Detection of urothelial carcinoma using selected urine-DNA methylation biomarkers in patients with gross hematuria

2018 ◽  
Vol 17 (2) ◽  
pp. e1428
Author(s):  
G. Xiong ◽  
R. Guo ◽  
X. Li ◽  
K. Zhang ◽  
L. Zhou
Keyword(s):  
Dna Methylation ◽  
Urothelial Carcinoma ◽  
Gross Hematuria

scholarly journals Integrative epigenomic analysis of differential DNA methylation in urothelial carcinoma

2015 ◽  
Vol 7 (1) ◽  
Author(s):  
Mattias Aine ◽  
Gottfrid Sjödahl ◽  
Pontus Eriksson ◽  
Srinivas Veerla ◽  
David Lindgren ◽  
...  
Keyword(s):  
Dna Methylation ◽  
Urothelial Carcinoma

scholarly journals Urothelial Carcinoma in a 22-Year-Old Female with Angelman Syndrome

2017 ◽  
Vol 2017 ◽  
pp. 1-3
Author(s):  
Jessica Pugh ◽  
R. Keith Huffaker
Keyword(s):  
Abdominal Pain ◽  
Urothelial Carcinoma ◽  
Angelman Syndrome ◽  
White Female ◽  
Genetic Mutations ◽  
Low Grade ◽  
Gross Hematuria ◽  
Delay In Diagnosis ◽  
History Of

A 22-year-old nulligravid white female with Angelman syndrome was noted to have a 4-month history of premenstrual nausea, vomiting, and abdominal pain. She had an echogenic focus in her bladder noted on ultrasound. She was diagnosed with low grade urothelial carcinoma after cystoscopic evaluation with biopsy and was sent to urology for further treatment. Urothelial carcinoma is rare in individuals younger than age 40. Patients may present with gross hematuria. There is often a delay in diagnosis in younger individuals with different genetic mutations noted upon diagnosis.

scholarly journals HERV-K and LINE-1 DNA Methylation and Reexpression in Urothelial Carcinoma

2013 ◽  
Vol 3 ◽  
Author(s):  
Ulrike Kreimer ◽  
Wolfgang A. Schulz ◽  
Annemarie Koch ◽  
Günter Niegisch ◽  
Wolfgang Goering
Keyword(s):  
Dna Methylation ◽  
Urothelial Carcinoma

scholarly journals Gene Expression and DNA Methylation Status of Glutathione S-Transferase Mu1 and Mu5 in Urothelial Carcinoma

PLoS ONE ◽  
2016 ◽  
Vol 11 (7) ◽  
pp. e0159102 ◽  
Author(s):  
Shou-Chieh Wang ◽  
Chin-Chin Huang ◽  
Cheng-Huang Shen ◽  
Lei-Chen Lin ◽  
Pei-Wen Zhao ◽  
...  
Keyword(s):  
Gene Expression ◽  
Dna Methylation ◽  
Urothelial Carcinoma ◽  
Methylation Status ◽  
Glutathione S Transferase

scholarly journals Metastatic Transitional Cell Carcinoma of the Bladder to the Testis: A Case Report

2012 ◽  
Vol 2012 ◽  
pp. 1-2 ◽  
Author(s):  
Gregory N. Kozak ◽  
Nicholas C. Field
Keyword(s):  
Urothelial Carcinoma ◽  
Lymphovascular Invasion ◽  
Transitional Cell ◽  
Bladder Neck Contracture ◽  
Gross Hematuria ◽  
Metastatic Urothelial Carcinoma ◽  
Poorly Differentiated ◽  
Papillary Urothelial Carcinoma ◽  
Carcinoma Of The Bladder

An 84-year-old gentleman presented with onset of gross hematuria in September 2010. Follow-up investigations revealed T1 superficially invasive, poorly differentiated, papillary urothelial carcinoma. He subsequently had GreenLight laser for BPH and bladder neck contracture on two occasions. He developed a right hydrocele 16 months after initial presentation and during his hydrocelectomy, a rock-hard right epididymis and testicle were discovered. Pathology revealed metastatic urothelial carcinoma replacing nearly the entire testis with lymphovascular invasion.

Genome-wide DNA methylation profiling of upper tract urothelial carcinoma

2018 ◽  
Vol 17 (2) ◽  
pp. e1612
Author(s):  
M.R. Hassler ◽  
S. Kimura ◽  
D. Ilijazi ◽  
W. Pulverer ◽  
D. D’Andrea ◽  
...  
Keyword(s):  
Dna Methylation ◽  
Urothelial Carcinoma ◽  
Upper Tract Urothelial Carcinoma ◽  
Upper Tract ◽  
Genome Wide ◽  
Dna Methylation Profiling ◽  
Methylation Profiling
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