416 Cancer-testis Antigen MAGE-C2/CT10 Promotes Proliferation and Resistance to Apoptosis in Multiple Myeloma

2012 ◽  
Vol 48 ◽  
pp. S101
Author(s):  
N. Lajmi ◽  
T. Luetkens ◽  
Y. Cao ◽  
Y. Hildebrandt ◽  
K. Bartels ◽  
...  
Keyword(s):  
Multiple Myeloma ◽  
Cancer Testis Antigen ◽  
Cancer Testis

scholarly journals Cancer-testis antigen MAGE-C1/ CT7 in multiple myeloma: literature review

2020 ◽  
Vol 15 (4) ◽  
pp. 29-37
Author(s):  
E. A. Makunina
Keyword(s):  
Multiple Myeloma ◽  
Germ Cells ◽  
Gene Families ◽  
Transformation Process ◽  
Cancer Testis Antigen ◽  
Hematological Diseases ◽  
Cancer Testis Antigens ◽  
Disease Prognosis ◽  
Tumor Transformation ◽  
Cancer Testis

Group of tumor-associated antigens, which is normally expressed in placental cells and testicular germ cells, is called cancer-testis antigens. To date, more than 40 gene families have been identified that encode cancer-testis antigens, and their expression has been studied in many types of malignant diseases. It is assumed that the expression of cancer-testis antigens can contribute to the development of the tumor transformation process, including hematological diseases. Of particular interest in the pathogenesis of multiple myeloma is the MAGE-C1/CT7 antigen, the expression of which is most often detected in this case. According to data published by various authors, the expression of MAGEC1 in multiple myeloma can be considered as an additional marker of a poor disease prognosis, represent the effectiveness of chemotherapy approaches, and, possibly, be an earlier predictor of relapse or progression.

scholarly journals Over‐Expression of Cancer Testis Antigen Genes in Multiple Myeloma Stem Cell‐like Cells

2013 ◽  
Vol 27 (S1) ◽  
Author(s):  
Jianguo Wen ◽  
Barbara Savoldo ◽  
Youli Zu ◽  
Chung‐Che Chang
Keyword(s):  
Multiple Myeloma ◽  
Stem Cell ◽  
Cancer Testis Antigen ◽  
Over Expression ◽  
Cancer Testis

scholarly journals Cancer-testis antigen MAGE-C2/CT10 induces spontaneous CD4+ and CD8+ T-cell responses in multiple myeloma patients

2014 ◽  
Vol 4 (5) ◽  
pp. e212-e212 ◽  
Author(s):  
H Reinhard ◽  
S Yousef ◽  
T Luetkens ◽  
B Fehse ◽  
B Berdien ◽  
...  
Keyword(s):  
Multiple Myeloma ◽  
T Cell ◽  
T Cell Responses ◽  
Cd8 T Cell ◽  
Cancer Testis Antigen ◽  
Cell Responses ◽  
Cancer Testis

scholarly journals Longitudinal Analysis and Prognostic Effect of Cancer-Testis Antigen Expression in Multiple Myeloma

2009 ◽  
Vol 15 (4) ◽  
pp. 1343-1352 ◽  
Author(s):  
Djordje Atanackovic ◽  
Tim Luetkens ◽  
York Hildebrandt ◽  
Julia Arfsten ◽  
Katrin Bartels ◽  
...  
Keyword(s):  
Multiple Myeloma ◽  
Longitudinal Analysis ◽  
Antigen Expression ◽  
Cancer Testis Antigen ◽  
Prognostic Effect ◽  
Cancer Testis

scholarly journals Cancer-testis antigen SLLP1 represents a promising target for the immunotherapy of multiple myeloma

2015 ◽  
Vol 13 (1) ◽  
Author(s):  
Sara Yousef ◽  
Johanna Heise ◽  
Nesrine Lajmi ◽  
Katrin Bartels ◽  
Nicolaus Kröger ◽  
...  
Keyword(s):  
Multiple Myeloma ◽  
Cancer Testis Antigen ◽  
Promising Target ◽  
Cancer Testis

Expression of cancer-testis antigen in multiple myeloma

2014 ◽  
Vol 34 (2) ◽  
pp. 181-185 ◽  
Author(s):  
Li He ◽  
Jing-na Ji ◽  
Shang-qin Liu ◽  
Er Xue ◽  
Qing Liang ◽  
...  
Keyword(s):  
Multiple Myeloma ◽  
Cancer Testis Antigen ◽  
Cancer Testis

AKAP-4: a novel cancer testis antigen for multiple myeloma

2008 ◽  
Vol 140 (4) ◽  
pp. 465-468 ◽  
Author(s):  
Maurizio Chiriva-Internati ◽  
Raffaele Ferrari ◽  
Yuefei Yu ◽  
Cody Hamrick ◽  
Nicoletta Gagliano ◽  
...  
Keyword(s):  
Multiple Myeloma ◽  
Cancer Testis Antigen ◽  
Cancer Testis

scholarly journals MAGE-C1/CT7 is the dominant cancer-testis antigen targeted by humoral immune responses in patients with multiple myeloma

Leukemia ◽  
2008 ◽  
Vol 22 (8) ◽  
pp. 1646-1648 ◽  
Author(s):  
A Curioni-Fontecedro ◽  
A J Knights ◽  
M Tinguely ◽  
N Nuber ◽  
C Schneider ◽  
...  
Keyword(s):  
Multiple Myeloma ◽  
Immune Responses ◽  
Cancer Testis Antigen ◽  
Humoral Immune ◽  
Humoral Immune Responses ◽  
Cancer Testis
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