A randomized trial comparing whole abdominal radiotherapy with chemotherapy following cisplatinum cytoreduction in epithelial ovarian cancer. West midlands ovarian cancer group trial II

1990 ◽  
Vol 2 (1) ◽  
pp. 4-9 ◽  
Author(s):  
F. Lawton ◽  
D. Luesley ◽  
G. Blackledge ◽  
C. Hilton ◽  
K. Kelly ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Epithelial Ovarian Cancer ◽  
Randomized Trial ◽  
Cancer Group ◽  
West Midlands ◽  
Abdominal Radiotherapy ◽  
Group Trial

scholarly journals Hypodontia phenotype in patients with epithelial ovarian cancer

2015 ◽  
Vol 49 (1) ◽  
pp. 65-70 ◽  
Author(s):  
Anita Fekonja ◽  
Andrej Cretnik ◽  
Danijel Zerdoner ◽  
Iztok Takac
Keyword(s):  
Ovarian Cancer ◽  
Epithelial Ovarian Cancer ◽  
Figo Stage ◽  
Clinicopathological Characteristics ◽  
Control Group ◽  
Malignant Tumours ◽  
Cancer Group ◽  
Significant Difference ◽  
The University ◽  
And Control

Abstract Background. Ovarian cancer is usually diagnosed in an advanced stage and the present clinical and diagnostic molecular markers for early OC screening are insufficient. The aim of this study was to identify potential relationship between the hypodontia and epithelial ovarian cancer (EOC). Patients and methods. A retrospective study was conducted on 120 patients with EOC treated at the Department of Gynaecologic and Breast Oncology at the University Clinical Centre and 120 gynaecological healthy women (control group) of the same mean age. Women in both groups were reviewed for the presence of hypodontia and the patients with EOC also for clinicopathological characteristics of EOC according to hypodontia phenotype. Results. Hypodontia was diagnosed in 23 (19.2%) of patients with EOC and 8 (6.7%) controls (p = 0.004; odds ratio [OR] = 3.32; confidence interval [CI], 1.42-7.76). There was no statistically significant difference in patients with EOC with or without hypodontia regarding histological subtype (p = 0.220); they differed in regard to FIGO stage (p = 0.014; OR =3.26; CI, 1.23-8.64) and tumour differentiation grade (p = 0.042; OR = 3.1; CI, 1.01-9.53). Also, bilateral occurrence of EOC was more common than unilateral occurrence in women with hypodontia (p = 0.021; OR = 2.9; CI, 1.15-7.36). We also found statistically significant difference between the ovarian cancer group and control group in presence of other malignant tumours in subjects (p < 0.001). Conclusions. The results of the study suggest a statistical association between EOC and hypodontia phenotype. Hypodontia might serve as a risk factor for EOC detection.

Whole-abdominal radiotherapy for patients with minimal residual epithelial ovarian cancer

1990 ◽  
Vol 36 (3) ◽  
pp. 338-342 ◽  
Author(s):  
Paul R. Kucera ◽  
Michael L. Herman ◽  
Paul Treadwell ◽  
Ellen E. Sheets ◽  
John P. Micha ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Epithelial Ovarian Cancer ◽  
Abdominal Radiotherapy ◽  
Minimal Residual

A Randomized Trial Comparing Cisplatin Plus Cyclophosphamide Versus Cisplatin, Doxorubicin, and Cyclophosphamide in Advanced Ovarian Cancer

1986 ◽  
Vol 4 (8) ◽  
pp. 1284-1284 ◽  
Author(s):  
P.F. Conte ◽  
M. Bruzzone ◽  
S. Chiara ◽  
M.R. Sertoli ◽  
M.G. Daga ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Epithelial Ovarian Cancer ◽  
Randomized Trial ◽  
Clinical Oncology ◽  
Advanced Ovarian Cancer ◽  
International Federation ◽  
Primary Surgery ◽  
To Receive ◽  
Made In

In the article by Conte et al, "A Randomized Trial Comparing Cisplatin Plus Cyclophosphamide Versus Cisplatin, Doxorubicin, and Cyclophosphamide in Advanced Ovarian Cancer" (Journal of Clinical Oncology 4:965–971, 1986), an error was made in the abstract on page 965 that altered the meaning of a sentence. The correct sentence appears below. After primary surgery, 125 patients with epithelial ovarian cancer (International Federation of Gynaecology and Obstetrics [FIGO] 1c + IIb + IIc = 22 patients, FIGO III = 82 patients, FIGO IV = 21 patients) were randomly allocated to receive PC (cisplatin 50 mg/m2 + cyclophosphamide 600 mg/m2 on day 1 every 28 days) or PAC (PC + doxorubicin 45 mg/m2).

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