Effects of long-term recombinant bovine somatotropin (bST) administration on milk yield, milk composition and mammary gland health of dairy ewes

1998 ◽  
Vol 29 (1) ◽  
pp. 113-120 ◽  
Author(s):  
C Brozos ◽  
Ph Saratsis ◽  
C Boscos ◽  
S.C Kyriakis ◽  
P Tsakalof
Keyword(s):  
Mammary Gland ◽  
Milk Yield ◽  
Milk Composition ◽  
Bovine Somatotropin ◽  
Recombinant Bovine Somatotropin ◽  
Dairy Ewes

The effect of long-term administration of bovine somatotrophin on the performance of dairy heifers during their first lactation

1988 ◽  
Vol 1988 ◽  
pp. 2-2 ◽  
Author(s):  
R.F. Butterwick ◽  
P. Rowlinson ◽  
T.E.C. Weekes ◽  
D.S. Parker ◽  
D.G. Armstrong
Keyword(s):  
Milk Yield ◽  
Body Condition ◽  
Live Weight ◽  
Milk Composition ◽  
Reproductive Status ◽  
Bovine Somatotropin ◽  
Buffer Solution ◽  
Dairy Heifers ◽  
Term Administration

The objectives of the trial were to Investigate the effects of long-term administration of bovine somatotropin (BST) from week 2 and 10 post-partumn on the yields of milk, milk components, body weight, body condition, health and reproductive status during the first lactation of dairy heifers.19 Friesian dairy cows in their first lactation were allocated at calving to one of 3 treatments: Daily subcutaneous Injection of recomblnantly derived bovine somatotropin (25 mg/d) from either week 2 (BST2;n=6) or week 10 (BST10;n=6) of lactation, or injection of buffer solution from week 2 of lactation (C;n=7). Treatments continued until week 42 of lactation, or until 60 days prior to predicted calving date, if this occurred before week 42 of lactation. Initially cows were housed in cubicles and fed ad libitum individually through calan doors, on a diet of concentrate and grass silage (Table 1) on a 60:40 dry matter ratio. In approximately mid-lactation cows were turned out to grass but continued to receive concentrates according to milk yield and body condition. Milk yield was recorded daily and milk composition twice weekly as were live weight and body condition. Health and reproductive status were monitored over the lactation.

scholarly journals The effectiveness and the consequences of the use of recombinant bovine somatotropin

2018 ◽  
Vol 48 (1) ◽  
pp. 9
Author(s):  
C. N. BROZOS (Χ. Ν. ΜΠΡΟΖΟΣ) ◽  
Ph. SARATSIS (Φ. ΣΑΡΑΤΣΗΣ)
Keyword(s):  
Growth Hormone ◽  
Dairy Cattle ◽  
Milk Yield ◽  
Dominant Role ◽  
Bovine Somatotropin ◽  
Recombinant Bovine Somatotropin ◽  
Commercial Use ◽  
Body Tissues

Growth hormone (also known as somatotropin) plays a dominant role on the development and metabolism of mammalians. Since the early 1950's it has been known that the administration of somatotropin in milk productive animals leads to an increase in milk yield. Nevertheless, its high cost of manufacture didn't allow the massive application, until recently. Genetic engineering achieved the production of recombinant bovine somatotropin (bST) and therefore has permitted the commercial use. Numerous of publications confirm a 10-30% increase in dairy cattle milk yield after bST administration. The mechanism of action of bST involves a series of orchestrated changes in the metabolism of body tissues so that more nutrients can be used for milk synthesis. Long-term bST administration has no effects on animal welfare. The reproductive system od bST treated cows seems to be prone to disorders. These disorders have been found to be insignificant. Advanced quality of management is necessary to accomplish maximum bST response in dairy cattle. BST is homologous to that of sheep and therefore can be successfully used in ewes as well. Due to the large number of dairy ewes in Greece, this is of great importance to Greek animal industry.

scholarly journals Bovine Somatotropin Dose Titration in Lactating Dairy Ewes. 1. Milk Yield and Milk Composition

1995 ◽  
Vol 78 (5) ◽  
pp. 1073-1082 ◽  
Author(s):  
N. Fernandez ◽  
M. Rodriguez ◽  
C. Peris ◽  
M. Barcelo ◽  
M.P. Molina ◽  
...  
Keyword(s):  
Milk Yield ◽  
Milk Composition ◽  
Bovine Somatotropin ◽  
Dose Titration ◽  
Dairy Ewes

scholarly journals Effect of growth hormone on milk yield and reproductive performance of subfertile Holstein cows during extended lactations

