767 Risk factors for bladder cancer recurrence after nephroureterectomy for upper tract urothelial tumors: A multicenter analysis of 742 patients

2012 ◽  
Vol 11 (1) ◽  
pp. e767-e767a
Author(s):  
J. Mauermann ◽  
Y. Fradet ◽  
W. Kassouf ◽  
R. Rendon ◽  
N. Jacobsen ◽  
...  
Keyword(s):  
Risk Factors ◽  
Bladder Cancer ◽  
Cancer Recurrence ◽  
Upper Tract ◽  
Multicenter Analysis ◽  
Urothelial Tumors ◽  
Bladder Cancer Recurrence

Multifocal Carcinoma In Situ of the Upper Tract Is Associated With High Risk of Bladder Cancer Recurrence

2012 ◽  
Vol 61 (5) ◽  
pp. 1069-1070 ◽  
Author(s):  
Evanguelos Xylinas ◽  
Michael Rink ◽  
Vitaly Margulis ◽  
Pierre Karakiewicz ◽  
Giacomo Novara ◽  
...  
Keyword(s):  
Bladder Cancer ◽  
High Risk ◽  
Carcinoma In Situ ◽  
Cancer Recurrence ◽  
Upper Tract ◽  
Bladder Cancer Recurrence

Risk factors for bladder cancer recurrence survival in patients with upper-tract urothelial carcinoma

2018 ◽  
Vol 104 (6) ◽  
pp. 451-458 ◽  
Author(s):  
Yu-Peng Wu ◽  
Yun-Zhi Lin ◽  
Min-Yi Lin ◽  
Ting-Ting Lin ◽  
Shao-Hao Chen ◽  
...  
Keyword(s):  
Bladder Cancer ◽  
Urothelial Carcinoma ◽  
Cancer Recurrence ◽  
Cox Proportional Hazards Model ◽  
Upper Tract Urothelial Carcinoma ◽  
Intravesical Therapy ◽  
Low Grade ◽  
High Grade ◽  
Upper Tract ◽  
Bladder Cancer Recurrence

Purpose: The aim of this work was to investigate the predictive factors for bladder cancer recurrence survival (BCRS) in patients with upper-tract urothelial carcinoma (UTUC). Methods: We selected patients with UTUC who underwent segmental ureterectomy (Su) or nephroureterectomy (Nu) from 2004 to 2013 from the Surveillance, Epidemiology, and End Results (SEER) database. Patients with a history of intravesical therapy for bladder cancer and bladder cancer prior to the diagnosis of UTUC were excluded. We used Kaplan-Meier analysis, log-rank tests, and Cox proportional hazards model to compare overall survival, cancer-specific survival, and BCRS. Results: In a cohort of 1,454 patients, 169 (11.6%) had low-grade tumors and 1,285 (88.4%) had high-grade tumors; 239 (16.4%) underwent Su and 1,215 (83.6%) underwent Nu. We found that T4 grade (hazard ratio [HR] = 6.216; 95% confidence interval [CI], 3.197-12.087) and ureteral tumors (HR = 1.764; 95% CI, 1.173-2.652) were predictors of shorter BCRS, whereas Nu (HR = 0.608; 95% CI, 0.388-0.953) predicted longer BCRS. Five-year BCRS rates were low-grade tumors: 94.1%, high-grade tumors: 85.4% (p = 0.038); plus Su: 82.9%, and Nu: 87.6% (p = 0.016). Conclusions: Use of Su should be more selective for high-grade tumors, as it correlates with shorter BCRS. Tumors located in the ureter are associated with shorter BCRS than those located in the renal pelvis.

scholarly journals PD62-09 MICRORNAS AS BIOMARKERS TO DETERMINE RISK OF BLADDER CANCER RECURRENCE FOLLOWING NEPHROURETERECTOMY FOR UPPER TRACT UROTHELIAL CARCINOMA

2019 ◽  
Vol 201 (Supplement 4) ◽  
Author(s):  
Kareem Alazem* ◽  
Alison Levy ◽  
Travis Sullivan ◽  
Kristian Stensland ◽  
Eric Burks ◽  
...  
Keyword(s):  
Bladder Cancer ◽  
Urothelial Carcinoma ◽  
Cancer Recurrence ◽  
Upper Tract Urothelial Carcinoma ◽  
Upper Tract ◽  
Bladder Cancer Recurrence

