Control of medicine release from solid dispersion through poly(ethylene oxide)-carboxyvinylpolymer interaction1This article is Part X of ‘Application of the Solid Dispersion Method to the Controlled Release of Medicine’. Part IX: Ozeki, T., Yuasa, H., Kanaya, Y., 1997. Int. J. Pharmaceut., 155, 209–217.1

1998 ◽  
Vol 165 (2) ◽  
pp. 239-244 ◽  
Author(s):  
Tetsuya Ozeki ◽  
Hiroshi Yuasa ◽  
Yoshio Kanaya
Keyword(s):  
Controlled Release ◽  
Ethylene Oxide ◽  
Solid Dispersion ◽  
Dispersion Method ◽  
Poly Ethylene Oxide ◽  
Poly Ethylene

Solid dispersion of acetaminophen and poly(ethylene oxide) prepared by hot-melt mixing

2010 ◽  
Vol 395 (1-2) ◽  
pp. 53-61 ◽  
Author(s):  
Min Yang ◽  
Peng Wang ◽  
Chien-Yueh Huang ◽  
M. Sherry Ku ◽  
Huiju Liu ◽  
...  
Keyword(s):  
Ethylene Oxide ◽  
Solid Dispersion ◽  
Melt Mixing ◽  
Poly Ethylene Oxide ◽  
Poly Ethylene ◽  
Hot Melt

scholarly journals Degradable Poly(ethylene oxide)-Like Plasma Polymer Films Used for the Controlled Release of Nisin

Polymers ◽  
2020 ◽  
Vol 12 (6) ◽  
pp. 1263 ◽  
Author(s):  
Jaroslav Kousal ◽  
Jana Sedlaříková ◽  
Zuzana Kolářová-Rašková ◽  
Zdeněk Krtouš ◽  
Liliana Kučerová ◽  
...  
Keyword(s):  
Controlled Release ◽  
Ethylene Oxide ◽  
Biologically Active ◽  
Process Conditions ◽  
Plasma Power ◽  
Permeability Study ◽  
Poly Ethylene Oxide ◽  
Poly Ethylene ◽  
Atr Spectroscopy ◽  
Permeation Properties

Poly(ethylene oxide) (PEO)-like thin films were successfully prepared by plasma-assisted vapor thermal deposition (PAVTD). PEO powders with a molar weight (Mw) between 1500 g/mol and 600,000 g/mol were used as bulk precursors. The effect of Mw on the structural and surface properties was analyzed for PEO films prepared at a lower plasma power. Fourier transform (FTIR-ATR) spectroscopy showed that the molecular structure was well preserved regardless of the Mw of the precursors. The stronger impact of the process conditions (the presence/absence of plasma) was proved. Molecular weight polydispersity, as well as wettability, increased in the samples prepared at 5 W. The influence of deposition plasma power (0–30 W) on solubility and permeation properties was evaluated for a bulk precursor of Mw 1500 g/mol. The rate of thickness loss after immersion in water was found to be tunable in this way, with the films prepared at the highest plasma power showing higher stability. The effect of plasma power deposition conditions was also shown during the permeability study. Prepared PEO films were used as a cover, and permeation layers for biologically active nisin molecule and a controlled release of this bacteriocin into water was achieved.

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