Experiments on the transmission of Babesia major and Babesia bigemina by Haemaphysalis punctata

1996 ◽  
Vol 67 (1-2) ◽  
pp. 89-98 ◽  
Author(s):  
Hong Yin ◽  
Wenshun Lu ◽  
Jianxun Luo ◽  
Qicai Zhang ◽  
Wenxiang Lu ◽  
...  
Keyword(s):  
Babesia Bigemina ◽  
Haemaphysalis Punctata

On the Structure of the Spiracles of a Tick—Haemaphysalis punctata, Canesteini and Fanzago

Parasitology ◽  
1908 ◽  
Vol 1 (4) ◽  
pp. 347-351 ◽  
Author(s):  
G. H. F. Nuttall ◽  
W. F. Cooper ◽  
L. E. Robinson
Keyword(s):  
Ixodes Ricinus ◽  
Detailed Structure ◽  
Short Account ◽  
Haemaphysalis Punctata ◽  
The Subject ◽  
Single Figure

The detailed structure of the spiracles in the Ixodoidea has hitherto received little or no attention at the hands of zoologists; at the same time, these organs are sufficiently extraordinary to make it a matter of surprise that, so far as our knowledge of the literature goes, not one of the numerous contributors to the subject of tick anatomy has found it worth while to undertake a complete description or to publish figures to illustrate it. Batelli (1891) gives a short account of the structure of the spiracle of a tick, presumably Ixodes ricinus, with a single figure, but with this exception we have been unable to find any further information on the subject.

scholarly journals A Comparative Genomic Study of Attenuated and Virulent Strains of Babesia bigemina

Pathogens ◽  
2021 ◽  
Vol 10 (3) ◽  
pp. 318
Author(s):  
Bernardo Sachman-Ruiz ◽  
Luis Lozano ◽  
José J. Lira ◽  
Grecia Martínez ◽  
Carmen Rojas ◽  
...  
Keyword(s):  
In Vitro Culture ◽  
Virulence Genes ◽  
Laboratory Strain ◽  
Host Cells ◽  
Comparative Genomic ◽  
Local Alignment ◽  
Host Immune System ◽  
Babesia Bigemina ◽  
Genomic Study

Cattle babesiosis is a socio-economically important tick-borne disease caused by Apicomplexa protozoa of the genus Babesia that are obligate intraerythrocytic parasites. The pathogenicity of Babesia parasites for cattle is determined by the interaction with the host immune system and the presence of the parasite’s virulence genes. A Babesia bigemina strain that has been maintained under a microaerophilic stationary phase in in vitro culture conditions for several years in the laboratory lost virulence for the bovine host and the capacity for being transmitted by the tick vector. In this study, we compared the virulome of the in vitro culture attenuated Babesia bigemina strain (S) and the virulent tick transmitted parental Mexican B. bigemina strain (M). Preliminary results obtained by using the Basic Local Alignment Search Tool (BLAST) showed that out of 27 virulence genes described and analyzed in the B. bigemina virulent tick transmitted strain, only five were fully identified in the attenuated laboratory strain. In all cases, the identity and coverture of the identified genes of the wildtype strain were higher than those of the laboratory strain. This finding is putatively associated with the continuous partial loss of virulence genes in the laboratory strain after several passages of the parasite population under optimal in vitro growth conditions. The loss of virulence factors might be reflected in the absence of symptoms of the disease in cattle inoculated with the attenuated strain despite the presence of infection in the bovine host cells.

scholarly journals Applying Machine Learning to Predict the Exportome of Bovine and Canine Babesia Species That Cause Babesiosis

Pathogens ◽  
2021 ◽  
Vol 10 (6) ◽  
pp. 660
Author(s):  
Stephen J. Goodswen ◽  
Paul J. Kennedy ◽  
John T. Ellis
Keyword(s):  
Machine Learning ◽  
Severe Disease ◽  
Economic Loss ◽  
Babesia Bovis ◽  
Training Data ◽  
Babesia Bigemina ◽  
Bovine Babesiosis ◽  
Canine Babesiosis ◽  
Clinically Significant ◽  
Significant Disease

