Differential Diagnosis of LE-specific Skin Lesions

2006 ◽  
pp. 87-101
Author(s):  
Riccardo Rondinone ◽  
Stefania Bano ◽  
Luca Iaccarino ◽  
Andrea Doria
Keyword(s):  
Differential Diagnosis ◽  
Skin Lesions

scholarly journals Skin lesions, differential diagnosis and practical approach to potential survivors of torture

2019 ◽  
Vol 33 (7) ◽  
pp. 1232-1240 ◽  
Author(s):  
K. Clarysse ◽  
M. Grosber ◽  
J. Ring ◽  
J. Gutermuth ◽  
C. Kivlahan
Keyword(s):  
Differential Diagnosis ◽  
Skin Lesions ◽  
Practical Approach ◽  
Survivors Of Torture

scholarly journals Aplasia cutis congenita in a newborn

2021 ◽  
Vol 8 (11) ◽  
pp. 1887
Author(s):  
Sheela Madipelli
Keyword(s):  
Differential Diagnosis ◽  
Newborn Infant ◽  
Skin Lesions ◽  
Congenital Absence ◽  
Aplasia Cutis Congenita ◽  
Surgical Closure ◽  
Live Births ◽  
Common Location ◽  
Scalp Lesion ◽  
Aplasia Cutis

Aplasia cutis congenita (ACC) is a localized congenital absence of skin with a reported incidence of 3 per 10000 live births. Most common location is the scalp. The diagnosis is made clinically. The management of the lesion depends on the size and most of them are managed conservatively but larger lesions need surgical closure. Although aplasia cutis congenita is rare, it is very important for the general pediatrician to recognize this and consider it in the differential diagnosis of skin lesions specially the lesions on the scalp. We present a newborn infant with scalp lesion which was clinically diagnosed as aplasia cutis congenita and was managed conservatively.

scholarly journals Cutaneous Manifestations of Toxoplasmosis: a Case Report

2014 ◽  
Vol 6 (3) ◽  
pp. 113-119 ◽  
Author(s):  
Sonya Marina ◽  
Valja Broshtilova ◽  
Ivo Botev ◽  
Dimitrina Guleva ◽  
Maria Hadzhiivancheva ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Case Report ◽  
Toxoplasma Gondii ◽  
Complete Resolution ◽  
Skin Lesions ◽  
The Body ◽  
Chemiluminescence Immunoassay ◽  
Cutaneous Manifestations ◽  
Blood Eosinophilia ◽  
The World

Abstract Although toxoplasmosis is one of the most widely spread infections in the world, types that involve the skin are extremely rare. However, skin lesions are not specific; moreover, they are quite diverse, which makes the diagnosis of cutaneous toxoplasmosis rather difficult. Thus, differential diagnosis should include a number of other diseases. We present a case of a 43-year-old immunocompetent man with multiple livid erythematous papules and nodules with yellowish discharge that involved the skin of the body and the extremities. By using electro-chemiluminescence immunoassay, immunoglobulin G antibodies to Toxoplasma gondii were detected in the serum, confirming the diagnosis of toxoplasmosis. The treatment with pyrimethamine and trimethoprim-sulfamethoxazole led to complete resolution of skin lesions. In conclusion, although rare in the dermatological practice, cutaneous toxoplasmosis should be considered in all patients presenting with lymphadenopathy, non-specific skin eruptions, especially nodular and colliquative, blood eosinophilia and histological findigs revealing abundant eosinophilic inflitrations.

scholarly journals Peripheral Ulcerative Keratitis with Pyoderma Gangrenosum

2015 ◽  
Vol 2015 ◽  
pp. 1-4
Author(s):  
Adrián Imbernón-Moya ◽  
Elena Vargas-Laguna ◽  
Antonio Aguilar ◽  
Miguel Ángel Gallego ◽  
Claudia Vergara ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Pyoderma Gangrenosum ◽  
Early Recognition ◽  
Skin Lesions ◽  
Unusual Event ◽  
Peripheral Ulcerative Keratitis ◽  
Appropriate Treatment ◽  
Autoimmune Conditions ◽  
Ulcerative Keratitis ◽  
Peripheral Cornea