255: Risk Factors for Bladder Cancer Recurrence Following Urothelial Carcinoma of the Upper Urinary Tract

2004 ◽  
Vol 171 (4S) ◽  
pp. 67-67
Author(s):  
Brant A. Inman ◽  
Viet-Tan Tran ◽  
François Meyer ◽  
Yves Fradet ◽  
Louis Locombe
Keyword(s):  
Risk Factors ◽  
Bladder Cancer ◽  
Urinary Tract ◽  
Urothelial Carcinoma ◽  
Cancer Recurrence ◽  
Upper Urinary Tract ◽  
Bladder Cancer Recurrence

scholarly journals 5α-reductase inhibitors impact prognosis of urothelial carcinoma

BMC Cancer ◽  
2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Chien-Sheng Wang ◽  
Ching-Chia Li ◽  
Yung-Shun Juan ◽  
Wen-Jeng Wu ◽  
Hsiang-Ying Lee
Keyword(s):  
Bladder Cancer ◽  
Health Insurance ◽  
Urothelial Carcinoma ◽  
Cancer Recurrence ◽  
Upper Tract Urothelial Carcinoma ◽  
Upper Tract ◽  
Reductase Inhibitors ◽  
Health Insurance Database ◽  
Bladder Cancer Recurrence ◽  
Insurance Database

Abstract Background 5α-reductase inhibitors (5-ARIs) inhibit the pathway of converting the testosterone to dihydrotestosterone and are widely used in benign prostatic hyperplasia patients. Since androgen receptor activation may play a role in urothelial tumorigenesis, we conducted this retrospective cohort study to determine whether 5α-reductase inhibitors (5-ARIs) administration is associated with bladder cancer mortality, bladder cancer recurrence and upper tract urothelial carcinoma mortality, using the Taiwan National Health Insurance database. Methods The data of this retrospective cohort study were sourced from the Longitudinal Health Insurance Database of Taiwan, compiled by the Taiwan National Health Insurance database from 1996 to 2010. It consists of 18,530 men with bladder cancer, of whom 474 were 5-ARIs recipients and 4384 men with upper tract urothelial carcinoma, of whom 109 were 5-ARIs recipients. Propensity Score Matching on the age and geographic data was done at the ratio of 1:10. We analyzed the odds ratios (OR) and 95% confidence interval (CI) of the risk of bladder cancer death, bladder cancer recurrence rate and upper tract urothelial carcinoma related death by the 5-ARIs administration. Results Those who received 5-ARIs showed a lower risk of bladder cancer related death compared to nonusers in multivariable adjusted analysis (OR 0.835, 95% CI 0.71–0.98). However, there was no significant difference in the bladder cancer recurrence rate (OR 0.956, 95% CI 0.82–1.11) and upper tract urothelial carcinoma related mortality in multivariable adjusted analysis (OR 0.814, 95% CI 0.6–1.1). Conclusions Patients who receive 5-ARIs have lower bladder cancer related mortality compared to those who don’t. 5-ARIs may prove to be a viable strategy to improve bladder cancer outcomes.

Risk Factors for Subsequent Bladder Cancer Recurrence following Radical Surgery for Upper Urinary Tract Urothelial Cancer

2006 ◽  
Vol 47 (10) ◽  
pp. 1035 ◽  
Author(s):  
Deok Hyun Cho ◽  
Jae Soo Kim ◽  
Hyun Tae Kim ◽  
Eun Sang Yoo ◽  
Tae Gyun Kwon ◽  
...  
Keyword(s):  
Risk Factors ◽  
Bladder Cancer ◽  
Urinary Tract ◽  
Urothelial Cancer ◽  
Radical Surgery ◽  
Cancer Recurrence ◽  
Upper Urinary Tract ◽  
Bladder Cancer Recurrence

238: Combined Effect of Apoptotic Biomarkers on Bladder Cancer Recurrence and Mortality after Radical Cystectomy

2007 ◽  
Vol 177 (4S) ◽  
pp. 79-80
Author(s):  
Jose A. Karam ◽  
Yair Lotan ◽  
Raheela Ashfaq ◽  
Claus G. Roehrborn ◽  
Arthur I. Sagalowsky ◽  
...  
Keyword(s):  
Bladder Cancer ◽  
Radical Cystectomy ◽  
Cancer Recurrence ◽  
Combined Effect ◽  
Bladder Cancer Recurrence
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