM with normal tolerance (fGDMNGT) and with impaired glucose regulation (fGDMIGR).Results.dAUCGLof fGDM was higher (P<0.0001) than CNT for both tests; whiledAUCCPwere not different.BCOGandBCIVwere lower in fGDM versus CNT (1.42±0.17nmolCP/mmolGLUCversus2.53±0.61,P=0.015and0.41±0.03versus0.68±0.10,P=0.0006, respectively). IE in CNT (66±4 %) was not different from that of all fGDM (59±3) andfGDMNGT(60±3), but higher than that offGDMIGR(52±6;P=0.03). IE normalized to BMI was2.77±0.19 % m2/kg in CNT, higher than that offGDMIGR(1.75±0.21;P=0.02) and also offGDMNGT  (2.33±0.11;P=0.038).Conclusion. Compromised IE characterizesfGDMIGR. In both fGDM categories, regardless their glucose tolerance, IE normalized to BMI was reduced, signifying an intrinsic characteristic of fGDM. Therefore, the diminished IE of fGDM seems to reflect an early abnormality of the general beta-cell dysfunction in the progression toward type 2 diabetes.

scholarly journals Accuracy of the random glucose test as screening test for gestational diabetes mellitus: a systematic review

2011 ◽  
Vol 154 (2) ◽  
pp. 130-135 ◽  
Author(s):  
Marsha van Leeuwen ◽  
Brent C. Opmeer ◽  
Yildirim Yilmaz ◽  
Jacqueline Limpens ◽  
Mireille J. Serlie ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Systematic Review ◽  
Gestational Diabetes ◽  
Gestational Diabetes Mellitus ◽  
Screening Test ◽  
Glucose Test

Fasting Plasma Glucose Test at the First Prenatal Visit as a Screen for Gestational Diabetes

2003 ◽  
Vol 101 (6) ◽  
pp. 1197-1203 ◽  
Author(s):  
David A. Sacks ◽  
Wansu Chen ◽  
Girma Wolde-Tsadik ◽  
Thomas A. Buchanan
Keyword(s):  
Gestational Diabetes ◽  
Plasma Glucose ◽  
Fasting Plasma Glucose ◽  
Prenatal Visit ◽  
Fasting Plasma ◽  
Glucose Test

scholarly journals Predictors of Treatment Requirements in Women with Gestational Diabetes: A Retrospective Analysis

2021 ◽  
Vol 10 (19) ◽  
pp. 4421
Author(s):  
Friederike Weschenfelder ◽  
Karolin Lohse ◽  
Thomas Lehmann ◽  
Ekkehard Schleußner ◽  
Tanja Groten
Keyword(s):  
Risk Factors ◽  
Gestational Diabetes ◽  
Insulin Treatment ◽  
Treatment Options ◽  
Patient Characteristics ◽  
Multivariate Regression Analysis ◽  
Fetal Ultrasound ◽  
Potential Risk Factors ◽  
Glucose Test ◽  
Bolus Insulin

The diagnosis of gestational diabetes is usually very stressful for pregnant women, especially because they fear that insulin treatment may become necessary. Knowledge about personal risk factors predicting the probability of insulin treatment could therefore help to improve acceptance of the diagnosis and therapy adherence. The aim of this study was to find potential risk factors for insulin dependency and treatment requirements using information available at the time of diagnosis of gestational diabetes during pregnancy. We included 454 singleton pregnancies diagnosed ≥24 weeks of gestation. Multivariate regression analysis was used to evaluate independent associations of metabolic, anthropometric and fetal ultrasound parameters with the general need for insulin treatment and further stratified treatment options: diet (n = 275), bolus insulin only (n = 45), basal insulin only (n = 73) and multiple daily injections (n = 61). Receiver operator characteristics and cut-off values for independent variables were generated. Treatment groups differed significantly concerning pre-pregnancy weight and BMI as well as fasting glucose and 1 h glucose test values. Significant cut-offs for insulin dependency were HbA1c level of 5.4%, FPG of 5.5 mmol/L and 1 h glucose of 10.6 mmol/L. At time of diagnosis, certain patient characteristics and measurements can help to predict treatment necessities and therefore improve individualized counselling.

