LEFT VENTRICULAR GLOBAL LONGITUDINAL STRAIN AND LONG-TERM PROGNOSIS IN PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE AFTER ACUTE MYOCARDIAL INFARCTION

2018 ◽  
Vol 71 (11) ◽  
pp. A1712
Author(s):  
Laurien Goedemans ◽  
Rachid Abou ◽  
Georgette Hoogslag ◽  
Nina Marsan ◽  
Victoria Delgado ◽  
...  

scholarly journals P1270Effects of blood pressure variability on layer-specific longitudinal strain in hypertensionP1271 Left atrial dynamics and diastolic function in hypertensive patientsP1272Echocardiographic evaluation of right ventricular function in patients with chronic obstructive pulmonary disease in comparison with healthy groupP1273The impact of preeclampsia on myocardial recovery in women with peripartum cardiomyopahty - speckle tracking studyP1274Diagnostic accuracy of bedside lung ultrasonography in emergency (BLUE) protocol in discriminating cardiovascular causes of acute dyspneaP1275Heart failure with preserved and reduced ejection fraction - the mysterious role of ghrelin in the improvement of cardiac mechanicsP1276Prolonged atrial electromechanical coupling interval in patients with vitamin d deficiencyP1277Early detection of cardiotoxicity induced by new target therapy by strain echocardiography and arterial stiffnessP1278Long term course of bicuspid aortic valve in patients with and without associated cardiac malformations. A single-centre, retrospective cohort studyP1279Left ventricular mechanics in ALCAPA patients post successful repair: really normal?P1280Next generation stress echo computerized software (SECS)P1281Non invasive hemodynamic profile of patients developing inducible ischemia at dobutamine stress echocardiography: a global longitudinal strain investigation P1282Silent myocardial ischaemia is highly prevalent in patients with chronic obstructive pulmonary disease referred for dobutamine stress echocardiographyP1283Silent chronic obstructive pulmonary disease is highly prevalent in patients referred for dobutamine stress echocardiography with shortness of breathP1284Exercise echocardiography for the prediction of mortality after coronary artery by-pass surgery.P1285Exercise echocardiography reveals higher LV myocardial performance efficiency in adolescent elite athletes compared to non-athlete controlsP1287Impact of subclinical left ventricular myocardial dysfunction on exercise capacity in young patients with type 1 diabetes mellitusP1288Mitral annular plane systolic excursion as additional evaluation for left ventricular ejection fractionP12892 dimensional global longitudinal strain and mitral annular plane systolic?excursion as additional evaluation for left ventricular ejection fractionP1290Assessment of the left atrial appendage systolic function by 3 dimensional transoesophageal echocardiographyP1291Functional anatomy of mitral valve in obstructive hypertrophic cardiomyopathy patientsP1292Right ventricle deformation indices discriminate better than left ventricle deformation indices and fractional shortening between healthy and hypothermia treated asphyxiated neonatesP1293Determinants of myocardial strain in chronic myocardial infarction

2016 ◽  
Vol 17 (suppl 2) ◽  
pp. ii270-ii276
Author(s):  
W-C Tsai ◽  
E. Chamodraka ◽  
N. Behzadnia ◽  
K. Hristova ◽  
A. Ledakowicz-Polak ◽  
...  

2019 ◽  
Vol 6 (4) ◽  
pp. 81-89
Author(s):  
Gowsini Joseph ◽  
Tomas Zaremba ◽  
Martin Berg Johansen ◽  
Sarah Ekeloef ◽  
Einar Heiberg ◽  
...  

The aim of this study was to investigate if there was an association between infarct size (IS) measured by cardiac magnetic resonance (CMR) and echocardiographic global longitudinal strain (GLS) in the early stage of acute myocardial infarction in patients with preserved left ventricular ejection fraction (LVEF). Patients with ST-segment elevation myocardial infarction who underwent primary percutaneous coronary intervention were assessed with CMR and transthoracic echocardiogram within 1 week of hospital admission. Two-dimensional speckle tracking was performed using a semi-automatic algorithm (EchoPac, GE Healthcare). Longitudinal strain curves were generated in a 17-segment model covering the entire left ventricular myocardium. GLS was calculated automatically. LVEF was measured by auto-LVEF in EchoPac. IS was measured by late gadolinium enhancement CMR in short-axis views covering the left ventricle. The study population consisted of 49 patients (age 60.4 ± 9.7 years; 92% male). The study population had preserved echocardiographic LVEF with a mean of 45.8 ± 8.7%. For each percent increase of IS, we found an impairment in GLS by 1.59% (95% CI 0.57–2.61), P = 0.02, after adjustment for sex, age and LVEF. No significant association between IS and echocardiographic LVEF was found: −0.25 (95% CI: −0.61 to 0.11), P = 0.51. At the segmental level, the strongest association between IS and longitudinal strain was found in the apical part of the LV: impairment of 1.69% (95% CI: 1.14–2.23), P < 0.001, for each percent increase in IS. In conclusion, GLS was significantly associated with IS in the early stage of acute myocardial infarction in patients with preserved LVEF, and this association was strongest in the apical part of the LV. No association between IS and LVEF was found.


2019 ◽  
Vol 9 (8) ◽  
pp. 984-992 ◽  
Author(s):  
Pontus Andell ◽  
Stefan James ◽  
Ollie Östlund ◽  
Troels Yndigegn ◽  
David Sparv ◽  
...  

Background: The DETermination of the role of Oxygen in suspected Acute Myocardial Infarction (DETO2X-AMI) trial did not find any benefit of oxygen therapy compared to ambient air in normoxemic patients with suspected acute myocardial infarction. Patients with chronic obstructive pulmonary disease may both benefit and be harmed by supplemental oxygen. Thus we evaluated the effect of routine oxygen therapy compared to ambient air in normoxemic chronic obstructive pulmonary disease patients with suspected acute myocardial infarction. Methods and results: A total of 6629 patients with suspected acute myocardial infarction were randomly assigned in the DETO2X-AMI trial to oxygen or ambient air. In the oxygen group ( n=3311) and the ambient air group ( n=3318), 155 and 141 patients, respectively, had chronic obstructive pulmonary disease (prevalence of 4.5%). Patients with chronic obstructive pulmonary disease were older, had more comorbid conditions and experienced a twofold higher risk of death at one year (chronic obstructive pulmonary disease: 32/296 (10.8%) vs. non-chronic obstructive pulmonary disease: 302/6333 (4.8%)). Oxygen therapy compared to ambient air was not associated with improved outcomes at 365 days (chronic obstructive pulmonary disease: all-cause mortality hazard ratio (HR) 0.99, 95% confidence interval (CI) 0.50–1.99, Pinteraction=0.96); cardiovascular death HR 0.80, 95% CI 0.32–2.04, Pinteraction=0.59); rehospitalisation with acute myocardial infarction or death HR 1.27, 95% CI 0.71–2.28, Pinteraction=0.46); hospitalisation for heart failure or death HR 1.08, 95% CI 0.61–1.91, Pinteraction=0.77]); there were no significant treatment-by-chronic obstructive pulmonary disease interactions. Conclusions: Although chronic obstructive pulmonary disease patients had twice the mortality rate compared to non-chronic obstructive pulmonary disease patients, this prespecified subgroup analysis from the DETO2X-AMI trial on oxygen therapy versus ambient air in normoxemic chronic obstructive pulmonary disease patients with suspected acute myocardial infarction revealed no evidence for benefit of routine oxygen therapy consistent with the main trial’s findings. Clinical Trials Registration: NCT02290080


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