Variation in positive surgical margin status following radical prostatectomy for pT2 prostate cancer

2019 ◽  
Vol 18 (1) ◽  
pp. e294-e295
Author(s):  
W.S. Tan ◽  
M. Krimphove ◽  
A. Cole ◽  
S. Berg ◽  
M. Marchese ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Radical Prostatectomy ◽  
Surgical Margin ◽  
Margin Status ◽  
Positive Surgical Margin

Preoperative Prediction of Surgical Margin Status in Patients With Prostate Cancer Treated by Radical Prostatectomy

2000 ◽  
Vol 18 (15) ◽  
pp. 2862-2868 ◽  
Author(s):  
Liang Cheng ◽  
Jeff Slezak ◽  
Erik J. Bergstralh ◽  
Robert P. Myers ◽  
Horst Zincke ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Radical Prostatectomy ◽  
Confidence Interval ◽  
Odds Ratio ◽  
Surgical Margin ◽  
Margin Status ◽  
Surgical Margins ◽  
Positive Surgical Margin ◽  
Biopsy Specimens ◽  
Preoperative Serum

PURPOSE: We sought to determine the preoperative factors associated with surgical margin status in patients who underwent radical prostatectomy for prostate cancer. PATIENTS AND METHODS: The study group consisted of 339 patients who were treated by radical retropubic prostatectomy and bilateral pelvic lymphadenectomy at the Mayo Clinic. None received preoperative adjuvant therapy. The mean age at the time of surgery was 66 years (range, 45 to 79 years). All specimens were totally embedded and whole-mounted. Positive surgical margin was defined as the presence of cancer cells at the inked margins. Numerous pathologic characteristics in needle biopsies and preoperative clinical findings were analyzed. RESULTS: The overall margin positivity rate was 24%. In univariate analysis, preoperative serum prostate-specific antigen (PSA) level, Gleason score, perineural invasion, percentage of cancer in the biopsy specimens, and number and percentage of biopsy cores involved by cancer were all associated with positive surgical margins. In multivariate analysis, preoperative serum PSA level (odds ratio for a doubling of PSA levels, 1.9; 95% confidence interval, 1.5 to 2.4; P < .001) and percentage of cancer in the biopsy specimens (odds ratio for a 10% increase, 1.3; 95% confidence interval, 1.2 to 1.4; P < .001) were predictive of margin status in radical prostatectomy. With use of preoperative serum PSA level and percentage of cancer in the biopsy as predictors of surgical margins, the overall accuracy as measured by the area under the receiver operating characteristic curve was 0.74. CONCLUSION: Preoperative serum PSA level and percentage of cancer in the biopsy specimens were independently associated with surgical margin status in patients who underwent radical prostatectomy for prostate cancer. The combination of these two factors provides a high level of predictive accuracy for margin status.

scholarly journals Variation in Positive Surgical Margin Status After Radical Prostatectomy for pT2 Prostate Cancer

2019 ◽  
Vol 17 (5) ◽  
pp. e1060-e1068 ◽  
Author(s):  
Wei Shen Tan ◽  
Marieke J. Krimphove ◽  
Alexander P. Cole ◽  
Maya Marchese ◽  
Sebastian Berg ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Radical Prostatectomy ◽  
Surgical Margin ◽  
Margin Status ◽  
Positive Surgical Margin

scholarly journals MP66-05 VARIATION IN POSITIVE SURGICAL MARGIN STATUS FOLLOWING RADICAL PROSTATECTOMY FOR PT2 PROSTATE CANCER

2019 ◽  
Vol 201 (Supplement 4) ◽  
Author(s):  
Wei Shen Tan* ◽  
Marieke Krimphove ◽  
Alexander Cole ◽  
Sebastian Berg, Maya Marchese ◽  
Stuart Lipsitz ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Radical Prostatectomy ◽  
Surgical Margin ◽  
Margin Status ◽  
Positive Surgical Margin

QUALITY IMPROVEMENT IN LAPAROSCOPIC RADICAL PROSTATECTOMY FOR pT2 PROSTATE CANCER: IMPACT OF VIDEO DOCUMENTATION REVIEW ON POSITIVE SURGICAL MARGIN

2005 ◽  
Vol 173 (3) ◽  
pp. 765-768 ◽  
Author(s):  
KARIM TOUIJER ◽  
KENTARO KUROIWA ◽  
JEFFERY W. SARANCHUK ◽  
WALEED A. HASSEN ◽  
EDOUARD J. TRABULSI ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Quality Improvement ◽  
Radical Prostatectomy ◽  
Surgical Margin ◽  
Laparoscopic Radical Prostatectomy ◽  
Positive Surgical Margin ◽  
Video Documentation

scholarly journals Positive Surgical Margin Status after Minimally Invasive Radical Prostatectomy: a Multicenter Study

2015 ◽  
Vol 82 (4) ◽  
pp. 229-237
Author(s):  
Ardit Tafa ◽  
Angelica Grasso ◽  
Alessandro Antonelli ◽  
Pierluigi Bove ◽  
Antonio Celia ◽  
...  
Keyword(s):  
Radical Prostatectomy ◽  
Minimally Invasive ◽  
Multicenter Study ◽  
Surgical Margin ◽  
Margin Status ◽  
Positive Surgical Margin

Positive Surgical Margin Trends In Patients With Pathologic T3 Prostate Cancer Treated With Robot Assisted Radical Prostatectomy

2014 ◽  
pp. 150127063130004 ◽  
Author(s):  
Andrew J. Lightfoot ◽  
Yu-Kai Su ◽  
Shailen Shivam Sehgal ◽  
Ziho Lee ◽  
Giovanni H. Greaves ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Radical Prostatectomy ◽  
Surgical Margin ◽  
Positive Surgical Margin ◽  
Robot Assisted

scholarly journals Surgical margin status and its impact on prostate cancer prognosis after radical prostatectomy: a meta-analysis

2018 ◽  
Vol 36 (11) ◽  
pp. 1803-1815 ◽  
Author(s):  
Lijin Zhang ◽  
Bin Wu ◽  
Zhenlei Zha ◽  
Hu Zhao ◽  
Jun Yuan ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Radical Prostatectomy ◽  
Meta Analysis ◽  
Surgical Margin ◽  
Margin Status ◽  
Cancer Prognosis ◽  
Prostate Cancer Prognosis
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