Biocompatibility of an experimental glass-ionomer cement sealer in rat mandibular bone

Experimental glass ionomer cement was prepared for the purpose of this study. Twenty disk specimens (16mm diameter x 10mm height) of test-GIC were prepared for the diametral tensile strength (DTS) test and twenty cylindrical specimens (6 mm diameter x 16mm height) were prepared for the compressive strength (CS) test. Specimens were stored in an artificial saliva at 37º C and (50±10%) of relative humidity in an incubator until testing. Five specimens of each GIC were submitted to CS and DTS test in each period, namely 1 hour, 24 hours, 7 days and 28 days. The specimens were tested in a Universal Testing Machine (Instron 1122, Instron corp., High Wycombe, U.K.) at a crosshead speed of 1.0mm/min for CS and 0.5mm/min for the DTS test until failure occurred. The results have revealed that incorporation of lithium fluoride in the formula of the test GIC might impart an increase in the mechanical properties of the GICs

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Resistance of experimental glass ionomer cement sealers to bacterial penetration in vitro

Journal of Endodontics ◽

10.1016/s0099-2399(99)80121-6 ◽

1999 ◽

Vol 25 (11) ◽

pp. 739-742 ◽

Cited By ~ 7

Author(s):

Ian G. McDougall ◽

Vivek Patel ◽

Paul Santerre ◽

Shimon Friedman

Keyword(s):

Glass Ionomer Cement ◽

Glass Ionomer ◽

Experimental Glass ◽

Bacterial Penetration ◽

Ionomer Cement

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Physical Properties of Glass Ionomer Cement Containing Pre-Reacted Spherical Glass Fillers

Brazilian Dental Journal ◽

10.1590/0103-6440202003276 ◽

2020 ◽

Vol 31 (4) ◽

pp. 445-452

Author(s):

Piyaphong Panpisut ◽

Naruporn Monmaturapoj ◽

Autcharaporn Srion ◽

Arnit Toneluck ◽

Prathip Phantumvanit

Keyword(s):

Glass Ionomer Cement ◽

Deionized Water ◽

Fluoride Release ◽

Glass Ionomer ◽

Mass Ratio ◽

Salt Formation ◽

Experimental Glass ◽

Liquid Phases ◽

Glass Fillers ◽

Ionomer Cement

Abstract The aim of this study was to assess the effect of different commercial liquid phases (Ketac, Riva, and Fuji IX) and the use of spherical pre-reacted glass (SPG) fillers on cement maturation, fluoride release, compressive (CS) and biaxial flexural strength (BFS) of experimental glass ionomer cements (GICs). The experimental GICs (Ketac_M, Riva_M, FujiIX_M) were prepared by mixing SPG fillers with commercial liquid phases using the powder to liquid mass ratio of 2.5:1. FTIR-ATR was used to assess the maturation of GICs. Diffusion coefficient of fluoride (DF) and cumulative fluoride release (CF) in deionized water was determined using the fluoride ion specific electrode (n=3). CS and BFS at 24 h were also tested (n=6). Commercial GICs were used as comparisons. Riva and Riva_M exhibited rapid polyacrylate salt formation. The highest DF and CF were observed with Riva_M (1.65x10-9 cm2/s) and Riva (77 ppm) respectively. Using SPG fillers enhanced DF of GICs on average from ~2.5x10-9 cm2/s to ~3.0x10-9 cm2/s but reduced CF of the materials on average from ~51 ppm to ~42 ppm. The CS and BFS of Ketac_M (144 and 22 MPa) and Fuji IX_M (123 and 30 MPa) were comparable to commercial materials. Using SPG with Riva significantly reduced CS and BFS from 123 MPa to 55 MPa and 42 MPa to 28 MPa respectively. The use of SPG fillers enhanced DF but reduced CF of GICs. Using SPG with Ketac or Fuji IX liquids provided comparable strength to the commercial materials.

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Antimicrobial Effect of an Experimental Glass Ionomer Cement against Pathogens associated with Deep Carious Lesions

The Journal of Contemporary Dental Practice ◽

10.5005/jp-journals-10024-2342 ◽

2018 ◽

Vol 19 (7) ◽

pp. 824-829

Author(s):

Fawaz Siddiqui ◽

Kalepu Vamsi

Keyword(s):

Glass Ionomer Cement ◽

Antimicrobial Effect ◽

Glass Ionomer ◽

Experimental Glass ◽

Carious Lesions ◽

Deep Carious Lesions ◽

Ionomer Cement

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Synthesis and biocompatibility of an experimental glass ionomer cement prepared by a non-hydrolytic sol-gel method

Brazilian Dental Journal ◽

10.1590/s0103-64402010000600004 ◽

2010 ◽

Vol 21 (6) ◽

pp. 499-507 ◽

Cited By ~ 8

Author(s):

Lucas da Fonseca Roberti Garcia ◽

Fernanda de Carvalho Panzeri Pires-de-Souza ◽

Juliana Mazzoneto Teófilo ◽

Alexandre Cestari ◽

Paulo Sergio Calefi ◽

...

Keyword(s):

Inflammatory Reaction ◽

Sol Gel ◽

Glass Ionomer Cement ◽

Control Group ◽

Glass Ionomer ◽

Gel Method ◽

Sol Gel Method ◽

Experimental Glass ◽

Chronic Inflammatory Reaction ◽

Ionomer Cement

The aims of this study were to demonstrate the synthesis of an experimental glass ionomer cement (GIC) by the non-hydrolytic sol-gel method and to evaluate its biocompatibility in comparison to a conventional glass ionomer cement (Vidrion R). Four polyethylene tubes containing the tested cements were implanted in the dorsal region of 15 rats, as follows: GI - experimental GIC and GII - conventional GIC. The external tube walls was considered the control group (CG). The rats were sacrificed 7, 21 and 42 days after implant placement for histopathological analysis. A four-point (I-IV) scoring system was used to graduate the inflammatory reaction. Regarding the experimental GIC sintherization, thermogravimetric and x-ray diffraction analysis demonstrated vitreous material formation at 110oC by the sol-gel method. For biocompatibility test, results showed a moderate chronic inflammatory reaction for GI (III), severe for GII (IV) and mild for CG (II) at 7 days. After 21 days, GI presented a mild reaction (II); GII, moderate (III) and CG, mild (II). At 42 days, GI showed a mild/absent inflammatory reaction (II to I), similar to GII (II to I). CG presented absence of chronic inflammatory reaction (I). It was concluded that the experimental GIC presented mild/absent tissue reaction after 42 days, being biocompatible when tested in the connective tissue of rats.

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