scholarly journals Antioxidant, lipid peroxidation inhibition and free radical scavenging efficacy of a diterpenoid compound sugiol isolated from Metasequoia glyptostroboides

2014 ◽  
Vol 7 (1) ◽  
pp. 9-15 ◽  
Author(s):  
Vivek K. Bajpai ◽  
Ajay Sharma ◽  
Sun Chul Kang ◽  
Kwang-Hyun Baek
Keyword(s):  
Lipid Peroxidation ◽  
Free Radical ◽  
Radical Scavenging ◽  
Free Radical Scavenging ◽  
Metasequoia Glyptostroboides ◽  
Lipid Peroxidation Inhibition

scholarly journals A Novel Isopimarane Diterpenoid with Acetylcholinesterase Inhibitory Activity from Nepeta sorgerae, an Endemic Species to the Nemrut Mountain

2012 ◽  
Vol 7 (6) ◽  
pp. 1934578X1200700
Author(s):  
Anıl Yılmaz ◽  
Pınar Çağlar ◽  
Tuncay Dirmenci ◽  
Nezhun Gören ◽  
Gülaçtı Topçu
Keyword(s):  
Lipid Peroxidation ◽  
Antioxidant Activity ◽  
Free Radical ◽  
Endemic Species ◽  
Structure Elucidation ◽  
Radical Scavenging ◽  
Free Radical Scavenging ◽  
Lipid Peroxidation Inhibition ◽  
Ellman’S Method ◽  
Β Carotene

From the dichloromethane extract of Nepeta sorgerae, the isolation and structure elucidation are now reported of a new isopimarane diterpenoid, named sorgerolone, and two known triterpenoids, oleanolic acid and ursolic acid. Antioxidant activity of the extracts and the isolated terpenoids was determined by the DPPH free radical scavenging and lipid peroxidation inhibition (β-carotene bleaching) methods. Anticholinesterase activity of the extracts and isolates was investigated by Ellman's method against AChE and BChE enzymes. Although the antioxidant activity results were low, the AChE enzyme inhibition of the extracts and terpenoids was very promising.

Free Radical Scavenging and Lipid Peroxidation Inhibition Potential of Various Fractions of Murraya paniculata

Pharmacologia ◽  
2012 ◽  
Vol 3 (5) ◽  
pp. 138-143 ◽  
Author(s):  
R. Paramaguru ◽  
P. Silambu Janaki ◽  
M. Bavani Eswaran ◽  
Ch.V. Rao ◽  
A.K.S. Rawat ◽  
...  
Keyword(s):  
Lipid Peroxidation ◽  
Free Radical ◽  
Radical Scavenging ◽  
Free Radical Scavenging ◽  
Murraya Paniculata ◽  
Lipid Peroxidation Inhibition

Evaluation of lipid peroxidation inhibition and free radical scavenging abilities of 5,6,7-trimethoxy dihydroflavonols

2009 ◽  
Vol 20 (10) ◽  
pp. 1187-1190 ◽  
Author(s):  
Ke Xin Huang ◽  
Yu Bing Feng ◽  
Wei Yao ◽  
Lei Xiang Yang ◽  
Feng Wang ◽  
...  
Keyword(s):  
Lipid Peroxidation ◽  
Free Radical ◽  
Radical Scavenging ◽  
Free Radical Scavenging ◽  
Lipid Peroxidation Inhibition

Investigation of Free Radical Scavenging Enzyme Activities and Lipid Peroxidation in Human Placental Tissues With Miscarriage

2006 ◽  
Vol 13 (5) ◽  
pp. 384-388 ◽  
Author(s):  
Aydan Biri ◽  
Mustafa Kavutcu ◽  
Nuray Bozkurt ◽  
Erdinç Devrim ◽  
Nilhan Nurlu ◽  
...  
Keyword(s):  
Lipid Peroxidation ◽  
Free Radical ◽  
Enzyme Activities ◽  
Radical Scavenging ◽  
Free Radical Scavenging

Antioxidant and Hepatoprotective Effects of Orthosiphon stamineus Benth.

2007 ◽  
Vol 35 (01) ◽  
pp. 115-126 ◽  
Author(s):  
Mun Fei Yam ◽  
Rusliza Basir ◽  
Mohd. Zaini Asmawi ◽  
Zhari Ismail
Keyword(s):  
Lipid Peroxidation ◽  
Free Radical ◽  
Liver Toxicity ◽  
Radical Scavenging ◽  
Water Extract ◽  
Liver Function Tests ◽  
Hepatoprotective Activity ◽  
Free Radical Scavenging ◽  
Trolox Equivalent Antioxidant Capacity ◽  
Orthosiphon Stamineus

Orthosiphon stamineus (OS), Benth. (Lamiaceae) is widely used in Malaysia for treatments of various kidney and liver ailments. In the experiment, DPPH• radicals scavenging, Fe 3+-induced lipid peroxidation inhibiting activities and trolox equivalent antioxidant capacity (TEAC) of methanol/water extract of Orthosiphon stamineus (SEOS) were determined. The results indicated that SEOS exhibited antioxidant, lipid peroxidation inhibition and free radical scavenging activities. The hepatoprotective activity of the SEOS was studied using CCl 4-induced liver toxicity in rats. The activity was assessed by monitoring liver function tests through the measurement of alanine transaminase (ALT) and aspartate transaminase (AST). Furthermore, hepatic tissues were also subjected to histopathological studies. Pretreatment of SEOS (125, 250, 500 and 1000 mg/kg p.o.) dose-dependently reduced the necrotic changes in rat liver and inhibited the increase of serum ALT and AST activities. The results of the present study indicated that the hepatoprotective effect of Orthosiphon stamineus might be ascribable to its antioxidant and free radical scavenging property.

scholarly journals Constituents of the Stem of Nauclea orientalis

2015 ◽  
Vol 10 (11) ◽  
pp. 1934578X1501001 ◽  
Author(s):  
Phan Thi Anh Dao ◽  
Tran Le Quan ◽  
Nguyen Thi Thanh Mai
Keyword(s):  
Lipid Peroxidation ◽  
Antioxidant Activity ◽  
Free Radical ◽  
Spectroscopic Data ◽  
Radical Scavenging ◽  
Free Radical Scavenging ◽  
Propanoic Acid ◽  
Coumaric Acid ◽  
Aloe Emodin ◽  
Inhibitory Activities

A new α-pinene derivative (1) was isolated from the stem of Nauclea orientalis (L.) L. (Rubiaceae), together with twelve known compounds, including four terpenoids, loganetin (2), loganin (3), sweroside (4), grandifloroside (5), four simple phenols, methyl protocatechuate (6), trans- p-coumaric acid (7), 3-(2,4-dihydroxylphenyl)propanoic acid (8), methyl 3-(2,4-dihydroxylphenyl)propanoate (9), two coumarin glucosides, skimmin (10), adicardin (11), an anthraquinone, aloe emodin (12), and a lignan, (+)-pinoresinol (13). Their structures were elucidated on the basis of spectroscopic data. All compounds were tested for DPPH free radical scavenging and lipid peroxidation inhibitory activities. Among them, compounds 5 and 6 displayed strong antioxidant activity with IC50 values of 6.6 and 67.9 μM, 12.4 and 813.0 μM, respectively.

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