Pyoderma gangrenosum is an unusual necrotizing noninfective and ulcerative skin disease whose cause is unknown. Ophthalmic involvement in pyoderma gangrenosum is an unusual event. Only a few cases have been reported, from which we can highlight scleral, corneal, and orbital cases. Peripheral ulcerative keratitis is a process which destroys the peripheral cornea. Its cause is still unknown although it is often associated with autoimmune conditions. Pyoderma gangrenosum should be included in the differential diagnosis of peripheral ulcerative keratitis. Early recognition of these manifestations can vary the prognosis by applying the appropriate treatment. We introduce a 70-year-old woman who suffered pyoderma gangrenosum associated with peripheral ulcerative keratitis in her left eye. The patient’s skin lesions and peripheral keratitis responded successfully to systemic steroids and cyclosporine A.

scholarly journals Remission of Thymoma on Steroid Therapy in a Patient With Atypical Thymoma-Associated Multiorgan Autoimmunity: A Case Report and Literature Review

2021 ◽  
Vol 12 ◽  
Author(s):  
Ewa Wrona ◽  
Sylwia Dębska-Szmich ◽  
Marta Pastuszka ◽  
Marcin Braun ◽  
Rafał Czyżykowski ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Case Report ◽  
Literature Review ◽  
Symptom Management ◽  
Partial Remission ◽  
Skin Lesions ◽  
Humoral Autoimmunity ◽  
Rare Phenomena ◽  
Tumor Remission

In up to 34% of cases, thymoma, itself a rare neoplasm, is accompanied by autoimmune disorders, two of which are thymoma-associated multiorgan autoimmunity (TAMA) and paraneoplastic autoimmune multiorgan syndrome (PAMS). Unfortunately, differential diagnosis between these two entities can be challenging since no strict PAMS definition exists and PAMS can overlap with a subgroup of TAMA patients with skin lesions as leading presentation. We present a case of a 68-year-old woman with a diagnosis of thymoma accompanied by myasthenia gravis, hypothyroidism and GvHD-like mucocutaneous lesions that initially could account to both TAMA and PAMS diagnosis. However, following the exclusion of humoral autoimmunity against components of epithelial cells junction, TAMA was finally established. Interestingly, the introduction of corticosteroid therapy for TAMA symptom management resulted in unexpected partial remission of thymoma with no impact on mucocutaneous lesions. Our case study is an example of two extremely rare phenomena accompanying thymomas: unprecedented TAMA presentation with GvHD-like mucositis, which as we postulate should be placed in the spectrum of TAMA, and tumor remission on steroids.

scholarly journals Integration of Dermatology-Focused Physical Diagnosis Rounds and Case-Based Learning within the Internal Medicine Medical Student Clerkship

2016 ◽  
Vol 3 ◽  
pp. JMECD.S40417 ◽  
Author(s):  
Brian L. Scott ◽  
Blake Barker ◽  
Reeni Abraham ◽  
Heather W. Wickless
Keyword(s):  
Internal Medicine ◽  
Differential Diagnosis ◽  
Medical Students ◽  
Response Rate ◽  
Skin Lesions ◽  
Learning Session ◽  
Physical Diagnosis ◽  
Case Based Learning ◽  
Shelf Exam ◽  
Case Based

Background Over half of dermatologic conditions are seen by nondermatologists, yet medical students receive little dermatology education. Medical students in the clinical years of training at our institution felt insecure in their physical diagnosis skills for dermatologic conditions. Objective The objective of this study was to implement dermatology-focused curricula within the Internal Medicine (IM) Core Clerkship to increase student confidence in diagnosing skin diseases. Methods Two dermatology-focused sessions were integrated into the IM Clerkship. A faculty dermatologist leads students on a dermatology-focused physical diagnosis “Skin Rounds”, where patients are seen at the bedside and students practice describing skin lesions and forming a differential diagnosis. Students also participate in a case-based active learning session. A dermatologist selects images of common skin conditions that students describe utilizing appropriate terminology and offer a differential diagnosis. The impact of these sessions was assessed through survey-based student feedback and by comparing the results from the IM Shelf Exam before and after intervention. Results A total of 74 students completed the skin rounds survey (32% response rate). About 99% ( n = 73) of students felt that skin rounds were effective and useful, and 92% ( n = 68) of students reported that they felt more confident in describing skin lesions afterward. A total of 43 students completed the case-based learning session survey (37% response rate), and 98% ( n = 42) of students strongly agreed or agreed that the session was effective and useful. Performance on the dermatologic questions of the IM Shelf Exam was analyzed. While not statistically significant at P < 0.05, students improved from an average of 77% correct responses before intervention to 79% afterward ( P = 0.60). Conclusions Our case-based and bedside teaching interventions were met with high satisfaction from medical students and increased their confidence in describing skin lesions. This intervention can serve as a model to improve dermatology education and can be adapted to utilize the IM clerkship to address curriculum inadequacies at other institutions.

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