scholarly journals EORTC-related new drug discovery and development activities: role of the Pharmacology and Molecular Mechanisms Group

2012 ◽  
Vol 10 (1) ◽  
pp. 128-140 ◽  
Author(s):  
G.J. Peters ◽  
E. Chatelut ◽  
A.K. Larsen ◽  
N. Zaffaroni
Keyword(s):  
Drug Discovery ◽  
Molecular Mechanisms ◽  
Drug Discovery And Development ◽  
New Drug

Challenges in Alzheimer's Disease Drug Discovery and Development: The Role of Modeling, Simulation, and Open Data

2020 ◽  
Vol 107 (4) ◽  
pp. 796-805 ◽  
Author(s):  
Daniela J. Conrado ◽  
Sridhar Duvvuri ◽  
Hugo Geerts ◽  
Jackson Burton ◽  
Carla Biesdorf ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Drug Discovery ◽  
Open Data ◽  
Drug Discovery And Development ◽  
Modeling Simulation

Role of drug metabolism in drug discovery and development

2001 ◽  
Vol 21 (5) ◽  
pp. 397-411 ◽  
Author(s):  
Gondi N. Kumar ◽  
Sekhar Surapaneni
Keyword(s):  
Drug Discovery ◽  
Drug Metabolism ◽  
Drug Discovery And Development

The Evolving Role of Drug Metabolism in Drug Discovery and Development

2007 ◽  
Vol 24 (5) ◽  
pp. 842-858 ◽  
Author(s):  
Lilian G. Yengi ◽  
Louis Leung ◽  
John Kao
Keyword(s):  
Drug Discovery ◽  
Drug Metabolism ◽  
Drug Discovery And Development

The impact of molecular biology on drug discovery

2006 ◽  
Vol 34 (2) ◽  
pp. 313-316 ◽  
Author(s):  
G.P. Belfield ◽  
S.J. Delaney
Keyword(s):  
Drug Discovery ◽  
Molecular Biology ◽  
Clinical Efficacy ◽  
Drug Targets ◽  
Safety Data ◽  
Vital Role ◽  
Drug Discovery And Development ◽  
New Drug ◽  
Whole Process ◽  
The Impact

The discipline of molecular biology has become increasingly important in recent times for the process of drug discovery. We describe the impact of molecular biology across the whole process of drug discovery and development, including (i) the identification and validation of new drug targets, (ii) the development of molecular screens to find new candidate drugs, and (iii) the generation of safety data and competences leading to enhanced clinical efficacy. We also speculate on emerging developments in drug discovery where it seems likely that molecular biology will play an even more vital role in the generation of future therapies.

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