Regeneration after tall hair cell damage following severe acoustic trauma in adult pigeons: correlation between cochlear morphology, compound action potential responses and single fiber properties in single animals

1996 ◽  
Vol 102 (1-2) ◽  
pp. 133-154 ◽  
Author(s):  
Marcus Müller ◽  
Jean W.T. Smolders ◽  
Danping Ding-Pfennigdorff ◽  
Rainer Klinke
Keyword(s):  
Action Potential ◽  
Hair Cell ◽  
Cell Damage ◽  
Compound Action Potential ◽  
Acoustic Trauma ◽  
Single Fiber ◽  
Fiber Properties ◽  
Hair Cell Damage ◽  
Cochlear Morphology ◽  
Compound Action

Hair cell damage produced by acoustic trauma in the chick cochlea

1987 ◽  
Vol 25 (2-3) ◽  
pp. 267-286 ◽  
Author(s):  
Douglas A. Cotanche ◽  
James C. Saunders ◽  
Lewis G. Tilney
Keyword(s):  
Hair Cell ◽  
Cell Damage ◽  
Acoustic Trauma ◽  
Hair Cell Damage

Histological evaluation of cochlear hair cell damage from noise-induced hearing loss in chinchillas

1990 ◽  
Vol 48 (3) ◽  
pp. 332-333
Author(s):  
R.V. Harrison ◽  
R.J. Mount ◽  
P. White ◽  
N. Fukushima
Keyword(s):  
Hair Cell ◽  
Evoked Potential ◽  
Cell Damage ◽  
Acoustic Trauma ◽  
Histological Evaluation ◽  
Cell Integrity ◽  
Functional Changes ◽  
Cochlear Hair Cell ◽  
Left And Right ◽  
Contralateral Ear

In studies which attempt to define the influence of various factors on recovery of hair cell integrity after acoustic trauma, an experimental and a control ear which initially have equal degrees of damage are required. With in a group of animals receiving an identical level of acoustic trauma there is more symmetry between the ears of each individual, in respect to function, than between animals. Figure 1 illustrates this, left and right cochlear evoked potential (CAP) audiograms are shown for two chinchillas receiving identical trauma. For this reason the contralateral ear is used as control.To compliment such functional evaluations we have devised a scoring system, based on the condition of hair cell stereocilia as revealed by scanning electron microscopy, which permits total stereociliar damage to be expressed numerically. This quantification permits correlation of the degree of structural pathology with functional changes. In this paper wereport experiments to verify the symmetry of stereociliar integrity between two ears, both for normal (non-exposed) animals and chinchillas in which each ear has received identical noise trauma.

Hair Cell Damage in the Inner Ear of the Guinea Pig Due to Noise in a Workshop

1987 ◽  
Vol 103 (5) ◽  
pp. 204-211 ◽  
Author(s):  
B. Erlandsson ◽  
H. Hakanson ◽  
A. Ivarsson ◽  
P. Nilsson ◽  
J. Wersall
Keyword(s):  
Guinea Pig ◽  
Hair Cell ◽  
Inner Ear ◽  
Cell Damage ◽  
Hair Cell Damage

XIAP inhibits gentamicin-induced hair cell damage and ototoxicity through the caspase-3/9 pathway

2021 ◽  
pp. 114513
Author(s):  
Dekun Gao ◽  
Hui Wu ◽  
Huiqun Jie ◽  
Min Liang ◽  
Dongzhen Yu ◽  
...  
Keyword(s):  
Hair Cell ◽  
Caspase 3 ◽  
Cell Damage ◽  
Hair Cell Damage
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