528 THE ROLE OF NATURAL COMPOUND D161 IN NEUROGENIC INFLAMMATION

2009 ◽  
Vol 13 (S1) ◽  
Author(s):  
A.R. Lupu ◽  
L. Cremer ◽  
F. Kerek ◽  
A. Calugaru ◽  
N.S. Barzu ◽  
...  
Keyword(s):  
Natural Compound ◽  
Neurogenic Inflammation

scholarly journals Psychological and biological background of the interaction between psoriasis and stress

2014 ◽  
Vol 155 (24) ◽  
pp. 939-948 ◽  
Author(s):  
L. János Kálmán ◽  
Xénia Gonda ◽  
Lajos Kemény ◽  
Zoltán Rihmer ◽  
Zoltán Janka
Keyword(s):  
Neurogenic Inflammation ◽  
Significant Proportion ◽  
Stress Perception ◽  
Exact Role ◽  
New Techniques ◽  
The Past ◽  
Psychotherapeutic Interventions ◽  
Objective Evidence ◽  
Long Time

Stress is considered as a major contributor to the development and exacerbation of psoriasis by a significant proportion of patients and dermatologists. As both stressor and its effects are subject-dependent, thus extremely difficult to measure, our understanding of the exact role of stress in disease development was limited for a long time. In the past decade several new studies were carried out which expanded our knowledge on the pathophysiologic processes linking stress to psoriasis via with their objective measurements and the applied new techniques. The authors review the current literature of both psychological (alexithymia, personality, affect) and biological (cortisol, epinephrine, neurogenic inflammation) factors influencing stress perception and response in psoriasis. Results of recent investigations support previous reports about the interaction between stress and psoriasis with objective evidence. Knowing how effective stress-reducing psychopharmacologic and psychotherapeutic interventions are in the treatment of psoriasis the authors hope that this review contributes to a wider acceptance of the psychosomatic attitude in everyday dermatologic practice. Orv. Hetil., 2014, 155(24), 939–948.

Erratum: New aspects on the role of kinins in neurogenic inflammation

1995 ◽  
Vol 73 (9) ◽  
pp. 1292-1292
Author(s):  
Pierangelo Geppetti ◽  
Claude Bertrand ◽  
Fabio L. M. Ricciardolo ◽  
Jay A. Nadel
Keyword(s):  
Neurogenic Inflammation

Role of substance P (SP) in development of symptoms of neurogenic inflammation in the oral mucosa of the rat

1993 ◽  
Vol 28 (3) ◽  
pp. 191-196 ◽  
Author(s):  
A. Gyorfi ◽  
A. Fazekas ◽  
F. Irmes ◽  
G. Jakab ◽  
T. Suto ◽  
...  
Keyword(s):  
Substance P ◽  
Oral Mucosa ◽  
Neurogenic Inflammation

Effect of S-methylmethionine on the photosynthesis in maize at different chilling temperatures

2011 ◽  
Vol 6 (1) ◽  
pp. 75-83 ◽  
Author(s):  
Eszter Kósa ◽  
Dóra Szegő ◽  
Eszter Horváth ◽  
Ilona Rácz ◽  
Zoltán Szigeti ◽  
...  
Keyword(s):  
Natural Compound ◽  
Chilling Stress ◽  
Photosynthetic Apparatus ◽  
Net Photosynthesis ◽  
Variable Fluorescence ◽  
Similar Tendency ◽  
Chilling Temperatures ◽  
Maize Plants ◽  
Stress Damage

AbstractThe effect of the natural compound S-methylmethionine (SMM) on the functioning of the photosynthetic apparatus, the efficiency of photosynthesis and the synthesis of stress-induced phenoloids and anthocyanins involved in defence was investigated in young maize plants exposed to moderate and severe chilling stress. Damage to PSII was observed as a reduction in the value of variable fluorescence (Fv/Fm) which could be detected even after few hours of mild chilling stress. At temperatures below 10°C, the reduction in Fv/Fm was more pronounced. Changes in the value of net photosynthesis exhibited a similar tendency. SMM has a moderating effect on this reduction and its protective effect was more pronounced under long-lasting chilling stress and at the lowest temperatures. Monitoring of fluorescence intensities and ratios correlated with the levels of stress defence compounds. The fluorescence intensities were found to increase over the course of chilling stress in response to SMM, with the highest values being recorded in plants exposed to the longest period of stress. A similar tendency was observed for the quantity of anthocyanins. The results confirm the complex role of SMM, which is manifested both in preserving the ability of the photosynthetic apparatus to function and in stimulating the synthesis of metabolites involved in stress defence.

scholarly journals Role of Mast Cells in the Pathogenesis of Pruritus in Mastocytosis

2021 ◽  
Author(s):  
Dominika Kwiatkowska ◽  
Adam Reich
Keyword(s):  
Mast Cells ◽  
Neurogenic Inflammation ◽  
Treatment Options ◽  
Sensory Nerve ◽  
Neurokinin A ◽  
Calcitonin Gene ◽  
Abnormal Accumulation ◽  
Mutual Communication

Pruritus can be defined as an unpleasant sensation that evokes a desire to scratch and significantly impairs patients’ quality of life. Pruritus is widely observed in many dermatoses, including mastocytosis, a rare disease characterized by abnormal accumulation of mast cells, which can involve skin, bone marrow, and other organs. Increasing evidence highlights the role of mast cells in neurogenic inflammation and itching. Mast cells release various pruritogenic mediators, initiating subsequent mutual communication with specific nociceptors on sensory nerve fibres. Among important mediators released by mast cells that induce pruritus, one can distinguish histamine, serotonin, proteases, as well as various cytokines. During neuronal-induced inflammation, mast cells may respond to numerous mediators, including neuropeptides, such as substance P, neurokinin A, calcitonin gene-related peptide, endothelin 1, and nerve growth factor. Currently, treatment of pruritus in mastocytosis is focused on alleviating the effects of mediators secreted by mast cells. However, a deeper understanding of the intricacies of the neurobiology of this disease could help to provide better treatment options for patients.

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