scholarly journals Validation of the Taiwan Chinese version of the EORTC QLQ-CR29 to assess quality of life in colorectal cancer patients

BMC Cancer ◽  
2018 ◽  
Vol 18 (1) ◽  
Author(s):  
Ming-Hung Shen ◽  
Ling-Ping Chen ◽  
Thien-Fiew Ho ◽  
Ying-Yih Shih ◽  
Ching-Shui Huang ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Colorectal Cancer ◽  
Cancer Patients ◽  
Chinese Version ◽  
Taiwan Chinese ◽  
Assess Quality ◽  
Eortc Qlq ◽  
Colorectal Cancer Patients

scholarly journals QUALITY OF LIFE AMONG COLORECTAL CANCER PATIENTS AT THAI NGUYEN ONCOLOGY CENTER

2021 ◽  
Vol 62 (4) ◽  
Author(s):  
Nguyen To Quynh Chau ◽  
Nguyen Manh Tuan ◽  
Nguyen Thanh Nhai ◽  
Nguyen Thi Ngan ◽  
Tran Bao Ngoc
Keyword(s):  
Quality Of Life ◽  
Colorectal Cancer ◽  
Cancer Patients ◽  
Cross Sectional Study ◽  
Functional Score ◽  
Cross Sectional ◽  
European Organization ◽  
Eortc Qlq ◽  
Colorectal Cancer Patients

Aim: To describe quality life’s colorectal cancer patients who are being treated at Thai Nguyenoncology center from June 2020 to August 2020.Objects and method: The descriptive cross- sectional study was conducted over 68 patientsdiagnosed with colorectal cancer by face to face interview using the European Organization forResearch and Treatment of Cancer (EORTC) QLQ-C30 and the EORTC QLQ-CR29.Results: Mean of overall health score was 51,96±18,78; mean of functional score was 21,49±12,42(1,71–47,06). In functional sector, social function was scored lowest. In symptomatic scale, appetiteloss was scored highest (47,06).Conclusion: Quality of life of colorectal cancer patients was medium level. Highest scores wereobserved for appetite loss and fatigue. To improve quality life’s patients, medical staffs need to keepenhancing symptoms and function for patients during treatment.

scholarly journals Validation of the Arabic version of the EORTC Colorectal (CR29) module in Moroccan  colorectal cancer patients

2021 ◽  
Author(s):  
Yacir El Alami ◽  
Houda Bachri ◽  
Hajar Essangri ◽  
Said Benamer ◽  
Amine Benkabbou ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Colorectal Cancer ◽  
Cancer Patients ◽  
Life Questionnaire ◽  
Arabic Version ◽  
Frequency Scale ◽  
Moroccan Arabic ◽  
Eortc Qlq ◽  
Colorectal Cancer Patients

Abstract Purpose: Quality of life outcomes are a focal endpoint of cancer treatment strategies which can be evaluated through patient-related outcome measures (PROMs). We aim to validate the Moroccan Arabic version of the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire for Colorectal cancer patients (EORTC QLQ CR-29).Methods: Following translation to Moroccan Arabic, the QLQ CR-29 was administered to patients treated for colorectal cancer (CRC) in the national institute of oncology. Psychometric properties were tested by measuring Cronbach’s alpha coefficient for reliability and Intraclass correlation coefficient(ICC) to examine test-retest reproducibility. The multitrait-scaling analysis was performed to demonstrate the validity of the instrument and the ability to discriminate between different patient groups was tested using known-groups comparison.Results: In total, 221 patients were included in our study and 34 patients completed the questionnaire twice. The urinary Frequency scale and Stool Frequency scale had good internal consistency with alpha Cronbach coefficients of 0,79 and 0,83 respectively, whereas the coefficient was moderately lower for the Blood and Mucus in Stool scale (0,61) and the Body Image scale (0,67). The ICCs ranged from 0,88 to 1 indicating good to excellent reproducibility. In multitrait scaling analyses, the criterion for item convergent and divergent validity was satisfactory. The known-group comparison showed statistically significant differences between patients according to age, gender, stoma status, tumor location, and radiotherapy. Conclusion: The Moroccan Arabic version of the EORTC QLQ-CR29 is a valid and reliable tool and can be used for research and clinical purposes in Moroccan CRC patients.

scholarly journals Construct Validity and Reliability of the European Organization for Research and Treatment of Cancer Quality of Life Tool Among Colorectal Cancer Patients in Ethiopia

