Development of an Automated High-Throughput Analytical Characterization System for Support of a Central Sample Collection Resource
2003 ◽
Vol 8
(3)
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pp. 55-61
Keyword(s):
On Line
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Ahigh-throughput analytical characterization system was developed for quality control support of a central sample collection resource. This system utilizes liquid chromatography mass spectrometry with in-house developed data automation applications. Continuous operation of analytical instrumentation is accomplished by fully automating sample submission and report processing functions. Comprehensive analytical information characteristic of quality, chemical, and physical properties (e.g. relative purity, detection sensitivity, LogD) are automatically transferred to an on-line database. The application of this database for detailed quality assessment of a small sample library (ca. 24,000 compounds) is demonstrated.
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2002 ◽
Vol 782
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2014 ◽
Vol 965
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2013 ◽
Vol 1317
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2007 ◽
Vol 1152
(1-2)
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pp. 97-115
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