The protective role of thiola and soybean seeds against the genotoxicity induced by potassium dichromate in mice

2002 ◽  
Vol 517 (1-2) ◽  
pp. 1-12 ◽  
Author(s):  
Maha A. Fahmy ◽  
Hoda M. Shoman ◽  
Entesar E.S. Hassan
Keyword(s):  
Potassium Dichromate ◽  
Protective Role ◽  
Soybean Seeds

scholarly journals Protective Role of Agrimonia eupatoria L. in Heavy Metal Induced Nephrotoxicity

2018 ◽  
Vol 62 (2) ◽  
pp. 13-18
Author(s):  
D. Marcinčáková ◽  
M. Falis ◽  
P. Schusterová ◽  
P. Váczi ◽  
S. Marcinčák ◽  
...  
Keyword(s):  
Heavy Metal ◽  
Potassium Dichromate ◽  
Ethanolic Extract ◽  
Protective Role ◽  
Rabbit Kidney ◽  
Cell Adherence ◽  
Metal Compounds ◽  
Sulfate Heptahydrate ◽  
Chloride Dihydrate

Abstract The aim of this study was to evaluate the potential protective role of Agrimonia eupatoria L. in heavy metal induced nephrotoxicity. Rabbit kidney epithelial cells (RK13) were used as the model cell line. They were exposed to three different heavy metal compounds: cadmium chloride dihydrate CdCl2.2H2O (15 and 20 mg.l−1), potassium dichromate K2Cr2O7 (1, 10 mg.l−1), and zinc sulfate heptahydrate ZnSO4.7H2O (50, 150 mg.l−1) simultaneously with agrimony (ethanolic extract, 100 mg.l−1). The cell response was recorded using the xCELLigence system or real-time cell analysis (RTCA) as a cell index (CI) and expressed as cell adherence (%) compared to control cells without treatment. The potential nephroprotective effects were recorded in cells treated with chromium (1 a 10 mg.l−1) and agrimony, where the cell adherence increased from 95.11 ± 11.25 % and 7.24 ± 0.33 % to 103.26 ± 1.23 % and 68.54 ± 4.89 % (P < 0.05) respectfully and also with a combination of agrimony and zinc (150 mg.l−1), where the adherence increased from 57.45 ± 1.98 % to 95.4 ± 6.95 %. During the cell exposure to cadmium in combination with agrimony, the protective effect was not recorded; the adherence of cells was even decreased (P < 0.05).

scholarly journals Structural Changes Induced by Potassium Dichromate in Renal Cortex of Adult Male Albino Rats and the Possible Protective Role of Selenium

2019 ◽  
Vol 87 (March) ◽  
pp. 661-675
Author(s):  
ALSHYMAA O.H. AHMED, M.Sc. HANAN E.L. MOKHTAR, M.D. ◽  
HEBA O.M. HELMY, M.D. SAMAA S. ABD EL-FATAH, M.D.
Keyword(s):  
Adult Male ◽  
Structural Changes ◽  
Renal Cortex ◽  
Potassium Dichromate ◽  
Protective Role ◽  
Albino Rats

scholarly journals The Protective Role of Thiola against the Genotoxic Effect of Potassium Dichromate in Mice in vivo.

CYTOLOGIA ◽  
2001 ◽  
Vol 66 (1) ◽  
pp. 45-53 ◽  
Author(s):  
Maha A. Fahmy ◽  
Soheir Abdel-Kawy ◽  
Entesar E. S. Hassan
Keyword(s):  
Potassium Dichromate ◽  
Protective Role ◽  
Genotoxic Effect

Protective role of peroxiredoxin-4 in heart failure

2020 ◽  
Vol 134 (1) ◽  
pp. 71-72
Author(s):  
Naseer Ahmed ◽  
Masooma Naseem ◽  
Javeria Farooq
Keyword(s):  
Heart Failure ◽  
Cardiac Fibroblasts ◽  
Protective Role ◽  
Oxidative Stress Markers ◽  
Stress Markers ◽  
Total Antioxidant ◽  
Galectin 3 ◽  
Consequent Increase ◽  
And Oxidative Stress

Abstract Recently, we have read with great interest the article published by Ibarrola et al. (Clin. Sci. (Lond.) (2018) 132, 1471–1485), which used proteomics and immunodetection methods to show that Galectin-3 (Gal-3) down-regulated the antioxidant peroxiredoxin-4 (Prx-4) in cardiac fibroblasts. Authors concluded that ‘antioxidant activity of Prx-4 had been identified as a protein down-regulated by Gal-3. Moreover, Gal-3 induced a decrease in total antioxidant capacity which resulted in a consequent increase in peroxide levels and oxidative stress markers in cardiac fibroblasts.’ We would like to point out some results stated in the article that need further investigation and more detailed discussion to clarify certain factors involved in the protective role of Prx-4 in heart failure.

Parenting Behaviors and Anxiety in Young Adults

2015 ◽  
Vol 36 (3) ◽  
pp. 170-176 ◽  
Author(s):  
Erin N. Stevens ◽  
Joseph R. Bardeen ◽  
Kyle W. Murdock
Keyword(s):  
Effortful Control ◽  
Parenting Behaviors ◽  
Protective Role ◽  
Anxiety Symptoms ◽  
Interactive Effects ◽  
Parental Overprotection ◽  
High Control ◽  
Development Of Anxiety ◽  
The Relationship

Parenting behaviors – specifically behaviors characterized by high control, intrusiveness, rejection, and overprotection – and effortful control have each been implicated in the development of anxiety pathology. However, little research has examined the protective role of effortful control in the relation between parenting and anxiety symptoms, specifically among adults. Thus, we sought to explore the unique and interactive effects of parenting and effortful control on anxiety among adults (N = 162). Results suggest that effortful control uniquely contributes to anxiety symptoms above and beyond that of any parenting behavior. Furthermore, effortful control acted as a moderator of the relationship between parental overprotection and anxiety, such that overprotection is associated with anxiety only in individuals with lower levels of effortful control. Implications for potential prevention and intervention efforts which specifically target effortful control are discussed. These findings underscore the importance of considering individual differences in self-regulatory abilities when examining associations between putative early-life risk factors, such as parenting, and anxiety symptoms.

Sign in / Sign up

Export Citation Format

Share Document