2021 ◽  
Author(s):  
Lidya Genene Abebe ◽  
Abigiya Wondimagegnehu ◽  
Aynalem Abraha Woldemariam ◽  
Bizu Gelaye ◽  
Eva Johanna Kantelhardt ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Colorectal Cancer ◽  
Construct Validity ◽  
Cancer Patients ◽  
Life Questionnaire ◽  
Validity And Reliability ◽  
European Organization ◽  
Eortc Qlq ◽  
Colorectal Cancer Patients

Abstract Background: Colorectal cancer and its treatments can have a detrimental effect on patients’ quality of life. The European Organization for Research and Treatment of Cancer Quality of Life questionnaire (EORTC-QLQ) was developed to assess quality of life among colorectal cancer patients and is used worldwide. However, the tool has not been translated into a local language or validated in the Ethiopian context. Therefore, this study aimed to examine the psychometric properties of the EORTC-QLQ in Ethiopia among colorectal cancer patients.Methods: A cross-sectional study was conducted in a major referral hospital in Addis Ababa, Ethiopia from March to May, 2020. A total of 158 colorectal cancer patients were consecutively included. The construct validity was assessed using Multitrait Scale Analysis, convergent validity, and relationship with functional outcomes. The internal consistency was examined using Cronbach’s alpha.Result: Among the participants, 52.2% were men, with a median age of 46 years (IQR = 17.7 years). The time needed to complete the EORTC-QLQ was less than 20 minutes. The item-total correlation alpha values ranged from 0.47–0.91. All item correlations within their scales were greater than 0.4 except for the Blood and Mucus in Stool scale. The value of correlation coefficients between all items and their own domain were higher than other domains, except for the Blood and Mucus in Stool scale. The correlation between the core questionnaire and the colorectal tool ranged from -0.453–0.581. The tool showed a significant difference between stoma and non-stoma patients, and between patients who had good physical function and those who did not.Conclusion: Except for the Blood and Mucus in Stool scale, the construct validity and reliability of all scales were supported. Therefore, the Amharic version of the tool can be used to assess health related quality of life in Ethiopian colorectal cancer patients. However, due to the low correlation between items in the Blood and Mucus in Stool scale, we recommend that these items are treated as a single item.

scholarly journals Patient-Reported Outcomes of Colorectal Cancer Patients in University Malaya Medical Centre

2018 ◽  
Vol 4 (Supplement 2) ◽  
pp. 102s-102s
Author(s):  
B.A. Magaji ◽  
F.M. Moy ◽  
C.W. Law ◽  
A.C. Roslani
Keyword(s):  
Quality Of Life ◽  
Colorectal Cancer ◽  
Cancer Patients ◽  
Patient Reported ◽  
Related Quality ◽  
Health Related ◽  
Eortc Qlq ◽  
Colorectal Cancer Patients ◽  
Malaysian Chinese

Background: In Malaysia, colorectal cancer is ranked the second most frequent cancer among men and women. Despite that, research on patient-reported outcomes in colorectal cancer is scarce. Aim: This study aimed to determine the pattern and factors affecting health-related quality of life (HRQOL) among colorectal cancer patients treated at the University Malaya Medical Centre (UMMC), Malaysia. Methods: This study is a cross sectional assessment of health-related quality of life of colorectal cancer patients attending UMMC using locally validated Bahasa Malaysia (BM) and Malaysian Chinese versions of the EORTC QLQ-C30 core and colorectal cancer specific EORTC-QLQ-CR29 tools. Data were drawn from patients' records, national registration department and interviews (physical and telephone). Statistical analyses included descriptive, psychometric evaluations and stepwise multiple linear regression models. Results: The reliability and validity of the BM and Malaysian Chinese tools were examined among 189 patients. The questionnaires were acceptable to the patients, with adequate Cronbach's alpha in all but the cognitive function scale, test-retest coefficient were adequate, and all items fulfilled the criteria for convergent and discriminant validity except question number 5 in QLQ-C30 in both the tools. Three hundred and twenty patients not involved in the validation study were surveyed and these patients rated their global health status/quality of life (GHS/QOL) and functional well-being higher than the EORTC reference values and reported fewer symptoms. Ethnicity was associated with the GHS/QOL at univariate level only. Role, social/family functioning scales were the two independent predictors of GHS/QOL and both are modifiable. Conclusion: Proactive engagement of patients to share their experiences with colorectal cancer and its treatment is recommended. Emphasis should be role, social and family functions, which were found to be proxies for the overall GHS/QOL.

