228 Cytotoxicity, inhibition of protein synthesis and induction of stress protein expression in HEP G2 cell line in response to zearalenone

2003 ◽  
Vol 144 ◽  
pp. s64-s65 ◽  
Author(s):  
Wafa Hassen ◽  
Isabelle Baudrimont ◽  
M. Moncef Ladjimi ◽  
Edmond Creppy ◽  
Hassen Bacha
Keyword(s):  
Protein Synthesis ◽  
Protein Expression ◽  
Cell Line ◽  
Stress Protein ◽  
Hep G2 ◽  
Inhibition Of Protein Synthesis

scholarly journals Pattern of stress protein expression in human lung cell-line A549 after short- or long-term exposure to cadmium.

2000 ◽  
Vol 108 (1) ◽  
pp. 55-60 ◽  
Author(s):  
F Croute ◽  
B Beau ◽  
C Arrabit ◽  
Y Gaubin ◽  
F Delmas ◽  
...  
Keyword(s):  
Protein Expression ◽  
Cell Line ◽  
Human Lung ◽  
Stress Protein ◽  
Human Lung Cell Line ◽  
Lung Cell Line

SYNTHESIS AND CYTOTOXICITY OF POLYHYDROXYLATED CHOLESTEROL DERIVATIVES

2018 ◽  
Vol 56 (4) ◽  
pp. 467
Author(s):  
Thu Thuy Thi Tran ◽  
Ha Thi Dinh ◽  
Phương Lan Doan ◽  
Long Quoc Pham ◽  
Quang Dai Ngo
Keyword(s):  
Hepatocellular Carcinoma ◽  
Cell Line ◽  
Cell Lines ◽  
Carcinoma Cell ◽  
Addition Compound ◽  
Hep G2 ◽  
Physical Methods ◽  
Hepatocellular Carcinoma Cell Line ◽  
Human Hepatocellular Carcinoma Cell ◽  
Hepatocellular Carcinoma Cell

Eight polyhydroxylated cholesterol derivatives (1-8) were prepared from cholesterol, using oxidative reagents as SeO2, OsO4/NMO, HCOOH/H2O2 and BH3/ H2O2. Their structures were elucidated by using physical methods including NMR 1D and 2D. These compounds were evaluated against two cancer cell lines (Hep-G2, T98). Compounds 2, 4 and 8 inhibits human hepatocellular carcinoma cell line (Hep-G2) with IC50 4.69, 4.98 and 2.89 µg/mL, respectively. In addition, compound 8 exhibited strong cytotoxicity against T98 cell line (glioblastoma) with IC50 = 2.28 μM.

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