129. The Role of S/MAR on the Efficiency of Ocular Non-Viral Gene Delivery to the RPE

Synthesis of long-chain hyperbranched poly(ethylenimine-co-oxazoline)s by AB2 thiol–yne chemistry is reported, and their application as pDNA transfection agents studied.

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Poly(ethylene glycol)/poly(ε-caprolactone) diblock copolymeric nanoparticles for non-viral gene delivery: The role of charge group and molecular weight in particle formation, cytotoxicity and transfection

Journal of Controlled Release ◽

10.1016/j.jconrel.2006.03.021 ◽

2006 ◽

Vol 113 (2) ◽

pp. 173-182 ◽

Cited By ~ 28

Author(s):

Jeong Soon Jang ◽

So Yeon Kim ◽

Sang Bong Lee ◽

Kyung Ok Kim ◽

Joong Soo Han ◽

...

Keyword(s):

Molecular Weight ◽

Gene Delivery ◽

Ethylene Glycol ◽

Particle Formation ◽

Viral Gene ◽

Poly Ethylene Glycol ◽

Poly Ethylene ◽

Viral Gene Delivery

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Chitosan in Non-Viral Gene Delivery: Role of Structure, Characterization Methods, and Insights in Cancer and Rare Diseases Therapies

Polymers ◽

10.3390/polym10040444 ◽

2018 ◽

Vol 10 (4) ◽

pp. 444 ◽

Cited By ~ 32

Author(s):

Beatriz Santos-Carballal ◽

Elena Fernández Fernández ◽

Francisco Goycoolea

Keyword(s):

Gene Delivery ◽

Rare Diseases ◽

Structure Characterization ◽

Viral Gene ◽

Characterization Methods ◽

Viral Gene Delivery

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A small, bifunctional synthetic peptide for non-viral gene delivery to hepatocytes via the serpin-enzyme complex receptor

Journal of Hepatology ◽

10.1016/s0168-8278(01)80322-6 ◽

2001 ◽

Vol 34 (0) ◽

pp. 91

Author(s):

S Patel

Keyword(s):

Gene Delivery ◽

Synthetic Peptide ◽

Viral Gene ◽

Enzyme Complex ◽

Complex Receptor ◽

Viral Gene Delivery

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Faculty Opinions recommendation of Actin cytoskeleton as the principal determinant of size-dependent DNA mobility in cytoplasm: a new barrier for non-viral gene delivery.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1023279.270637 ◽

2005 ◽

Author(s):

Yu-Li Wang

Keyword(s):

Gene Delivery ◽

Actin Cytoskeleton ◽

Viral Gene ◽

Size Dependent ◽

Dna Mobility ◽

Viral Gene Delivery

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Recent advances in the analysis full/empty capsid ratio and genome integrity of adeno-associated virus (AAV) gene delivery vectors

Current Molecular Medicine ◽

10.2174/1566524020999200730181042 ◽

2020 ◽

Vol 20 ◽

Author(s):

L. Hajba ◽

A. Guttman

Keyword(s):

Gene Delivery ◽

High Efficiency ◽

Analytical Techniques ◽

Viral Gene ◽

Adeno Associated Virus ◽

Gene Delivery Vectors ◽

Empty Capsid ◽

Purification Methods ◽

Viral Gene Delivery

: Adeno-associated virus (AAV) is one of the most promising viral gene delivery vectors with long-term gene expression and disease correction featuring high efficiency and excellent safety in human clinical trials. During the production of AAV vectors,there are several quality control (QC)parameters that should be rigorously monitored to comply with clini-cal safety and efficacy. This review gives a short summary of the most frequently used AVV production and purification methods,focusing on the analytical techniques applied to determine the full/empty capsid ratio and the integrity of the encapsidated therapeutic DNA of the products.

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