Toluene Oxyfunctionalization with Air over Metalloporphyrins and Reaction Condition Optimization

2007 ◽  
Vol 15 (3) ◽  
pp. 453-457 ◽  
Author(s):  
Yongfei LI ◽  
Xuhui YAN ◽  
Guofang JIANG ◽  
Qiang LIU ◽  
Jianxin SONG ◽  
...  
Keyword(s):  
Reaction Condition ◽  
Condition Optimization

scholarly journals Virtual Reaction Condition Optimization based on Machine Learning for a Small Number of Experiments in High-dimensional Continuous and Discrete Variables

2019 ◽  
Vol 48 (8) ◽  
pp. 961-964 ◽  
Author(s):  
Mikito Fujinami ◽  
Junji Seino ◽  
Takumi Nukazawa ◽  
Shintaro Ishida ◽  
Takeaki Iwamoto ◽  
...  
Keyword(s):  
Machine Learning ◽  
High Dimensional ◽  
Discrete Variables ◽  
Reaction Condition ◽  
Condition Optimization ◽  
Continuous And Discrete Variables

scholarly journals Reaction condition optimization for non-oxidative conversion of methane using artificial intelligence

2021 ◽  
Author(s):  
Hyun Woo Kim ◽  
Sungwoo Lee ◽  
Gyoung S. Na ◽  
Seung Ju Han ◽  
Seok Ki Kim ◽  
...  
Keyword(s):  
Artificial Intelligence ◽  
Chemical Reactions ◽  
Experimental Methods ◽  
Oxidative Conversion ◽  
Reaction Condition ◽  
Condition Optimization ◽  
Controllable Factors ◽  
Conversion Of Methane ◽  
Oxidative Conversion Of Methane

Chemical reactions typically have numerous controllable factors that need to be optimized to yield the desired products. Although traditional experimental methods are limited to explore possible combinations of these factors,...

Zinc Sulfamate Catalyzed Efficient Selective Synthesis of Benzimidazole Derivatives under Ambient Conditions

2019 ◽  
Vol 16 (9) ◽  
pp. 740-749
Author(s):  
Sushil R. Mathapati ◽  
Arvind H. Jadhav ◽  
Mantosh B. Swami ◽  
Jairaj K. Dawle
Keyword(s):  
Benzimidazole Derivative ◽  
Sulfamic Acid ◽  
Aromatic Aldehydes ◽  
Catalytic Amount ◽  
Product Yield ◽  
Lewis Acidity ◽  
Benzimidazole Derivatives ◽  
Ambient Conditions ◽  
Reaction Condition ◽  
Green Approach

Zinc sulfamate (Zn(NH2SO3)2 is a derivative of sulfamic acid (H3NSO3) which possesses “Lewis acidity” and finds well suited in a number of catalytic applications. The present paper describes an efficient, eco-friendly, and clean synthesis of 2-substituted benzimidazole derivatives by reacting diverse o-phenylenediamine with various substituted aromatic aldehydes using a catalytic amount of zinc sulfamate in ethanol at ambient temperature. As a result, 10 mol.% of Zinc sulfamate catalyst showed 92% of respective product yield with 100% conversion using short reaction period in ethanol. Meanwhile, effect of reaction parameters, such as amount of catalyst, different solvents, and reaction temperature on reaction product, was also studied. In addition, in the optimized reaction condition various substituted biological important benzimidazoles derivatives were prepared by using optimized reaction condition in good to efficient yield. In addition, possible reaction mechanism in the presence of zinc sulfamate for the preparation of benzimidazole derivative was sketched and discussed. The present green approach showed significances with faster reaction rate with inexpensive catalyst, which showed excellent and clean yield of benzimidazole in mild reaction condition with easy work-up procedure.

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