Diagnostics and laboratory monitoring of gestational diabetes mellitus in Russia. The authors' view of the problem and controversial issues

2014 ◽  
Vol 63 (4) ◽  
pp. 98-103
Author(s):  
Vladimir Vladimirovich Dorofeykov ◽  
Natalia Evgenyevna Androsova
Keyword(s):  
Diabetes Mellitus ◽  
Gestational Diabetes ◽  
Gestational Diabetes Mellitus ◽  
Glycosylated Hemoglobin ◽  
Venous Blood ◽  
Tolerance Test ◽  
Oral Glucose ◽  
Laboratory Services ◽  
Blood Glucose Test ◽  
Glucose Test

Despite the existence of the Russian Consensus on gestational diabetes mellitus (GDM) since 2012 in the Russian Federation, its implementation into clinical practice has been slow, partially because its creation took place without the participation of laboratory services. In this review issues of preanalytical and analytical considerations of such laboratory tests as the blood glucose test, oral glucose tolerance test (OGTT), glycosylated hemoglobin test are discussed. If the presence of prandial hyperglycemia from 5.1 to 5.6 mmol/l is identified, testing should be repeated to confirm the diagnosis of GDM. OGTT must be performed using venous blood samples with fluoride in a specialized laboratory with fast transportation of samples.

scholarly journals Role of O'sullivan's Test in Screening of Pregnant Women for Gestational Diabetes in Rural Area

2011 ◽  
Vol 3 (2) ◽  
pp. 86-88 ◽  
Author(s):  
Neema Acharya ◽  
Anil Inamdar
Keyword(s):  
Gestational Diabetes ◽  
Pregnant Women ◽  
Rural Area ◽  
Cost Effective ◽  
Perinatal Morbidity ◽  
Diabetes In Pregnancy ◽  
High Risk Factors ◽  
Cost Effective Method ◽  
Glucose Test

ABSTRACT Objective To study the role of O'sullivan's test in screening of pregnant women for gestational diabetes in rural area. Materials and methods A total of 1000 antenatal patients were screened for gestational diabetes with 50 gm glucose test (O'sullivan's test), 1-hour plasma glucose value more than 130 gm/dl was considered screen positive who were subjected to 3-hour GTT. Results The incidence of gestational diabetes in our study was 0.5%, the maternal and fetal high-risk factors in these patients were PROM, hydromnios and birth weight more than 3.5 kg. Conclusion O'sullivan's test is a cost-effective method of screening of diabetes in pregnancy which is associated with increased maternal and perinatal morbidity.

scholarly journals Implementing a Reminder System in the Northern Part of Belgium to Stimulate Postpartum Screening for Glucose Intolerance in Women with Gestational Diabetes: The “Sweet Pregnancy” Project

2017 ◽  
Vol 2017 ◽  
pp. 1-9 ◽  
Author(s):  
Katrien Benhalima ◽  
Sabine Verstraete ◽  
Frederik Muylle ◽  
Katelijn Decochez ◽  
Roland Devlieger ◽  
...  
Keyword(s):  
Primary Care ◽  
Gestational Diabetes ◽  
Plasma Glucose ◽  
First Year ◽  
Impaired Fasting Glycaemia ◽  
Reminder System ◽  
Postpartum Screening ◽  
Glucose Test ◽  
Fasting Glycaemia

Aims. To evaluate the feasibility and efficacy of a gestational diabetes (GDM) recall register on the long-term screening uptake postpartum and to evaluate the prevalence of prediabetes postpartum. Methods. Evaluation of a GDM recall register implemented in 66 obstetrical centers in the northern part of Belgium from 2009 to 2016. Registrants receive yearly reminders to have a fasting plasma glucose test in primary care to timely detect prediabetes. Results. After 6 years, 7269 women were registered. The yearly response rates varied from 74.4% after the first year to 61.8% after the fifth year. The number of women who reported a screening test varied from 67.4% after the first year to 71.9% after the fifth year. Compared to women who responded at least once to a reminder, women who never responded were more often <30 years (41.4% versus 33.9%, p<0.001) and were more often obese (29.3% versus 20.8%, p≤0.001). Over a period of 6 years, 7.3% (CI 6.0%–8.8%) developed diabetes and 27.4% (CI 23.9%–31.0%) developed impaired fasting glycaemia. Conclusion. We show now the long-term feasibility and efficacy of a GDM recall register to stimulate screening postpartum. One-third of women developed prediabetes within 6 years.

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