Reliability and Validity of the Taiwan Chinese Version of the EORTC QLQ-PR25 in Assessing Quality of Life of Prostate Cancer Patients

PURPOSE The European Organization for Research and Treatment of Cancer Core Quality of Life Questionnaire (EORTC QLQ-C30) is a well-validated instrument that assesses health-related quality of life (HRQOL) in cancer patients. It is used in cancer clinical trials in Europe, Canada, and the United States, and has demonstrated high reliability and validity in different groups of cancer patients. Despite thorough testing of reliability and validity, we have not identified any reports on its test/retest reliability; thus, a test/retest study was performed at the Norwegian Radium Hospital (NRH). MATERIALS AND METHODS Cancer patients from the outpatient clinic who were off treatment for > or = 3 months were eligible for the study. The EORTC QLQ-C30 was given to the patients when they presented for their visit. The second questionnaire was received by the patients 4 days later. Of 291 eligible patients, 270 (93%) agreed to participate and 190 (73%) completed both questionnaires. RESULTS The test/retest reliability measured by Pearson's correlation coefficient was high for all functional scales, with a range from .82 for cognitive and role function to .91 for physical function. The r value for global HRQOL was .85. For the symptom scales--nausea/vomiting, fatigue, and pain--the coefficients were .63, .83, and .86, respectively. The single-item coefficients ranged from .72 for diarrhea to .84 for financial impact. The Spearman rank correlation was in the same range for all dimensions. CONCLUSION The EORTC QLQ-C30 seems to yield high test/retest reliability in patients with various cancer diagnoses whose condition is not expected to change during the time of measurement.

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Psychometric evaluation of the Taiwan Chinese version of the EORTC QLQ-PR25 for HRQOL assessment in prostate cancer patients

Health and Quality of Life Outcomes ◽

10.1186/1477-7525-10-96 ◽

2012 ◽

Vol 10 (1) ◽

pp. 96 ◽

Cited By ~ 8

Author(s):

Yu-Jun Chang ◽

Wen-Miin Liang ◽

Hsi-Chin Wu ◽

Hsueh-Chun Lin ◽

Jong-Yi Wang ◽

...

Keyword(s):

Prostate Cancer ◽

Cancer Patients ◽

Psychometric Evaluation ◽

Chinese Version ◽

Taiwan Chinese ◽

Hrqol Assessment ◽

Eortc Qlq

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Reliability and validity of the EORTC QLQ-C30 in palliative care cancer patients

Open Medicine ◽

10.2478/s11536-009-0032-7 ◽

2009 ◽

Vol 4 (3) ◽

pp. 348-357 ◽

Cited By ~ 10

Author(s):

Hubert Jocham ◽

Theo Dassen ◽

Guy Widdershoven ◽

Ruud Halfens

Keyword(s):

Quality Of Life ◽

Palliative Care ◽

Cancer Patients ◽

Symptom Control ◽

Reliability And Validity ◽

European Organization ◽

Wide Range ◽

Eortc Qlq C30 ◽

Eortc Qlq

AbstractPalliative care aims at improving the patient’s quality of life. The assessment of this quality of life (QoL) is crucial for the evaluation of palliative care outcome. Many patients require hospital admissions for symptom control during their cancer journey and most of them die in hospitals, although they would like to stay at home until the end of their lives. In 1986, the European Organization for Research and Treatment (EORTC) initiated a research programme to develop an integrated, modular approach for evaluating the quality of life of patients participating in international clinical trials. This questionnaire measures cancer patients’ physical, psychological and social functions and was used in a wide range of clinical cancer trials with large numbers of research groups and also in various other non-trial studies. The aim of this study was to evaluate the psychometric properties, especially the reliability, validity and applicability of the EORTC QLQ-C30 in a German sample of terminally ill cancer patients receiving palliative care in different settings. The questionnaire was well accepted in the present patient population. Scale reliability was good (pre-treatment 0.80) especially for the functional scale. The results support the reliability and validity of the QLQ-C30 (version 3.0) as a measure of the health-related quality of life in German cancer patients receiving palliative care treatment.

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Cancer Related Fatigue and Quality of Life in Patients with Advanced Prostate Cancer Undergoing Chemotherapy

BioMed Research International ◽

10.1155/2016/3989286 ◽

2016 ◽

Vol 2016 ◽

pp. 1-11 ◽

Cited By ~ 22

Author(s):

Andreas Charalambous ◽

Christiana Kouta

Keyword(s):

Quality Of Life ◽

Prostate Cancer ◽

Cancer Patients ◽

Advanced Prostate Cancer ◽

Survival Times ◽

Structured Interviews ◽

Cross Sectional ◽

Cancer Related Fatigue ◽

Eortc Qlq

Cancer related fatigue (CRF) is a common and debilitating symptom that can influence quality of life (QoL) in cancer patients. The increase in survival times stresses for a better understanding of how CRF affects patients’ QoL. This was a cross-sectional descriptive study with 148 randomly recruited prostate cancer patients aiming to explore CRF and its impact on QoL. Assessments included the Cancer Fatigue Scale, EORTC QLQ-C30, and EORTC QLQ-PR25. Additionally, 15 in-depth structured interviews were performed. Quantitative data were analyzed with simple and multiple regression analysis and independent samplest-test. Qualitative data were analyzed with the use of thematic content analysis. The 66.9% of the patients experienced CRF with higher levels being recorded for the affective subscale. Statistically significant differences were found between the patients reporting CRF and lower levels of QoL (mean = 49.1) and those that did not report fatigue and had higher levels of QoL (mean = 72.1). The interviews emphasized CRF’s profound impact on the patients’ lives that was reflected on the following themes: “dependency on others,” “loss of power over decision making,” and “daily living disruption.” Cancer related fatigue is a significant problem for patients with advanced prostate cancer and one that affects their QoL in various ways.

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