A Breast 3D model as a possible tool for non-invasive tumour localization in breast surgery

2020 ◽  
Vol 138 ◽  
pp. S77-S78
Author(s):  
P. Gouveia ◽  
S. Bessa ◽  
H. Oliveira ◽  
E. Batista ◽  
M. Aleluia ◽  
...  
Keyword(s):  
3D Model ◽  
Breast Surgery ◽  
Non Invasive ◽  
Tumour Localization ◽  
Invasive Tumour

scholarly journals Creación de implantes 3D en procesos de conservación y restauración de vidrio arqueológico

2017 ◽  
Vol 8 (16) ◽  
pp. 103 ◽  
Author(s):  
Carmen Díaz-Marín ◽  
Elvira Aura-Castro
Keyword(s):  
3D Model ◽  
Three Dimensional ◽  
Acrylonitrile Butadiene Styrene ◽  
Virtual Model ◽  
Restricted Area ◽  
Non Invasive ◽  
3D Data ◽  
Invasive Method ◽  
Glass Bowl ◽  
Butadiene Styrene

This article describes the restoration of a glass bowl from the 16th-17thcentury by creating its three-dimensional (3D)model. The final purpose is to work with this model in order to avoid damaging situations that are associated with the manipulation of fragile objects. The gap areas, those corresponding to the missing fragments not found in the excavation, were carried out by constructing digital implants. A restricted area of the 3D model has been duplicated in order to accommodate it to confined intervals of the gap. The final implants were printed with acrylonitrile butadiene styrene (ABS) filament. These implants replace the lost areas and give stability back to the item by recovering the original morphology. The result can be compared with the outcome obtained by a traditional process, but differs due to the fact that requires minimum manipulation of the item, so it can contribute to preserve and safeguard the restored object. This is a non-invasive method which is offered as an alternative treatment, where the archaeological object is replaced by its virtual model in the steps of the process after 3D data acquisition. Significant differences have not been found in the 3D printing results obtained with the two types of filaments tested (white and clear).

scholarly journals Breast cancer patient-reported outcome of factors influencing cosmetic satisfaction after breast-conserving therapy

Breast Cancer ◽  
2021 ◽  
Author(s):  
A. T. P. M. Brands-Appeldoorn ◽  
A. J. G. Maaskant-Braat ◽  
L. Janssen ◽  
L. A. D. M. van Osch ◽  
V. C. G. Tjan-Heijnen ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Body Image ◽  
Breast Surgery ◽  
Breast Conserving Therapy ◽  
Patient Reported Outcome ◽  
Breast Size ◽  
Exclusion Criteria ◽  
Non Invasive ◽  
Patient Reported ◽  
Relevant Factors

Abstract Background The aim of this study was to investigate which factors patients considered to be important for determining the degree of cosmetic satisfaction with regards to perceived body image after previous breast-conserving therapy (BCT). Methods Outcomes considered relevant by the patients were first identified using interviews. A questionnaire based on this group input was then devised and added to the physician-based Sneeuw questionnaire. Next, a quantitative study using this questionnaire was conducted in Dutch patients treated at least 6 months earlier for (non-) invasive breast cancer by BCT. Exclusion criteria were: previous mastectomy or BCT of the contralateral breast, BCT with nipple resection, metastatic disease, local recurrence or (previous) plastic breast surgery. Descriptive statistics were used throughout. Results A total of 149 patients (aged 36–87 years) completed the questionnaire. From this focus group input, the top three factors in overall importance (important or very important) for satisfaction were: ‘wearability of bra’ (67%), ‘breast sensitivity’ (59%) and ‘asymmetry’ (51%). Younger patients (< 55 years) considered ‘breast size’ to be most important, whereas ‘wearability of bra’ was most frequently reported by older patients (> 55 years). Time since BCT did not significantly influence the rating of relevant factors. Conclusion Patients consider ‘wearability of bra’, ‘breast sensitivity’ and ‘asymmetry’ as the most important factors when assessing their satisfaction with regards to cosmetic outcome and body image. These factors should be addressed in routine clinical practice during (pre) counseling.

scholarly journals Prognostic values of L-type amino acid transporter 1 and CD98hc expression in breast cancer

2020 ◽  
pp. jclinpath-2020-206457
Author(s):  
Masaaki Ichinoe ◽  
Tetuo Mikami ◽  
Nobuyuki Yanagisawa ◽  
Tsutomu Yoshida ◽  
Kiyomi Hana ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Amino Acid ◽  
Invasive Breast Cancer ◽  
Poor Prognosis ◽  
Growth Factor Receptor ◽  
Amino Acid Transporter ◽  
Breast Cancers ◽  
Non Invasive ◽  
Invasive Tumour ◽  
Acid Transporter

AimsL-type amino acid transporter 1 (LAT1) is a major Na+-independent neutral amino acid transporter, forming a complex with CD98hc. The aim of this study is to investigate the significance of LAT1 and CD98hc in invasive breast cancer.MethodsLAT1 and CD98hc expression was immunohistochemically assessed in 280 invasive breast cancers and analysed for association with clinicopathological features.ResultsHigh levels of LAT1 and CD98hc were observed in triple-negative breast cancers (TNBCs) possessing negative immunoreactivity with oestrogen receptor, progesterone receptor and human epidermal growth factor receptor 2, compared with non-TNBCs (NTNBCs), and were associated with lymph-node metastasis and higher nuclear grade. The high-LAT1-expression group showed a poor prognosis in NTNBC and TNBC, however, high-CD98hc-expression group showed a poor prognosis only in NTNBC. LAT1 and CD98hc expression could be the prognostic factors in univariate analyses, but not in multivariate analyses. Further, we found that invasive tumour components showed higher LAT1 and CD98hc expression than non-invasive tumour components.ConclusionsLAT1 and CD98hc may possess prognostic values in invasive breast cancer. LAT1 may be linked with cancer cell activities and disease progression in breast cancer.

