Calcium Reduces Fractures in Healthy Women

ABSTRACT 10 mg/kg of dibutyryl cyclic adenosine 3′,5′-monophosphate (Db-cAMP) was iv pulse injected into twelve healthy adult women. The plasma cortisol levels were determined as 11-OHCS at zero time and then at 2.5, 5, 7.5, 10, 15, 30, 60 and 180 min after the injection. The data were compared with those obtained at the corresponding times in two groups of eleven and seventeen healthy women after the injection of 250 ng and 250 μg of synthetic β-1-24 corticotrophin performed in the same manner as the injection of the nucleotide. The mean increments in plasma cortisol were significantly lower after Db-cAMP than after ACTH. Differences were noted by analyzing the time course of the responses. In the case of stimulation with Db-cAMP the 11-OHCS levels rose progressively to a maximum at 15–30 min. By contrast, a peak of plasma cortisol was evident in most cases within a few min after the injection of ACTH; after a fall, a later rise was then observed starting from 15 min. The differences in the plasma 11-OHCS responses after the two stimuli may also be of interest clinically for the investigation of some aspects of adrenal steroidogenesis.

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Pituitary responses to a dopamine antagonist at different times of the day in normal women

Acta Endocrinologica ◽

10.1530/acta.0.1000481 ◽

1982 ◽

Vol 100 (4) ◽

pp. 481-485 ◽

Cited By ~ 5

Author(s):

F. R. Pérez-López ◽

C. M. González-Moreno ◽

M. D. Abós ◽

J. A. Andonegui ◽

R. H. Corvo

Keyword(s):

Serum Prolactin ◽

Dopamine Antagonist ◽

Hormonal Changes ◽

Healthy Women ◽

Serum Lh ◽

Normal Women ◽

The Times ◽

Serum Tsh

Abstract. In order to determine whether or not pituitary responsiveness to the dopaminergic antagonist clebopride changes during the nyctohemeral cycle, 10 healthy women with regular cycles were given 1 mg of clebopride orally at 09.00 h and 24.00 h with at least a 5 day interval between each test. In addition, 5 of the women were given a placebo instead of clebopride at midnight to evaluate the spontaneous hormonal changes. During the 24.00 h test the women had significantly higher P < 0.05) mean TSH basal levels. Serum prolactin (Prl) increased significantly (P < 0.001) after clebopride administration while these changes did not occur when placebo was used instead of clebopride at midnight. The Prl response to clebopride was qualitatively similar at 09.00 h and at 24.00 h. Clebopride given at midnight induced a significant increase (P < 0.05) in serum TSH while this change did not occur when the drug was given at 09.00 h or when placebo was given at midnight. The administration of clebopride resulted in no discernible alterations in serum LH, FSH or GH in either the 09.00 h or the 24.00 h tests. Thus, Prl responses to clebopride were similar in the morning and at midnight, TSH significantly increased after clebopride at midnight whereas this did not occur when the drug was given in the morning, and no significant changes were induced in LH, FSH or GH at the times studied.

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Repeated-sprint training under cyclic hypoxia improves body composition in healthy women

The Journal of Sports Medicine and Physical Fitness ◽

10.23736/s0022-4707.18.09368-4 ◽

2019 ◽

Vol 59 (10) ◽

Author(s):

Marta Camacho-Cardenosa ◽

Alba Camacho-Cardenosa ◽

Javier Brazo-Sayavera ◽

Samantha Guerrero-Flores ◽

Guillermo Olcina ◽

...

Keyword(s):

Body Composition ◽

Sprint Training ◽

Healthy Women ◽

Repeated Sprint

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Neurokinin B receptor antagonism suppresses ovarian follicle growth and delays ovulation in healthy women

10.26226/morressier.573c1514d462b80296c98ccc ◽

2016 ◽

Author(s):

Richard Anderson

Keyword(s):

Ovarian Follicle ◽

Follicle Growth ◽

Neurokinin B ◽

Receptor Antagonism ◽

Healthy Women

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Knee flexor muscle strength is related to gait performance in women with multiple sclerosis but not for healthy women

10.26226/morressier.59a3e8b7d462b8028d8958a3 ◽

2017 ◽

Author(s):

Cintia Ramari

Keyword(s):

Multiple Sclerosis ◽

Muscle Strength ◽

Flexor Muscle ◽

Gait Performance ◽

Knee Flexor ◽

Healthy Women

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Features of the ovarian reserve of women of reproductive age suffering from autoimmune diseases

GYNECOLOGY ◽

10.26442/20795696.2020.5.200416 ◽

2020 ◽

Vol 22 (5) ◽

pp. 27-30

Author(s):

Elena N. Andreeva ◽

Olga R. Grigoryan ◽

Yulia S. Absatarova ◽

Irina S. Yarovaya ◽

Robert K. Mikheev

Keyword(s):

Type 1 Diabetes ◽

Thyroid Gland ◽

Autoimmune Diseases ◽

Ovarian Reserve ◽

Reproductive Potential ◽

Reproductive Age ◽

Control Group ◽

Antithyroid Antibodies ◽

Healthy Women

The reproductive potential of a woman depends on indicators of the ovarian reserve, such as the anti-Muller hormone (AMH) and the number of antral follicles (NAF). Autoimmune diseases have a significant effect on fertility and contribute to the development of premature ovarian failure. Aim.To evaluate the parameters of the ovarian reserve in patients with type 1 diabetes mellitus, carriers of antibodies to the thyroid gland in a state of euthyroidism and compare them with similar parameters in healthy women. Materials and methods.In the first block of the study, the level of AMH, follicle-stimulating hormone, luteinizing hormone, NAF was studied among 224 women with diabetes and 230 healthy women in the control group. In block II, the level of the above hormonal indices was studied in 35 carriers of antithyroid antibodies in the state of euthyroidism and 35 healthy women. Results.In patients with type 1 diabetes, the level of AMH, NAF was statistically significantly lower when compared with the control group. Among carriers of antithyroid antibodies and healthy women, no difference in AMH and NAF was found. Conclusion.The autoimmune processes accompanying diabetes are more influenced by the ovarian reserve indices than autoimmune aggression to the tissues of the thyroid gland.

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