Clinical Experience with Osseous Site Development Using Autogenous Bone, Bone Graft Substitutes, and Membrane Barriers

2001 ◽  
Vol 13 (3) ◽  
pp. 493-509
Author(s):  
Peter K. Moy
2019 ◽  
Vol 48 ◽  
Author(s):  
Mauricio Andrés Tinajero ARONI ◽  
Paulo Firmino da COSTA NETO ◽  
Guilherme José Pimentel Lopes de OLIVEIRA ◽  
Rosemary Adriana Chiérici MARCANTONIO ◽  
Elcio MARCANTONIO JUNIOR

Abstract Introduction The use of bone substitutes in grafting procedures as an alternative of the use of autogenous bone graft has been indicated, however, the direct comparison between these biomaterials has been little explored. Objective To evaluate the effect of different osteoconductive bone substitutes on the bone repair in critical-sized defects (CSDs) in rat calvaria. Material and method One CSD with an 8 mm diameter was made in each of the 40 rats used in this study. The animals were randomly allocated into 5 groups (n=8), according to the type of bone substitute used to fill the CSD: COA (Coagulum); AUT (autogenous bone); DBB (deproteinized bovine bone graft); HA/TCP (biphasic ceramic composed of hydroxyapatite and β-phosphate tricalcium); and TCP (β-phosphate tricalcium). A microtomographic analysis was performed to evaluate the remaining defect linear length (DLL) of the CSD and the volume of the mineralized tissues (MT) within the CSD at 3, 7, 15 and 30 days after the surgical procedure. In addition, a histometric analysis was performed to evaluate the composition of the repaired bone tissue (% Bone and % Biomaterial) at the 30-day period. Result It was shown that the COA had the lowest DLL and MT within the CSD. In addition, the COA presented the highest % of bone in CSD. The DBB had a higher MT and a higher % of bone substitute particles in the CSD than the AUT and TCP groups. The DBB and AUT groups presented higher % of bone in the CSD than the TCP group. Conclusion The use of the DBB promoted a better pattern of bone volume gain and formation compared to TCP and HA / TCP but was biologically inferior to the AUT.


2008 ◽  
Vol 90B (1) ◽  
pp. 131-136 ◽  
Author(s):  
Nina C. Lindfors ◽  
Jouni T. Heikkilä ◽  
Ilona Koski ◽  
Kimmo Mattila ◽  
Allan J. Aho

2021 ◽  
Vol 15 (1) ◽  
pp. 357-365
Author(s):  
Martin Luis S. Redor ◽  
Rui Zhang ◽  
Natthamet Wongsirichat ◽  
Ratchapin Laovanitch Srisatjaluk ◽  
Teeranut Chaiyasamut ◽  
...  

Introduction: There has been extensive research on bone substitutes and autogenous bone; however, little is known about their physical and chemical characteristics of torus mandibularis and palatinus. In the present study, the physical and chemical properties of tori bone and bone graft substitutes were examined. Microbial contamination of torus bone collected during surgery was also investigated. Objective: To investigate the physical and chemical properties of torus mandibularis and torus palatinus, and the microbial contamination of tori bone collected during surgery. Materials and Methods: Torus mandibularis and palatinus were collected from healthy patients by regular surgical procedure via bone collector and a stringent aspiration protocol. Physicochemical properties such as surface structure, elemental components and the crystalline structure of tori and common bone grafting substitutes (OraGRAFT, BioOss, Cerabone) were examined via SEM-EDS, X-Ray Diffractometry analysis, and calcium dissolution assay. The bacterial morphology and gram staining from the torus samples after the surgery were analyzed. Results: The surface structure of tori bone differed greatly from that of bone graft substitutes. An irregular and rough surface structure was found for tori, while bone graft substitutes presented a smooth but dry pattern. Elements found within tori were similar to those within bone graft substitutes; in all cases, carbon, oxygen, sodium, magnesium, phosphate, and calcium were seen. All samples showed high crystallinity, with the highest value in Cerabone, followed by Bio-oss, torus mandibularis, torus palatinus, and Oragraft. Calcium dissolution was highest on the first day in tori samples, whereas it was constantly released until the seventh day in other bone grafts. The microbial contamination was found in all tori samples from the harvesting process, presumably due to saliva contamination. Conclusion: Tori bone was different from bone graft substitutes in terms of surface structure, crystallinity, and calcium release. However, tori bone and bone graft substitutes were similar in terms of elemental composition and crystal compounds, which may positively affect their clinical applications. Taken together, our findings suggest that with an effective decontamination, tori bone should be considered as a viable material for bone grafting, as it is not only practical but also cost-efficient for patients.


2005 ◽  
Vol 18 (03) ◽  
pp. 157-168 ◽  
Author(s):  
H. C. Dorea ◽  
H. D. Cantwell ◽  
R. Read ◽  
L. Armbrust ◽  
R. Pool ◽  
...  

SummaryCancellous bone grafting is a widely accepted technique in human and veterinary orthopaedic surgery. However, the use of autogenous bone graft is limited by the additional surgical time required to harvest the graft, the morbidity associated with the donor site, and the limited availability of cancellous bone, especially in feline patients. Various allografts and bone graft substitutes are available commercially but have not been fully evaluated for efficacy in the cat. The purpose of this study was to compare the incorporation of autogenous and allogenous cancellous bone graft and Bioglass®, a synthetic bone graft substitute, in femoral defects in cats. Four (4.0 mm diameter) defects were created in the lateral diaphyseal cortex of the left femur with an orthopaedic drill. In each femur, one of the cortical defects was filled with autogenous cancellous graft (harvested from the tibia), one was filled with allogenic cancellous graft, and one was filled with Bioglass. The fourth defect remained unfilled. Graft incorporation within the femoral defects was evaluated by radiographic evaluation every two weeks. Six weeks after the grafting procedure, the cats were euthanatized and high detailed radiography, dual energy X-ray absorptiometry (DEXA), histopathology and histomorphometry of the defects were performed. Satisfactory bone healing was observed within all of the defects.


RSBO ◽  
2017 ◽  
Vol 1 (2) ◽  
pp. 114
Author(s):  
Priscila Alves Teixeira ◽  
Carmen L. Mueller Storrer ◽  
Felipe Rychuv Santos ◽  
Aline Monise Sebastiani ◽  
Tatiana Miranda Deliberador

The periodontal treatment of teeth with furcation defect is clinically challenging. In cases of class II furcation defects, the regenerative surgery shows low morbidity and good prognosis when correctly indicated. The aim of the presentstudy is to report a treatment option for class II furcation defect through autogenous bone graft associated with the Bichat’s fat pad. Case report: A 59-year-old female patient was diagnosed with class II furcation defect in the left mandibular first molar. The treatment comprised surgical reconstruction of the defect with a combination of maxillary tuberosity bone graft and Bichat’s fat pad. The clinical and radiographic follow-up of 180 days showed bone formation inthe furcation area and absence of probing depth. Conclusion: An association of autogenous graft form the maxillary tuberosity with a Bichat’s fat pad proved to be a safe, low cost, and effective therapy for the regenerative treatment of class II furcation.


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