781 Atorvastatin improves endothelial function and depresses inflammatory process in patients with heart failure

2005 ◽  
Vol 4 (1) ◽  
pp. 178-178
2010 ◽  
Vol 142 (1) ◽  
pp. 87-91 ◽  
Author(s):  
Panagiota Gounari ◽  
Dimitris Tousoulis ◽  
Charalambos Antoniades ◽  
Anna Maria Kampoli ◽  
Pavlos Stougiannos ◽  
...  

2017 ◽  
Vol 2017 ◽  
pp. 1-10 ◽  
Author(s):  
M. J. Pearson ◽  
N. A. Smart

Objective. Flow-mediated dilation (FMD) is widely utilised to assess endothelial function and aerobic exercise improves FMD in heart failure patients. The aim of this meta-analysis is to quantify the effect of aerobic training intensity on FMD in patients with heart failure. Background. A large number of studies now exist that examine endothelial function in patients with heart failure. We sought to add to the current literature by quantifying the effect of the aerobic training intensity on endothelial function. Methods. We conducted database searches (PubMed, Embase, ProQuest, and Cochrane Trials Register to June 30, 2016) for exercise based rehabilitation trials in heart failure, using search terms exercise training, endothelial function, and flow-mediated dilation (FMD). Results. The 13 included studies provided a total of 458 participants, 264 in intervention groups, and 194 in nonexercising control groups. Both vigorous and moderate intensity aerobic training significantly improved FMD. Conclusion. Overall both vigorous and moderate aerobic exercise training improved FMD in patients with heart failure.


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