PS-106-An international, randomized, placebo-controlled phase 2 trial demonstrates novel effects of DGAT2 antisense inhibition in reducing steatosis without causing hypertriglyceridemia in T2DM patients

Rohit Loomba; Erin Morgan; Maple Fung; Lynnetta Watts; Richard Geary; Sanjay Bhanot

doi:10.1016/s0618-8278(19)30118-5

PS-106-An international, randomized, placebo-controlled phase 2 trial demonstrates novel effects of DGAT2 antisense inhibition in reducing steatosis without causing hypertriglyceridemia in T2DM patients

Journal of Hepatology ◽

10.1016/s0618-8278(19)30118-5 ◽

2019 ◽

Vol 70 (1) ◽

pp. e67-e68 ◽

Cited By ~ 2

Author(s):

Rohit Loomba ◽

Erin Morgan ◽

Maple Fung ◽

Lynnetta Watts ◽

Richard Geary ◽

...

Keyword(s):

Antisense Inhibition ◽

Phase 2 ◽

Phase 2 Trial

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Novel antisense inhibition of diacylglycerol O-acyltransferase 2 for treatment of non-alcoholic fatty liver disease: a multicentre, double-blind, randomised, placebo-controlled phase 2 trial

The Lancet Gastroenterology & Hepatology ◽

10.1016/s2468-1253(20)30186-2 ◽

2020 ◽

Vol 5 (9) ◽

pp. 829-838 ◽

Cited By ~ 4

Author(s):

Rohit Loomba ◽

Erin Morgan ◽

Lynnetta Watts ◽

Shuting Xia ◽

Lisa A Hannan ◽

...

Keyword(s):

Liver Disease ◽

Fatty Liver ◽

Fatty Liver Disease ◽

Antisense Inhibition ◽

Phase 2 ◽

Double Blind ◽

Alcoholic Fatty Liver ◽

Phase 2 Trial ◽

Alcoholic Fatty Liver Disease

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12-Month Follow-up From Phase 2 Trial of Liposomal Amikacin for Inhalation (LAI) in Patients With Nontuberculous Mycobacterial (NTM) Lung Infection

Pneumologie ◽

10.1055/s-0036-1592232 ◽

2016 ◽

Vol 70 (10) ◽

Author(s):

K Olivier ◽

D Griffith ◽

K Winthrop ◽

B Brown-Elliott ◽

G Eagle ◽

...

Keyword(s):

Lung Infection ◽

Phase 2 ◽

Phase 2 Trial

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Resmetirom (MGL-3196) for the treatment of non-alcoholic steatohepatitis: a multicentre, randomised, double-blind, placebo-controlled, phase 2 trial

Yearbook of Paediatric Endocrinology ◽

10.1530/ey.17.14.9 ◽

2020 ◽

Author(s):

Harrison SA ◽

Bashir MR ◽

Guy CD ◽

Zhou R ◽

Moylan CA ◽

...

Keyword(s):

Phase 2 ◽

Double Blind ◽

Double Blind Placebo ◽

Alcoholic Steatohepatitis ◽

Phase 2 Trial

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NGM282 for treatment of non-alcoholic steatohepatitis: a multicentre, randomised, double-blind, placebo-controlled, phase 2 trial

Yearbook of Paediatric Endocrinology ◽

10.1530/ey.15.15.7 ◽

2018 ◽

Author(s):

Harrison SA ◽

Rinella ME ◽

Abdelmalek MF ◽

Trotter JF ◽

Paredes AH ◽

...

Keyword(s):

Phase 2 ◽

Double Blind ◽

Double Blind Placebo ◽

Alcoholic Steatohepatitis ◽

Phase 2 Trial

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Phase 2 Trial of Neoadjuvant Weekly Carboplatin Plus Paclitaxel in Triple Negative Breast Cancer

Case Medical Research ◽

10.31525/ct1-nct04083963 ◽

2019 ◽

Author(s):

Keyword(s):

Breast Cancer ◽

Triple Negative Breast Cancer ◽

Triple Negative ◽

Phase 2 ◽

Phase 2 Trial

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A Phase 2 Trial of OPC-64005 for Major Depressive Disorder

Case Medical Research ◽

10.31525/ct1-nct04244253 ◽

2020 ◽

Author(s):

Keyword(s):

Major Depressive Disorder ◽

Depressive Disorder ◽

Phase 2 ◽

Major Depressive ◽

Phase 2 Trial

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A Phase 2 Trial of SCO-101 in Combination With FOLFIRI for Patients With Metastatic Colorectal Cancer (mCRC) With Acquired Resistance to FOLFIRI

Case Medical Research ◽

10.31525/ct1-nct04247256 ◽

2020 ◽

Author(s):

Keyword(s):

Colorectal Cancer ◽

Metastatic Colorectal Cancer ◽

Acquired Resistance ◽

Phase 2 ◽

Phase 2 Trial

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Faculty Opinions recommendation of Attenuated immunochemotherapy regimen (R-miniCHOP) in elderly patients older than 80 years with diffuse large B-cell lymphoma: a multicentre, single-arm, phase 2 trial.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.10103963.10867063 ◽

2011 ◽

Author(s):

Lazzaro M Repetto

Keyword(s):

Elderly Patients ◽

B Cell ◽

Cell Lymphoma ◽

B Cell Lymphoma ◽

Phase 2 ◽

Phase 2 Trial ◽

Large B Cell Lymphoma ◽

Large B Cell

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Faculty Opinions recommendation of High-dose cytarabine plus high-dose methotrexate versus high-dose methotrexate alone in patients with primary CNS lymphoma: a randomised phase 2 trial.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1382969.855068 ◽

2010 ◽

Author(s):

Tali Siegal

Keyword(s):

Primary Cns Lymphoma ◽

Cns Lymphoma ◽

High Dose ◽

High Dose Methotrexate ◽

Phase 2 ◽

Phase 2 Trial ◽

Dose Methotrexate ◽

High Dose Cytarabine

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Faculty Opinions recommendation of Ipilimumab and fotemustine in patients with advanced melanoma (NIBIT-M1): an open-label, single-arm phase 2 trial.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.717954976.793462183 ◽

2012 ◽

Author(s):

Mark Faries

Keyword(s):

Advanced Melanoma ◽

Phase 2 ◽

Open Label ◽

Phase 2 Trial

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