Babesia infection of red blood cells can cause a severe disease called babesiosis in susceptible hosts. Bovine babesiosis causes global economic loss to the beef and dairy cattle industries, and canine babesiosis is considered a clinically significant disease. Potential therapeutic targets against bovine and canine babesiosis include members of the exportome, i.e., those proteins exported from the parasite into the host red blood cell. We developed three machine learning-derived methods (two novel and one adapted) to predict for every known Babesia bovis, Babesia bigemina, and Babesia canis protein the probability of being an exportome member. Two well-studied apicomplexan-related species, Plasmodium falciparum and Toxoplasma gondii, with extensive experimental evidence on their exportome or excreted/secreted proteins were used as important benchmarks for the three methods. Based on 10-fold cross validation and multiple train–validation–test splits of training data, we expect that over 90% of the predicted probabilities accurately provide a secretory or non-secretory indicator. Only laboratory testing can verify that predicted high exportome membership probabilities are creditable exportome indicators. However, the presented methods at least provide those proteins most worthy of laboratory validation and will ultimately save time and money.

scholarly journals Stable transformation of Babesia bigemina and Babesia bovis using a single transfection plasmid

2018 ◽  
Vol 8 (1) ◽  
Author(s):  
Marta G. Silva ◽  
Donald P. Knowles ◽  
Monica L. Mazuz ◽  
Brian M. Cooke ◽  
Carlos E. Suarez
Keyword(s):  
Stable Transformation ◽  
Babesia Bovis ◽  
Babesia Bigemina

Serological responses to Babesia bovis vaccination in cattle previously infected with Babesia bigemina

2010 ◽  
Vol 170 (1-2) ◽  
pp. 30-36 ◽  
Author(s):  
M.P. Combrink ◽  
P.C. Troskie ◽  
F. Du Plessis ◽  
A.A. Latif
Keyword(s):  
Babesia Bovis ◽  
Babesia Bigemina

The Life History of Babesia bigemina in the North American Fever Tick

Science ◽  
1931 ◽  
Vol 73 (1901) ◽  
pp. 620-621
Author(s):  
Emery Westervelt Dennis
Keyword(s):  
Life History ◽  
North American ◽  
Babesia Bigemina ◽  
The North ◽  
History Of

scholarly journals Tristeza parasitária bovina no Sertão da Paraíba

2011 ◽  
Vol 31 (3) ◽  
pp. 239-243 ◽  
Author(s):  
V.M.M. Costa ◽  
A.L. Rodrigues ◽  
J.M.A. Medeiros ◽  
M.B. Labruna ◽  
S.V.D. Simões ◽  
...  
Keyword(s):  
Babesia Bigemina

Descrevem-se 24 surtos de tristeza parasitária bovina no sertão paraibano, sendo 18 de anaplasmose por Anaplasma margimale, dois de babesiose por Babesia bigemina, dois por Babesia não identificada e dois por infecção mista de A. marginale e Babesia sp. Os surtos ocorreram entre agosto de 2007 a outubro de 2009, porém, com uma concentração dos surtos no final do período chuvoso e início do período seco de cada ano, sendo 22 em animais adultos e dois em bezerros de aproximadamente 11 meses. Dois surtos ocorreram em bovinos da raça Nelore, um em animais da raça Gir e os 21 restantes ocorreram em animais das raças Holandês, Pardo Suiço e mestiços das mesmas com zebuínos. Conclui-se que no sertão da Paraíba há áreas de instabilidade enzoótica, ocorrendo surtos de tristeza no final da época de chuvas, principalmente nas áreas de planaltos e serras da região da Borborema e em áreas úmidas como a Bacia do Rio do Peixe, Rio Piranhas e Rio Espinharas em que há a formação de microclimas favoráveis à sobrevivência do carrapato.

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