scholarly journals Brightly Colored to Stay in the Dark. Revealing of the Polychromy of the Lot Sarcophagus in the Catacomb of San Sebastiano in Rome

Heritage ◽  
2020 ◽  
Vol 3 (3) ◽  
pp. 858-874
Author(s):  
Susanna Bracci ◽  
Donata Magrini ◽  
Rachele Manganelli del Fà ◽  
Oana Adriana Cuzman ◽  
Barbara Mazzei
Keyword(s):  
Late Antiquity ◽  
3D Model ◽  
Non Invasive ◽  
Naked Eye ◽  
Executive Process ◽  
Different Types ◽  
Yellow Ochre ◽  
Invasive Techniques

The Lot Sarcophagus is one of the most relevant funerary sculptures of late antiquity (mid-4th century AC). Some of the remarkable aspects are the following (i) it is still preserved in situ; (ii) most of the carved scenes are rarities or unicum; (iii) not all the sculpture work has been completed, which allows us to analyse the executive process; (iv) many traces of polychromy have remained. This paper is focused on the characterization of the residual polychromy by using in-situ non-invasive techniques. Furthermore, few micro samples were taken, to be analysed in laboratory to study the composition of some deposits and to define if a preparatory layer was present under the coloured layer. The data showed that the very rich polychromy of the Lot Sarcophagus was made of Egyptian blue, yellow ochre, and three different types of red: two inorganics (red ochre and cinnabar), and one organic-based (madder lake). Furthermore, some decorations, completely vanished and no longer visible to the naked eye, have been rediscovered, also providing details on the construction phases. During the project, the 3D model of the sarcophagus was acquired, which afterwards was used to map the results of the diagnostic campaign.

Computational Fluid Dynamics for Atherosclerosis and Aneurysm Diagnostics

2010 ◽  
Author(s):  
M. A. Al-Rawi ◽  
A. M. Al-Jumaily ◽  
A. Lowe
Keyword(s):  
Fluid Dynamics ◽  
Computational Fluid Dynamics ◽  
Clinical Trials ◽  
Blood Flow ◽  
3D Model ◽  
Flow Model ◽  
Three Dimensional ◽  
Ascending Aorta ◽  
Artery Wall ◽  
Non Invasive

Non-invasive diagnosis of cardiovascular diseases is a valuable tool to reduce patient’s risk and discomfort. The main aim of this work is to investigate the possibilities of using computational fluid dynamics as a tool to investigate the biomechanical characteristics of the aorta under different medical conditions. These conditions include an aorta with healthy conditions, atherosclerosis and aneurysm. A three dimensional pulsatile flow model for an elastic aorta is developed and constructed in ANSYS® CFX 12. Abnormalities are simulated as diameter changes at the root of the ascending aorta. The computational model shows the reflection of these diseases on the blood flow and the artery wall at other locations downstream along the aorta. This 3D model has several advantages over previously published 1D and 2D models by giving more realistic results as compared with clinical trials.

Non-invasive tumour blood perfusion measurement by2H magnetic resonance

2000 ◽  
Vol 13 (8) ◽  
pp. 429-437 ◽  
Author(s):  
L. Bentzen ◽  
M. R. Horsman ◽  
P. Daugaard ◽  
R. J. Maxwell
Keyword(s):  
Magnetic Resonance ◽  
Blood Perfusion ◽  
Perfusion Measurement ◽  
Non Invasive ◽  
Invasive Tumour ◽  
Tumour Blood

The Measurement of 2D Curvature of In-Vivo Human Ear Canal

2008 ◽  
Vol 139 (2_suppl) ◽  
pp. P103-P103
Author(s):  
Jen-Fang Yu ◽  
Fan Chung-chieh ◽  
Chin-Kuo Chen
Keyword(s):  
3D Model ◽  
External Auditory Meatus ◽  
Slice Thickness ◽  
Inferior Wall ◽  
Ear Canal ◽  
High Resolution Computed Tomography ◽  
Non Invasive ◽  
External Canal ◽  
Human Ear

Problem To non-invasively measure the 2D curvature of human ear canal and produce the earmold by the non-invasive 3D ear impression. Methods The images of external ear were scanned by high-resolution computed tomography (HRCT). The resolution for each slice was 512⋉512 pixels. The pixel size was 0.188⋉0.188mm and the slice thickness was 0.625mm. The boundary between tympanic membrane and external auditory meatus was enhanced by image processing. Additionally, 3D model of ear canal was reconstructed by 2D images. The length and angle of first and second bends of canal were measured based on the 3D model. 2D curvature of first and second bends of canal was then computed by sine and cosine laws. Results The volume of ear canal was 862.0 cubic mm. The angle and curvature of superior wall of first bend at axial view were 121.5 degrees and 0.0685; of inferior wall of first bend were 246 degrees and −0.1102; of superior wall of second bend were 227.8 degrees and −0.0332; of inferior wall of second bend were 143.1 degrees and 0.0130 respectively. 2D curvature of superior and inferior wall of first and second bends was diagrammed. Conclusion The 2D curvature of ear canal at first and second bends could be measured and produce the ear impression non-invasively. The geometry of canal changed by tumors is a common syndrome in ear disease. Therefore, the geometry of ear canal can be tracked after the otoplasty. Significance The 3D geometry of canal can help physicians diagnose the syndrome of external canal before otoplasty. Moreover, the hearing aid earmold can be made by non-invasive ear impression instead of invasive ear impression.

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