2019 ◽  
Vol 17 (1) ◽  
pp. e0403 ◽  
Author(s):  
Jessica Flores ◽  
José E. García ◽  
Jesús Mellado ◽  
Leticia Gaytán ◽  
Ángeles De Santiago ◽  
...  
Keyword(s):  
Milk Yield ◽  
Reproductive Performance ◽  
Bovine Somatotropin ◽  
Holstein Cows ◽  
Control Group ◽  
Recombinant Bovine Somatotropin ◽  
Northern Mexico ◽  
Lactation Length ◽  
Hot Environment ◽  
Farm Efficiency

The objective of this study was to determine the effects of the administration of recombinant bovine somatotropin (rbST) throughout lactation to high-yielding subfertile (conception > 270 days postpartum) Holstein cows undergoing extended lactations (≥480 d) on milk production and reproductive performance. The study used two large adjacent commercial herds with similar management in a hot area of northern Mexico (25° N). Cows in one herd (n=2341) received a 500-mg dose of rbST every 14 d until dried off, starting 60 days postpartum. The other herd served as control (n=984). Across parity, rbST-treated cows produced 20% greater milk yield than control cows in 305-d lactations. Across parities, milk yield from 305 d postpartum to the end of lactation was 2734 kg higher in rbST-treated cows than control cows. Across parities rbST-treated cows produced 4777 more kg of milk during the entire lactation (mean 605 d) than the control group (mean 572 d). Conception rates (CR) at first service were only 3.2% and 5.9% (p<0.05) for control and rbST-treated cows, respectively. Overall CR was 43.5% and 61.6% (p<0.05) for control and treated cows, respectively. Control cows required 2.4 more (p<0.01) services per conception than rbST-treated cows. It was concluded that in this hot environment, the use of rbST suits dairy producers because it substantially improves both milk yield and reproductive performance in subfertile high-yielding Holstein cows. By markedly increasing lactation length and lactation persistency farm efficiency is greatly improved due to extended herd life.

scholarly journals Endocrine control of energy metabolism in the cow: the effect on milk yield and levels of some blood constituents of injecting growth hormone and growth hormone fragments

1980 ◽  
Vol 43 (1) ◽  
pp. 179-188 ◽  
Author(s):  
J. A. Bines ◽  
I. C. Hart ◽  
S. V. Morant
Keyword(s):  
Growth Hormone ◽  
Mammary Gland ◽  
Energy Metabolism ◽  
Dairy Cows ◽  
Milk Yield ◽  
Beef Cows ◽  
Milk Composition ◽  
Endocrine Control ◽  
N Retention ◽  
Blood Constituents

1. Circulating concentrations of some hormones and metabolites and nitrogen balance were measured in lactating beef and dairy cows given daily injections of growth hormone (GH) and were compared to values before injection. Changes in milk yield and composition were recorded in these cows and in additional cows injected with GH fragments.2. GH, but not GH fragments, raised milk yield while milk composition did not change. GH injection caused a large, rapid increase in the level of the hormone in blood and slower, smaller increases in the concentrations of insulin, prolactin and thyroxine. Blood metabolite levels were unaltered except for a rise in glucose concentration in beef cows during GH injection and a fall in 3-hydroxybutyrate concentration in the same cows after the injections ceased. An increase in N output in milk was partly balanced by a reduction in urinary N so that N retention did not change significantly.3. GH caused a reduction in food intake in the beef cows.4. The results are discussed in relation to control of partition of nutrients in the lactating cow, where GH is considered to play an important role. It was concluded that this role may be in increasing the supply of energy metabolites for milk synthesis, rather than a direct effect on the activity of the mammary gland.

scholarly journals Effect of lactation number, year, and season of initiation of lactation on milk yield of cows hormonally induced into lactation and treated with recombinant bovine somatotropin

2011 ◽  
Vol 94 (9) ◽  
pp. 4524-4530 ◽  
Author(s):  
M. Mellado ◽  
E. Antonio-Chirino ◽  
C. Meza-Herrera ◽  
F.G. Veliz ◽  
J.R. Arevalo ◽  
...  
Keyword(s):  
Milk Yield ◽  
Bovine Somatotropin ◽  
Recombinant Bovine Somatotropin
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