Validation of the Arabic version of the EORTC Colorectal (CR29) module in Moroccan  colorectal cancer patients

2020 ◽  
Author(s):  
Yacir El Alami ◽  
Houda Bachri ◽  
Hajar Essangri ◽  
Said Benamer ◽  
Amine Benkabbou ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Colorectal Cancer ◽  
Cancer Patients ◽  
Life Questionnaire ◽  
Arabic Version ◽  
Frequency Scale ◽  
Moroccan Arabic ◽  
Eortc Qlq ◽  
Colorectal Cancer Patients

Abstract Purpose Quality of life outcomes are a focal endpoint of cancer treatment strategies which can be evaluated through patient-related outcome measures (PROMs). We aim to validate the Moroccan Arabic version of the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire for Colorectal cancer patients (EORTC QLQ CR-29). Methods Following translation to Moroccan Arabic, the QLQ CR-29 was administered to patients treated for colorectal cancer (CRC) in the national institute of oncology. Psychometric properties were tested by measuring Cronbach’s alpha coefficient for reliability and Intraclass correlation coefficient(ICC) to examine test-retest reproducibility. The multitrait-scaling analysis was performed to demonstrate the validity of the instrument and the ability to discriminate between different patient groups was tested using known-groups comparison. Results In total, 221 patients were included in our study and 34 patients completed the questionnaire twice. The urinary Frequency scale and Stool Frequency scale had good internal consistency with alpha Cronbach coefficients of 0,79 and 0,83 respectively, whereas the coefficient was moderately lower for the Blood and Mucus in Stool scale (0,61) and the Body Image scale (0,67). The ICCs ranged from 0,88 to 1 indicating good to excellent reproducibility. In multitrait scaling analyses, the criterion for item convergent and divergent validity was satisfactory. The known-group comparison showed statistically significant differences between patients according to age, gender, stoma status, tumor location, and radiotherapy. Conclusion The Moroccan Arabic version of the EORTC QLQ-CR29 is a valid and reliable tool and can be used for research and clinical purposes in Moroccan CRC patients.

Safety and Quality of Life in the Treatment of Non-metastasic Colorectal Cancer Patients: 5-fluorouracil Versus Capecitabine

2019 ◽  
Author(s):  
Julia Sánchez-Gundín ◽  
Cristina Martín-Sabroso ◽  
Ana M. Fernández-Carballido ◽  
D. Barreda-Hernández ◽  
Ana I. Torres-Suárez
Keyword(s):  
Quality Of Life ◽  
Colorectal Cancer ◽  
Cancer Patients ◽  
Colorectal Cancer Patients

scholarly journals Psychometric validation of the Moroccan version of the EORTC QLQ-C30 in colorectal Cancer patients: cross-sectional study and systematic literature review

BMC Cancer ◽  
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Yacir El Alami ◽  
Hajar Essangri ◽  
Mohammed Anass Majbar ◽  
Saber Boutayeb ◽  
Said Benamr ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Colorectal Cancer ◽  
Discriminant Validity ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Related Quality ◽  
Eortc Qlq C30 ◽  
Eortc Qlq ◽  
Colorectal Cancer Patients

Abstract Background Health-related quality of life is mainly impacted by colorectal cancer which justified the major importance addressed to the development and validation of assessment questionnaires. We aimed to assess the validity and reliability of the Moroccan Arabic Dialectal version of the European Organization for Research and Treatment of Cancer (EORTC) Quality of Life Core Questionnaire (QLQ-C30) in patients with colorectal cancer. Methods We conducted a cross-sectional study using the Moroccan version of the EORTC QLQ-C30 on colorectal cancer patients from the National Oncology Institute of Rabat, in the period from February 2015 to June 2017. The QLQ-C30 was administered to 120 patients. Statistical analysis included reliability, convergent, and discriminant validity as well as known-groups comparisons. Results In total, 120 patients with colorectal cancer were included in the study with 38 (32%) patients diagnosed with colon cancers. Eighty-two patients (68%) had rectal cancer, among which 29 (24%) patients with a stoma. The mean age of diagnosis was 54 years (+/− 13.3). The reliability and validity of the Arabic dialectal Moroccan version of the EORTC QLQ-C30 were satisfactory. [Cronbach’s alpha (α =0.74)]. All items accomplished the criteria for convergent and discriminant validity except for question number 5, which did not complete the minimum required correlation with its own scale (physical functioning). Patients with rectal cancer presented with bad Global health status and quality of life (GHS/QOL), emotional functioning as well as higher fatigue symptoms compared to patients with colon cancer. The difference between patients with and without stoma was significant for diarrhea and financial difficulty. Conclusions The Moroccan Arabic Dialectal version of the QLQ-C30 is a valid and reliable measure of health-related quality of life (HRQOL) in patients with colorectal cancer.

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